These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 31841273)

  • 1. Methods for Estimating the Probability of Clonality in Cell Line Development.
    Chen C; Le K; Le H; Daris K; Soice N; Stevens J; Goudar CT
    Biotechnol J; 2020 Feb; 15(2):e1900289. PubMed ID: 31841273
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Implementation of Plate Imaging for Demonstration of Monoclonality in Biologics Manufacturing Development.
    Zingaro K; Shaw D; Carson J; Mayer-Bartschmid A; Bender C; Alves C; Mcvey D; Qian NX; Wei Q; Laird MW; Zhu Y; Emmins R; Follit JA; Porter A; Racher AJ; Milne S; Carubelli I; Du Z; Khatri A; Failly M; Broly H; Lee F; Reeser M; Spidel J; Anderson K; Demaria C; Di-Carlo J; Gill J; Lundquist A; Kumar SR; Gill T
    PDA J Pharm Sci Technol; 2018; 72(4):438-450. PubMed ID: 29669815
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not.
    Zhou Y; Shaw D; Lam C; Tsukuda J; Yim M; Tang D; Louie S; Laird MW; Snedecor B; Misaghi S
    Biotechnol Prog; 2018 May; 34(3):559-569. PubMed ID: 28941017
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A single-step FACS sorting strategy in conjunction with fluorescent vital dye imaging efficiently assures clonality of biopharmaceutical production cell lines.
    Fieder J; Schulz P; Gorr I; Bradl H; Wenger T
    Biotechnol J; 2017 Jun; 12(6):. PubMed ID: 28371300
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Achieving greater efficiency and higher confidence in single-cell cloning by combining cell printing and plate imaging technologies.
    Yim M; Shaw D
    Biotechnol Prog; 2018 Nov; 34(6):1454-1459. PubMed ID: 30281954
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Considering "clonality": A regulatory perspective on the importance of the clonal derivation of mammalian cell banks in biopharmaceutical development.
    Welch JT; Arden NS
    Biologicals; 2019 Nov; 62():16-21. PubMed ID: 31588011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Measuring the aggregation of CHO cells prior to single cell cloning allows a more accurate determination of the probability of clonality.
    Klottrup KJ; Miro-Quesada G; Flack L; Pereda I; Hawley-Nelson P
    Biotechnol Prog; 2018 May; 34(3):593-601. PubMed ID: 28556621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development and characterization of an automated imaging workflow to generate clonally-derived cell lines for therapeutic proteins.
    Shaw D; Yim M; Tsukuda J; Joly JC; Lin A; Snedecor B; Laird MW; Lang SE
    Biotechnol Prog; 2018 May; 34(3):584-592. PubMed ID: 28960825
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coupling picodroplet microfluidics with plate imaging for the rapid creation of biomanufacturing suitable cell lines with high probability and improved multi-step assurance of monoclonality.
    Pybus LP; Kalsi D; Matthews JT; Hawke E; Barber N; Richer R; Young A; Saunders FL
    Biotechnol J; 2022 Jan; 17(1):e2100357. PubMed ID: 34633760
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genome-wide analysis of single nucleotide variants allows for robust and accurate assessment of clonal derivation in cell lines used to produce biologics.
    Kuhn A; Le Fourn V; Fisch I; Mermod N
    Biotechnol Bioeng; 2020 Dec; 117(12):3628-3638. PubMed ID: 32779734
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Assurance of monoclonality in one round of cloning through cell sorting for single cell deposition coupled with high resolution cell imaging.
    Evans K; Albanetti T; Venkat R; Schoner R; Savery J; Miro-Quesada G; Rajan B; Groves C
    Biotechnol Prog; 2015; 31(5):1172-8. PubMed ID: 26195345
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of monoclonality of cell lines from sequential dilution assays.
    Koziol JA; Ferrari C; Chisari FV
    J Immunol Methods; 1987 Dec; 105(1):139-43. PubMed ID: 3500238
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality.
    Ko P; Misaghi S; Hu Z; Zhan D; Tsukuda J; Yim M; Sanford M; Shaw D; Shiratori M; Snedecor B; Laird M; Shen A
    Biotechnol Prog; 2018 May; 34(3):624-634. PubMed ID: 29226566
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line.
    Tharmalingam T; Barkhordarian H; Tejeda N; Daris K; Yaghmour S; Yam P; Lu F; Goudar C; Munro T; Stevens J
    Biotechnol Prog; 2018 May; 34(3):613-623. PubMed ID: 29882350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cloned genes, goats, and the future of the biopharm.
    Nat Biotechnol; 1999 May; 17(5):405. PubMed ID: 10331777
    [No Abstract]   [Full Text] [Related]  

  • 16. Industry view on the relative importance of "clonality" of biopharmaceutical-producing cell lines.
    Frye C; Deshpande R; Estes S; Francissen K; Joly J; Lubiniecki A; Munro T; Russell R; Wang T; Anderson K
    Biologicals; 2016 Mar; 44(2):117-22. PubMed ID: 26852257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Murphy's law of limiting dilution cloning.
    Staszewski R
    Stat Med; 1990 Apr; 9(4):457-61. PubMed ID: 2362981
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transgenic mammalian species, generated by somatic cell cloning, in biomedicine, biopharmaceutical industry and human nutrition/dietetics--recent achievements.
    Samiec M; Skrzyszowska M
    Pol J Vet Sci; 2011; 14(2):317-28. PubMed ID: 21721422
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assuring Clonality on the Beacon Digital Cell Line Development Platform.
    Le K; Tan C; Le H; Tat J; Zasadzinska E; Diep J; Zastrow R; Chen C; Stevens J
    Biotechnol J; 2020 Jan; 15(1):e1900247. PubMed ID: 31743597
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Understanding biopharmaceutical production at single nucleotide resolution using ribosome footprint profiling.
    Tzani I; Monger C; Kelly P; Barron N; Kelly RM; Clarke C
    Curr Opin Biotechnol; 2018 Oct; 53():182-190. PubMed ID: 29471208
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.