BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 31852846)

  • 1. Immunomodulatory activity of humanized anti-IL-7R monoclonal antibody RN168 in subjects with type 1 diabetes.
    Herold KC; Bucktrout SL; Wang X; Bode BW; Gitelman SE; Gottlieb PA; Hughes J; Joh T; McGill JB; Pettus JH; Potluri S; Schatz D; Shannon M; Udata C; Wong G; Levisetti M; Ganguly BJ; Garzone PD;
    JCI Insight; 2019 Dec; 4(24):. PubMed ID: 31852846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interleukin-7 promotes the survival of human CD4+ effector/memory T cells by up-regulating Bcl-2 proteins and activating the JAK/STAT signalling pathway.
    Chetoui N; Boisvert M; Gendron S; Aoudjit F
    Immunology; 2010 Jul; 130(3):418-26. PubMed ID: 20465565
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice.
    Vazquez-Mateo C; Collins J; Fleury M; Dooms H
    BMC Immunol; 2017 Mar; 18(1):18. PubMed ID: 28356069
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Model-Based Characterization of the Pharmacokinetics, Target Engagement Biomarkers, and Immunomodulatory Activity of PF-06342674, a Humanized mAb Against IL-7 Receptor-α, in Adults with Type 1 Diabetes.
    Williams JH; Udata C; Ganguly BJ; Bucktrout SL; Joh T; Shannon M; Wong GY; Levisetti M; Garzone PD; Meng X
    AAPS J; 2020 Jan; 22(2):23. PubMed ID: 31900603
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients.
    Rigby MR; Harris KM; Pinckney A; DiMeglio LA; Rendell MS; Felner EI; Dostou JM; Gitelman SE; Griffin KJ; Tsalikian E; Gottlieb PA; Greenbaum CJ; Sherry NA; Moore WV; Monzavi R; Willi SM; Raskin P; Keyes-Elstein L; Long SA; Kanaparthi S; Lim N; Phippard D; Soppe CL; Fitzgibbon ML; McNamara J; Nepom GT; Ehlers MR
    J Clin Invest; 2015 Aug; 125(8):3285-96. PubMed ID: 26193635
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of naive and memory T cells by interleukin-15.
    Kanegane H; Tosato G
    Blood; 1996 Jul; 88(1):230-5. PubMed ID: 8704178
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CD4
    Seyfarth J; Mütze N; Antony Cruz J; Kummer S; Reinauer C; Mayatepek E; Meissner T; Jacobsen M
    Front Immunol; 2019; 10():820. PubMed ID: 31110501
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin 7 receptor alpha as a potential therapeutic target in transplantation.
    Racapé M; Vanhove B; Soulillou JP; Brouard S
    Arch Immunol Ther Exp (Warsz); 2009; 57(4):253-61. PubMed ID: 19585222
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dominant TNFα and impaired IL-2 cytokine profiles of CD4
    Seyfarth J; Förtsch K; Ahlert H; Laws HJ; Karges B; Deenen R; Köhrer K; Mayatepek E; Meissner T; Jacobsen M
    Immunol Cell Biol; 2017 Aug; 95(7):630-639. PubMed ID: 28377612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human CD4(+) effector T lymphocytes generated upon TCR engagement with self-peptides respond defectively to IL-7 in their transition to memory cells.
    González-Pérez G; Segovia NC; Rivas-Carvalho A; Reyes DP; Torres-Aguilar H; Aguilar-Ruiz SR; Irles C; Soldevila G; Sánchez-Torres C
    Cell Mol Immunol; 2013 May; 10(3):261-74. PubMed ID: 23454917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes.
    Long SA; Thorpe J; Herold KC; Ehlers M; Sanda S; Lim N; Linsley PS; Nepom GT; Harris KM
    Cell Immunol; 2017 Sep; 319():3-9. PubMed ID: 28844471
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Non-redundant role for IL-7R signaling for the survival of CD8+ memory T cells.
    Carrio R; Rolle CE; Malek TR
    Eur J Immunol; 2007 Nov; 37(11):3078-88. PubMed ID: 17935075
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Costimulation Blockade Disrupts CD4
    Eichmann M; Baptista R; Ellis RJ; Heck S; Peakman M; Beam CA
    J Immunol; 2020 Jun; 204(12):3129-3138. PubMed ID: 32404353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence.
    Golden-Mason L; Burton JR; Castelblanco N; Klarquist J; Benlloch S; Wang C; Rosen HR
    Hepatology; 2006 Nov; 44(5):1098-109. PubMed ID: 17058243
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Long-lasting immune responses 4 years after GAD-alum treatment in children with type 1 diabetes.
    Axelsson S; Chéramy M; Hjorth M; Pihl M; Akerman L; Martinuzzi E; Mallone R; Ludvigsson J; Casas R
    PLoS One; 2011; 6(12):e29008. PubMed ID: 22174945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immune reconstitution in HIV+ subjects on lopinavir/ritonavir-based HAART according to the severity of pre-therapy CD4+.
    Marchetti G; Merlini E; Sinigaglia E; Iannotti N; Bai F; Savoldi A; Tincati C; Carpani G; Bini T; Arminio Monforte A
    Curr HIV Res; 2012 Oct; 10(7):597-605. PubMed ID: 22716104
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploiting differential expression of the IL-7 receptor on memory T cells to modulate immune responses.
    Zaunders JJ; Lévy Y; Seddiki N
    Cytokine Growth Factor Rev; 2014 Aug; 25(4):391-401. PubMed ID: 25130296
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-IL-7 receptor α monoclonal antibody (GSK2618960) in healthy subjects - a randomized, double-blind, placebo-controlled study.
    Ellis J; van Maurik A; Fortunato L; Gisbert S; Chen K; Schwartz A; McHugh S; Want A; Santos Franco S; Oliveira JJ; Price J; Coles A; Brown K; Su D; Craigen JL; Yang J; Brett S; Davis B; Cheriyan J; Kousin-Ezewu O; Gray F; Thompson PW; Fernando D
    Br J Clin Pharmacol; 2019 Feb; 85(2):304-315. PubMed ID: 30161291
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dual roles of IL-15 in maintaining IL-7RalphalowCCR7- memory CD8+ T cells in humans via recovering the phosphatidylinositol 3-kinase/AKT pathway.
    Kim HR; Hwang KA; Kang I
    J Immunol; 2007 Nov; 179(10):6734-40. PubMed ID: 17982063
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques.
    Villinger F; Miller R; Mori K; Mayne AE; Bostik P; Sundstrom JB; Sugimoto C; Ansari AA
    Vaccine; 2004 Sep; 22(25-26):3510-21. PubMed ID: 15308379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.