BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 31831844)

  • 1. NPM1c impedes CTCF functions through cytoplasmic mislocalization in acute myeloid leukemia.
    Wang AJ; Han Y; Jia N; Chen P; Minden MD
    Leukemia; 2020 May; 34(5):1278-1290. PubMed ID: 31831844
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells.
    Ghasemi R; Struthers H; Wilson ER; Spencer DH
    Leukemia; 2021 Feb; 35(2):404-416. PubMed ID: 32398790
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant NPM1 Maintains the Leukemic State through HOX Expression.
    Brunetti L; Gundry MC; Sorcini D; Guzman AG; Huang YH; Ramabadran R; Gionfriddo I; Mezzasoma F; Milano F; Nabet B; Buckley DL; Kornblau SM; Lin CY; Sportoletti P; Martelli MP; Falini B; Goodell MA
    Cancer Cell; 2018 Sep; 34(3):499-512.e9. PubMed ID: 30205049
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.
    Nabbouh AI; Hleihel RS; Saliba JL; Karam MM; Hamie MH; Wu HJM; Berthier CP; Tawil NM; Bonnet PA; Deleuze-Masquefa C; El Hajj HA
    Cancer; 2017 May; 123(9):1662-1673. PubMed ID: 28055106
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.
    Vascotto C; Lirussi L; Poletto M; Tiribelli M; Damiani D; Fabbro D; Damante G; Demple B; Colombo E; Tell G
    Oncogene; 2014 May; 33(22):2876-87. PubMed ID: 23831574
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia.
    Zhu G; Luo H; Feng Y; Guryanova OA; Xu J; Chen S; Lai Q; Sharma A; Xu B; Zhao Z; Feng R; Ni H; Claxton D; Guo Y; Mesa RA; Qiu Y; Yang FC; Li W; Nimer SD; Huang S; Xu M
    Nat Commun; 2021 Mar; 12(1):1956. PubMed ID: 33782403
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EAPB0503, an Imidazoquinoxaline Derivative Modulates SENP3/ARF Mediated SUMOylation, and Induces NPM1c Degradation in NPM1 Mutant AML.
    Skayneh H; Jishi B; Hleihel R; Hamie M; El Hajj R; Deleuze-Masquefa C; Bonnet PA; El Sabban M; El Hajj H
    Int J Mol Sci; 2022 Mar; 23(7):. PubMed ID: 35408798
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto
    Oka M; Mura S; Otani M; Miyamoto Y; Nogami J; Maehara K; Harada A; Tachibana T; Yoneda Y; Ohkawa Y
    Elife; 2019 Nov; 8():. PubMed ID: 31755865
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Curious Novel Combination of
    Venanzi A; Rossi R; Martino G; Annibali O; Avvisati G; Mameli MG; Sportoletti P; Tiacci E; Falini B; Martelli MP
    Genes (Basel); 2021 Sep; 12(9):. PubMed ID: 34573408
    [No Abstract]   [Full Text] [Related]  

  • 10. HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia.
    Luo H; Zhu G; Eshelman MA; Fung TK; Lai Q; Wang F; Zeisig BB; Lesperance J; Ma X; Chen S; Cesari N; Cogle C; Chen B; Xu B; Yang FC; So CWE; Qiu Y; Xu M; Huang S
    Mol Cell; 2022 Feb; 82(4):833-851.e11. PubMed ID: 35180428
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1.
    Balusu R; Fiskus W; Rao R; Chong DG; Nalluri S; Mudunuru U; Ma H; Chen L; Venkannagari S; Ha K; Abhyankar S; Williams C; McGuirk J; Khoury HJ; Ustun C; Bhalla KN
    Blood; 2011 Sep; 118(11):3096-106. PubMed ID: 21719597
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding.
    Mujahed H; Miliara S; Neddermeyer A; Bengtzén S; Nilsson C; Deneberg S; Cordeddu L; Ekwall K; Lennartsson A; Lehmann S
    Blood; 2020 Jul; 136(3):339-352. PubMed ID: 32232485
    [TBL] [Abstract][Full Text] [Related]  

  • 13. When the good go bad: Mutant NPM1 in acute myeloid leukemia.
    Kunchala P; Kuravi S; Jensen R; McGuirk J; Balusu R
    Blood Rev; 2018 May; 32(3):167-183. PubMed ID: 29157973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Could Targeting NPM1c+ Misfolding Be a Promising Strategy for Combating Acute Myeloid Leukemia?
    Florio D; Marasco D
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38255885
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CTCF boundary remodels chromatin domain and drives aberrant
    Luo H; Wang F; Zha J; Li H; Yan B; Du Q; Yang F; Sobh A; Vulpe C; Drusbosky L; Cogle C; Chepelev I; Xu B; Nimer SD; Licht J; Qiu Y; Chen B; Xu M; Huang S
    Blood; 2018 Aug; 132(8):837-848. PubMed ID: 29760161
    [No Abstract]   [Full Text] [Related]  

  • 16. Prolonged XPO1 inhibition is essential for optimal antileukemic activity in NPM1-mutated AML.
    Pianigiani G; Gagliardi A; Mezzasoma F; Rocchio F; Tini V; Bigerna B; Sportoletti P; Caruso S; Marra A; Peruzzi S; Petito E; Spinozzi G; Shacham S; Landesman Y; Quintarelli C; Gresele P; Locatelli F; Martelli MP; Falini B; Brunetti L
    Blood Adv; 2022 Nov; 6(22):5938-5949. PubMed ID: 36037515
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nucleophosmin mutations in acute myeloid leukemia: a tale of protein unfolding and mislocalization.
    Federici L; Falini B
    Protein Sci; 2013 May; 22(5):545-56. PubMed ID: 23436734
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia.
    Uckelmann HJ; Haarer EL; Takeda R; Wong EM; Hatton C; Marinaccio C; Perner F; Rajput M; Antonissen NJC; Wen Y; Yang L; Brunetti L; Chen CW; Armstrong SA
    Cancer Discov; 2023 Mar; 13(3):746-765. PubMed ID: 36455613
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia.
    Wang XQD; Fan D; Han Q; Liu Y; Miao H; Wang X; Li Q; Chen D; Gore H; Himadewi P; Pfeifer GP; Cierpicki T; Grembecka J; Su J; Chong S; Wan L; Zhang X
    Cancer Discov; 2023 Mar; 13(3):724-745. PubMed ID: 36455589
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oridonin induces NPM mutant protein translocation and apoptosis in NPM1c+ acute myeloid leukemia cells in vitro.
    Li FF; Yi S; Wen L; He J; Yang LJ; Zhao J; Zhang BP; Cui GH; Chen Y
    Acta Pharmacol Sin; 2014 Jun; 35(6):806-13. PubMed ID: 24902788
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.