These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 31832989)

  • 21. Synthesis and biological evaluation of novel indole-pyrazoline hybrid derivatives as potential topoisomerase 1 inhibitors.
    Shu B; Yu Q; Hu DX; Che T; Zhang SS; Li D
    Bioorg Med Chem Lett; 2020 Feb; 30(4):126925. PubMed ID: 31901379
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase I inhibitory properties.
    Lee CC; Chang DM; Huang KF; Chen CL; Chen TC; Lo Y; Guh JH; Huang HS
    Bioorg Med Chem; 2013 Nov; 21(22):7125-33. PubMed ID: 24094433
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
    Kadayat TM; Song C; Shin S; Magar TB; Bist G; Shrestha A; Thapa P; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Jul; 23(13):3499-512. PubMed ID: 26022080
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs.
    Salerno S; Da Settimo F; Taliani S; Simorini F; La Motta C; Fornaciari G; Marini AM
    Curr Med Chem; 2010; 17(35):4270-90. PubMed ID: 20939813
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Catalytic cyclometallation in steroid chemistry III: Synthesis of steroidal derivatives of 5Z,9Z-dienoic acid and investigation of its human topoisomerase I inhibitory activity.
    D'yakonov VA; Dzhemileva LU; Tuktarova RA; Makarov AA; Islamov II; Mulyukova AR; Dzhemilev UM
    Steroids; 2015 Oct; 102():110-7. PubMed ID: 26276106
    [TBL] [Abstract][Full Text] [Related]  

  • 26. New strategies in the discovery of novel non-camptothecin topoisomerase I inhibitors.
    Sheng C; Miao Z; Zhang W
    Curr Med Chem; 2011; 18(28):4389-409. PubMed ID: 21861816
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors.
    Khadka DB; Park S; Jin Y; Han J; Kwon Y; Cho WJ
    Eur J Med Chem; 2018 Jan; 143():200-215. PubMed ID: 29174815
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons.
    Makhey D; Gatto B; Yu C; Liu A; Liu LF; LaVoie EJ
    Bioorg Med Chem; 1996 Jun; 4(6):781-91. PubMed ID: 8818227
    [TBL] [Abstract][Full Text] [Related]  

  • 29. DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin.
    Bailly C; Riou JF; Colson P; Houssier C; Rodrigues-Pereira E; Prudhomme M
    Biochemistry; 1997 Apr; 36(13):3917-29. PubMed ID: 9092822
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I.
    Yu CC; Pan SL; Chao SW; Liu SP; Hsu JL; Yang YC; Li TK; Huang WJ; Guh JH
    Biochem Pharmacol; 2014 Aug; 90(3):320-30. PubMed ID: 24915421
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity.
    Habermeyer M; Fritz J; Barthelmes HU; Christensen MO; Larsen MK; Boege F; Marko D
    Chem Res Toxicol; 2005 Sep; 18(9):1395-404. PubMed ID: 16167831
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors.
    Park S; Hong E; Kwak SY; Jun KY; Lee ES; Kwon Y; Na Y
    Eur J Med Chem; 2016 Nov; 123():211-225. PubMed ID: 27484510
    [TBL] [Abstract][Full Text] [Related]  

  • 33. DNA sequence selectivity of topoisomerases and topoisomerase poisons.
    Capranico G; Binaschi M
    Biochim Biophys Acta; 1998 Oct; 1400(1-3):185-94. PubMed ID: 9748568
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Topoisomerase I/II inhibition by a novel naphthoquinone containing a modified anthracycline ring system.
    Kennedy S; DiCesare JC; Sheaff RJ
    Biochem Biophys Res Commun; 2011 Apr; 408(1):94-8. PubMed ID: 21458415
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Novel synthetic 2-amino-10-(3,5-dimethoxy)benzyl-9(10H)-acridinone derivatives as potent DNA-binding antiproliferative agents.
    Gao C; Liu F; Luan X; Tan C; Liu H; Xie Y; Jin Y; Jiang Y
    Bioorg Med Chem; 2010 Nov; 18(21):7507-14. PubMed ID: 20863710
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and biological evaluation of 1,5-naphthyridines as topoisomerase I inhibitors. A new family of antiproliferative agents.
    Alonso C; Fuertes M; González M; Rodríguez-Gascón A; Rubiales G; Palacios F
    Curr Top Med Chem; 2014; 14(23):2722-8. PubMed ID: 25515747
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and biological assays of 9-(acylamino) homocamptothecins as DNA topoisomerase I inhibitors.
    Guo W; Dong G; Zhu L; Liu W; Zhuang C; Guo Z; Yao J; Sheng C; Zhang H; Miao Z; Zhang W
    Chem Biodivers; 2013 Oct; 10(10):1804-15. PubMed ID: 24130024
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs.
    Baechler SA; Fehr M; Habermeyer M; Hofmann A; Merz KH; Fiebig HH; Marko D; Eisenbrand G
    Bioorg Med Chem; 2013 Feb; 21(3):814-23. PubMed ID: 23266176
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
    Bailly C; Lansiaux A; Dassonneville L; Demarquay D; Coulomb H; Huchet M; Lavergne O; Bigg DC
    Biochemistry; 1999 Nov; 38(47):15556-63. PubMed ID: 10569939
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [Poisons of DNA topoisomerases I and II].
    Charcosset JY; Soues S; Laval F
    Bull Cancer; 1993 Nov; 80(11):923-54. PubMed ID: 8081034
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.