BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 31836452)

  • 1. Time-dependent enzyme inactivation: Numerical analyses of in vitro data and prediction of drug-drug interactions.
    Yadav J; Paragas E; Korzekwa K; Nagar S
    Pharmacol Ther; 2020 Feb; 206():107449. PubMed ID: 31836452
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.
    Korzekwa K; Tweedie D; Argikar UA; Whitcher-Johnstone A; Bell L; Bickford S; Nagar S
    Drug Metab Dispos; 2014 Sep; 42(9):1587-95. PubMed ID: 24939653
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A numerical method for analysis of in vitro time-dependent inhibition data. Part 1. Theoretical considerations.
    Nagar S; Jones JP; Korzekwa K
    Drug Metab Dispos; 2014 Sep; 42(9):1575-86. PubMed ID: 24939654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Improved Predictions of Drug-Drug Interactions Mediated by Time-Dependent Inhibition of CYP3A.
    Yadav J; Korzekwa K; Nagar S
    Mol Pharm; 2018 May; 15(5):1979-1995. PubMed ID: 29608318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dynamic and Static Simulations of Fluvoxamine-Perpetrated Drug-Drug Interactions Using Multiple Cytochrome P450 Inhibition Modeling, and Determination of Perpetrator-Specific CYP Isoform Inhibition Constants and Fractional CYP Isoform Contributions to Victim Clearance.
    Iga K
    J Pharm Sci; 2016 Mar; 105(3):1307-17. PubMed ID: 26886336
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Atypical Michaelis-Menten kinetics in cytochrome P450 enzymes: A focus on substrate inhibition.
    Leow JWH; Chan ECY
    Biochem Pharmacol; 2019 Nov; 169():113615. PubMed ID: 31445022
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cocktail-substrate approach-based high-throughput assay for evaluation of direct and time-dependent inhibition of multiple cytochrome P450 isoforms.
    Kozakai K; Yamada Y; Oshikata M; Kawase T; Suzuki E; Haramaki Y; Taniguchi H
    Drug Metab Pharmacokinet; 2014; 29(2):198-207. PubMed ID: 24172718
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of metabolites in predicting drug-drug interactions: focus on irreversible cytochrome P450 inhibition.
    VandenBrink BM; Isoherranen N
    Curr Opin Drug Discov Devel; 2010 Jan; 13(1):66-77. PubMed ID: 20047147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High-throughput cytochrome P450 loss and metabolic intermediate complex assays to aid in designing out of CYP3A inactivation.
    Russell DA; Cerny MA
    Methods Enzymol; 2023; 690():341-368. PubMed ID: 37858534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development and validation of an in vitro, seven-in-one human cytochrome P450 assay for evaluation of both direct and time-dependent inhibition.
    Dahlinger D; Duechting S; Nuecken D; Sydow K; Fuhr U; Frechen S
    J Pharmacol Toxicol Methods; 2016; 77():66-75. PubMed ID: 26528794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enzyme kinetics for clinically relevant CYP inhibition.
    Zhang ZY; Wong YN
    Curr Drug Metab; 2005 Jun; 6(3):241-57. PubMed ID: 15975042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Vitro Assessment of Potential for CYP-Inhibition-Based Drug-Drug Interaction Between Vonoprazan and Clopidogrel.
    Nishihara M; Yamasaki H; Czerniak R; Jenkins H
    Eur J Drug Metab Pharmacokinet; 2019 Apr; 44(2):217-227. PubMed ID: 30361928
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Translational aspects of cytochrome P450-mediated drug-drug interactions: A case study with clopidogrel.
    Tornio A; Filppula AM; Backman JT
    Basic Clin Pharmacol Toxicol; 2022 Jan; 130 Suppl 1():48-59. PubMed ID: 34410044
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The current status of time dependent CYP inhibition assay and in silico drug-drug interaction predictions.
    Yan Z; Caldwell GW
    Curr Top Med Chem; 2012; 12(11):1291-7. PubMed ID: 22571791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Non-Michaelis-Menten kinetics in cytochrome P450-catalyzed reactions.
    Atkins WM
    Annu Rev Pharmacol Toxicol; 2005; 45():291-310. PubMed ID: 15832445
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition and induction of cytochrome P450 and the clinical implications.
    Lin JH; Lu AY
    Clin Pharmacokinet; 1998 Nov; 35(5):361-90. PubMed ID: 9839089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drug-drug interaction potential of marketed oncology drugs: in vitro assessment of time-dependent cytochrome P450 inhibition, reactive metabolite formation and drug-drug interaction prediction.
    Kenny JR; Mukadam S; Zhang C; Tay S; Collins C; Galetin A; Khojasteh SC
    Pharm Res; 2012 Jul; 29(7):1960-76. PubMed ID: 22415140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytochrome P450 time-dependent inhibition and induction: advances in assays, risk analysis and modelling.
    Riley RJ; Wilson CE
    Expert Opin Drug Metab Toxicol; 2015 Apr; 11(4):557-72. PubMed ID: 25659570
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prediction of drug-drug interactions arising from mechanism-based inactivation: key input parameters and impact on risk assessment.
    Wong SG
    Curr Drug Metab; 2011 Nov; 12(9):871-90. PubMed ID: 21619522
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Drug-drug interactions via mechanism-based cytochrome P450 inactivation: points to consider for risk assessment from in vitro data and clinical pharmacologic evaluation.
    Venkatakrishnan K; Obach RS
    Curr Drug Metab; 2007 Jun; 8(5):449-62. PubMed ID: 17584016
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.