BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 31841125)

  • 1. Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.
    Lau A; Avery DT; Jackson K; Lenthall H; Volpi S; Brigden H; Russell AJ; Bier J; Reed JH; Smart JM; Cole T; Choo S; Gray PE; Berglund LJ; Hsu P; Wong M; O'Sullivan M; Boztug K; Meyts I; Uzel G; Notarangelo LD; Brink R; Goodnow CC; Tangye SG; Deenick EK
    J Exp Med; 2020 Feb; 217(2):. PubMed ID: 31841125
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peripheral Tolerance Checkpoints Imposed by Ubiquitous Antigen Expression Limit Antigen-Specific B Cell Responses under Strongly Immunogenic Conditions.
    Brooks JF; Murphy PR; Barber JEM; Wells JW; Steptoe RJ
    J Immunol; 2020 Sep; 205(5):1239-1247. PubMed ID: 32709661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of WASp and N-WASp in B cells cripples the germinal center response and results in production of IgM autoantibodies.
    Dahlberg CI; Torres ML; Petersen SH; Baptista MA; Keszei M; Volpi S; Grasset EK; Karlsson MC; Walter JE; Snapper SB; Notarangelo LD; Westerberg LS
    J Autoimmun; 2015 Aug; 62():81-92. PubMed ID: 26143192
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Self-Reactive B Cells in the Germinal Center Reaction.
    Brink R; Phan TG
    Annu Rev Immunol; 2018 Apr; 36():339-357. PubMed ID: 29356584
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of dysregulated PI3Kdelta signaling in human autoimmunity.
    Bier J; Deenick EK
    Immunol Rev; 2022 May; 307(1):134-144. PubMed ID: 35092042
    [TBL] [Abstract][Full Text] [Related]  

  • 6. B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation.
    William J; Euler C; Primarolo N; Shlomchik MJ
    J Immunol; 2006 Feb; 176(4):2142-51. PubMed ID: 16455970
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An apoptosis-dependent checkpoint for autoimmunity in memory B and plasma cells.
    Mayer CT; Nieke JP; Gazumyan A; Cipolla M; Wang Q; Oliveira TY; Ramos V; Monette S; Li QZ; Gershwin ME; Kashkar H; Nussenzweig MC
    Proc Natl Acad Sci U S A; 2020 Oct; 117(40):24957-24963. PubMed ID: 32963096
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tolerance through indifference: autoreactive B cells to the nuclear antigen La show no evidence of tolerance in a transgenic model.
    Aplin BD; Keech CL; de Kauwe AL; Gordon TP; Cavill D; McCluskey J
    J Immunol; 2003 Dec; 171(11):5890-900. PubMed ID: 14634099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interleukin-33 Contributes Toward Loss of Tolerance by Promoting B-Cell-Activating Factor of the Tumor-Necrosis-Factor Family (BAFF)-Dependent Autoantibody Production.
    Rose WA; Okragly AJ; Hu NN; Daniels MR; Martin AP; Koh YT; Kikly K; Benschop RJ
    Front Immunol; 2018; 9():2871. PubMed ID: 30574145
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.
    Chan TD; Wood K; Hermes JR; Butt D; Jolly CJ; Basten A; Brink R
    Immunity; 2012 Nov; 37(5):893-904. PubMed ID: 23142780
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity.
    Burnett DL; Reed JH; Christ D; Goodnow CC
    Immunol Rev; 2019 Nov; 292(1):61-75. PubMed ID: 31556969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints.
    Vuyyuru R; Mohan C; Manser T; Rahman ZS
    J Immunol; 2009 Nov; 183(9):5716-27. PubMed ID: 19828626
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clonal Evolution of Autoreactive Germinal Centers.
    Degn SE; van der Poel CE; Firl DJ; Ayoglu B; Al Qureshah FA; Bajic G; Mesin L; Reynaud CA; Weill JC; Utz PJ; Victora GD; Carroll MC
    Cell; 2017 Aug; 170(5):913-926.e19. PubMed ID: 28841417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Germline-activating mutations in
    Avery DT; Kane A; Nguyen T; Lau A; Nguyen A; Lenthall H; Payne K; Shi W; Brigden H; French E; Bier J; Hermes JR; Zahra D; Sewell WA; Butt D; Elliott M; Boztug K; Meyts I; Choo S; Hsu P; Wong M; Berglund LJ; Gray P; O'Sullivan M; Cole T; Holland SM; Ma CS; Burkhart C; Corcoran LM; Phan TG; Brink R; Uzel G; Deenick EK; Tangye SG
    J Exp Med; 2018 Aug; 215(8):2073-2095. PubMed ID: 30018075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PI3K pathway defects leading to immunodeficiency and immune dysregulation.
    Nunes-Santos CJ; Uzel G; Rosenzweig SD
    J Allergy Clin Immunol; 2019 May; 143(5):1676-1687. PubMed ID: 31060715
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens.
    Liu S; Velez MG; Humann J; Rowland S; Conrad FJ; Halverson R; Torres RM; Pelanda R
    J Immunol; 2005 Oct; 175(8):5067-76. PubMed ID: 16210610
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity.
    Preite S; Huang B; Cannons JL; McGavern DB; Schwartzberg PL
    Front Immunol; 2018; 9():3079. PubMed ID: 30666254
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Active PI3K abrogates central tolerance in high-avidity autoreactive B cells.
    Greaves SA; Peterson JN; Strauch P; Torres RM; Pelanda R
    J Exp Med; 2019 May; 216(5):1135-1153. PubMed ID: 30948496
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphatidylinositol 3-kinase (PI3K) signaling and regulation of the antibody response.
    Omori SA; Rickert RC
    Cell Cycle; 2007 Feb; 6(4):397-402. PubMed ID: 17312395
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Surrogate light chain is required for central and peripheral B-cell tolerance and inhibits anti-DNA antibody production by marginal zone B cells.
    Ren W; Grimsholm O; Bernardi AI; Höök N; Stern A; Cavallini N; Mårtensson IL
    Eur J Immunol; 2015 Apr; 45(4):1228-37. PubMed ID: 25546233
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.