BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 31838898)

  • 21. Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment.
    Montanari S; Mahmoud AM; Pruccoli L; Rabbito A; Naldi M; Petralla S; Moraleda I; Bartolini M; Monti B; Iriepa I; Belluti F; Gobbi S; Di Marzo V; Bisi A; Tarozzi A; Ligresti A; Rampa A
    Eur J Med Chem; 2019 Sep; 178():243-258. PubMed ID: 31185414
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Benzo[d]thiazol-2(3H)-ones as new potent selective CB
    Leleu-Chavain N; Baudelet D; Heloire VM; Rocha DE; Renault N; Barczyk A; Djouina M; Body-Malapel M; Carato P; Millet R
    Eur J Med Chem; 2019 Mar; 165():347-362. PubMed ID: 30583970
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation.
    Yang P; Wang L; Feng R; Almehizia AA; Tong Q; Myint KZ; Ouyang Q; Alqarni MH; Wang L; Xie XQ
    J Med Chem; 2013 Mar; 56(5):2045-58. PubMed ID: 23406429
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Fenchone Derivatives as a Novel Class of CB2 Selective Ligands: Design, Synthesis, X-ray Structure and Therapeutic Potential.
    Smoum R; Haj C; Hirsch S; Nemirovski A; Yekhtin Z; Bogoslavsky B; Bakshi GK; Chourasia M; Gallily R; Tam J; Mechoulam R
    Molecules; 2022 Feb; 27(4):. PubMed ID: 35209170
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis.
    Shi Y; Duan YH; Ji YY; Wang ZL; Wu YR; Gunosewoyo H; Xie XY; Chen JZ; Yang F; Li J; Tang J; Xie X; Yu LF
    J Med Chem; 2017 Aug; 60(16):7067-7083. PubMed ID: 28726401
    [TBL] [Abstract][Full Text] [Related]  

  • 26. 2,3-Dihydro-1-benzofuran derivatives as a series of potent selective cannabinoid receptor 2 agonists: design, synthesis, and binding mode prediction through ligand-steered modeling.
    Diaz P; Phatak SS; Xu J; Fronczek FR; Astruc-Diaz F; Thompson CM; Cavasotto CN; Naguib M
    ChemMedChem; 2009 Oct; 4(10):1615-29. PubMed ID: 19637157
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium.
    Kimball ES; Schneider CR; Wallace NH; Hornby PJ
    Am J Physiol Gastrointest Liver Physiol; 2006 Aug; 291(2):G364-71. PubMed ID: 16574988
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-
    Mugnaini C; Kostrzewa M; Bryk M; Mahmoud AM; Brizzi A; Lamponi S; Giorgi G; Ferlenghi F; Vacondio F; Maccioni P; Colombo G; Mor M; Starowicz K; Di Marzo V; Ligresti A; Corelli F
    J Med Chem; 2020 Jul; 63(13):7369-7391. PubMed ID: 32515588
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (SAB378), a peripherally restricted cannabinoid CB1/CB2 receptor agonist, inhibits gastrointestinal motility but has no effect on experimental colitis in mice.
    Cluny NL; Keenan CM; Duncan M; Fox A; Lutz B; Sharkey KA
    J Pharmacol Exp Ther; 2010 Sep; 334(3):973-80. PubMed ID: 20571060
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile.
    Silvestri R; Ligresti A; La Regina G; Piscitelli F; Gatti V; Brizzi A; Pasquini S; Lavecchia A; Allarà M; Fantini N; Carai MA; Novellino E; Colombo G; Di Marzo V; Corelli F
    Bioorg Med Chem; 2009 Aug; 17(15):5549-64. PubMed ID: 19595596
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Decahydroquinoline amides as highly selective CB2 agonists: role of selectivity on in vivo efficacy in a rodent model of analgesia.
    Manley PJ; Zartman A; Paone DV; Burgey CS; Henze DA; Della Penna K; Desai R; Leitl MD; Lemaire W; White RB; Yeh S; Urban MO; Kane SA; Hartman GD; Bilodeau MT; Trotter BW
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2359-64. PubMed ID: 21420857
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB
    Navarro G; Gonzalez A; Sánchez-Morales A; Casajuana-Martin N; Gómez-Ventura M; Cordomí A; Busqué F; Alibés R; Pardo L; Franco R
    J Med Chem; 2021 Jul; 64(13):9354-9364. PubMed ID: 34161090
    [TBL] [Abstract][Full Text] [Related]  

  • 33. 7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists.
    Rempel V; Volz N; Hinz S; Karcz T; Meliciani I; Nieger M; Wenzel W; Bräse S; Müller CE
    J Med Chem; 2012 Sep; 55(18):7967-77. PubMed ID: 22916707
    [TBL] [Abstract][Full Text] [Related]  

  • 34. 1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor.
    Lucchesi V; Parkkari T; Savinainen JR; Malfitano AM; Allarà M; Bertini S; Castelli F; Del Carlo S; Laezza C; Ligresti A; Saccomanni G; Bifulco M; Di Marzo V; Macchia M; Manera C
    Eur J Med Chem; 2014 Mar; 74():524-32. PubMed ID: 24518874
    [TBL] [Abstract][Full Text] [Related]  

  • 35. MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models.
    Naguib M; Diaz P; Xu JJ; Astruc-Diaz F; Craig S; Vivas-Mejia P; Brown DL
    Br J Pharmacol; 2008 Dec; 155(7):1104-16. PubMed ID: 18846037
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Effects of Cannabinoid Agonists and Antagonists on Sleep and Breathing in Sprague-Dawley Rats.
    Calik MW; Carley DW
    Sleep; 2017 Sep; 40(9):. PubMed ID: 28934522
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist.
    Brizzi A; Aiello F; Marini P; Cascio MG; Corelli F; Brizzi V; De Petrocellis L; Ligresti A; Luongo L; Lamponi S; Maione S; Pertwee RG; Di Marzo V
    Bioorg Med Chem; 2014 Sep; 22(17):4770-83. PubMed ID: 25065940
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 6-Methoxy-N-alkyl isatin acylhydrazone derivatives as a novel series of potent selective cannabinoid receptor 2 inverse agonists: design, synthesis, and binding mode prediction.
    Diaz P; Phatak SS; Xu J; Astruc-Diaz F; Cavasotto CN; Naguib M
    J Med Chem; 2009 Jan; 52(2):433-44. PubMed ID: 19115816
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability.
    Harvey BS; Nicotra LL; Vu M; Smid SD
    Cytokine; 2013 Aug; 63(2):209-17. PubMed ID: 23706402
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and SAR evaluation of coumarin derivatives as potent cannabinoid receptor agonists.
    Mohr F; Hurrle T; Burggraaff L; Langer L; Bemelmans MP; Knab M; Nieger M; van Westen GJP; Heitman LH; Bräse S
    Eur J Med Chem; 2021 Aug; 220():113354. PubMed ID: 33915369
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.