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2. Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile. Giannikou K; Zhu Z; Kim J; Winden KD; Tyburczy ME; Marron D; Parker JS; Hebert Z; Bongaarts A; Taing L; Long HW; Pisano WV; Alexandrescu S; Godlewski B; Nellist M; Kotulska K; Jozwiak S; Roszkowski M; Mandera M; Thiele EA; Lidov H; Getz G; Devinsky O; Lawrence MS; Ligon KL; Ellison DW; Sahin M; Aronica E; Meredith DM; Kwiatkowski DJ Mod Pathol; 2021 Feb; 34(2):264-279. PubMed ID: 33051600 [TBL] [Abstract][Full Text] [Related]
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4. Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation. Chan JA; Zhang H; Roberts PS; Jozwiak S; Wieslawa G; Lewin-Kowalik J; Kotulska K; Kwiatkowski DJ J Neuropathol Exp Neurol; 2004 Dec; 63(12):1236-42. PubMed ID: 15624760 [TBL] [Abstract][Full Text] [Related]
10. Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures. van Scheppingen J; Iyer AM; Prabowo AS; Mühlebner A; Anink JJ; Scholl T; Feucht M; Jansen FE; Spliet WG; Krsek P; Zamecnik J; Buccoliero AM; Giordano F; Genitori L; Kotulska K; Jozwiak S; Jaworski J; Liszewska E; van Vliet EA; Aronica E Glia; 2016 Jun; 64(6):1066-82. PubMed ID: 27014996 [TBL] [Abstract][Full Text] [Related]
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12. Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt. Zordan P; Cominelli M; Cascino F; Tratta E; Poliani PL; Galli R J Clin Invest; 2018 Apr; 128(4):1688-1706. PubMed ID: 29389670 [TBL] [Abstract][Full Text] [Related]
13. Identification of TSC1 or TSC2 mutation limited to the tumor in three cases of solitary subependymal giant cell astrocytoma using next-generation sequencing technology. Fohlen M; Harzallah I; Polivka M; Giuliano F; Pons L; Streichenberger N; Dorfmüller G; Touraine R Childs Nerv Syst; 2020 May; 36(5):961-965. PubMed ID: 32103336 [TBL] [Abstract][Full Text] [Related]
14. Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications. Tyburczy ME; Kotulska K; Pokarowski P; Mieczkowski J; Kucharska J; Grajkowska W; Roszkowski M; Jozwiak S; Kaminska B Am J Pathol; 2010 Apr; 176(4):1878-90. PubMed ID: 20133820 [TBL] [Abstract][Full Text] [Related]
15. Unique findings of subependymal giant cell astrocytoma within cortical tubers in patients with tuberous sclerosis complex: a histopathological evaluation. Katz JS; Frankel H; Ma T; Zagzag D; Liechty B; Zeev BB; Tzadok M; Devinsky O; Weiner HL; Roth J Childs Nerv Syst; 2017 Apr; 33(4):601-607. PubMed ID: 28074282 [TBL] [Abstract][Full Text] [Related]
16. TSC2 somatic mosaic mutation, including extra-tumor tissue, may be the developmental cause of solitary subependymal giant cell astrocytoma. Sasaki T; Uda T; Kuki I; Kunihiro N; Okazaki S; Niida Y; Goto T Childs Nerv Syst; 2022 Jan; 38(1):77-83. PubMed ID: 34741623 [TBL] [Abstract][Full Text] [Related]
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19. Solitary subependymal giant cell astrocytoma: Case report and review of the literature. Corlette L; Reid A; Roberts-Thomson S; Christie M; Gaillard F J Clin Neurosci; 2020 Dec; 82(Pt A):26-28. PubMed ID: 33317733 [TBL] [Abstract][Full Text] [Related]
20. Congenital subependymal giant cell astrocytomas in patients with tuberous sclerosis complex. Kotulska K; Borkowska J; Mandera M; Roszkowski M; Jurkiewicz E; Grajkowska W; Bilska M; Jóźwiak S Childs Nerv Syst; 2014 Dec; 30(12):2037-42. PubMed ID: 25227171 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]