BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 31866563)

  • 1. The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4.
    Thiesen L; Belew ZM; Griem-Krey N; Pedersen SF; Crocoll C; Nour-Eldin HH; Wellendorph P
    Eur J Pharm Sci; 2020 Feb; 143():105203. PubMed ID: 31866563
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In Vitro and In Vivo Evidence for Active Brain Uptake of the GHB Analog HOCPCA by the Monocarboxylate Transporter Subtype 1.
    Thiesen L; Kehler J; Clausen RP; Frølund B; Bundgaard C; Wellendorph P
    J Pharmacol Exp Ther; 2015 Aug; 354(2):166-74. PubMed ID: 25986445
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells.
    Wang Q; Morris ME
    Drug Metab Dispos; 2007 Aug; 35(8):1393-9. PubMed ID: 17502341
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The drug of abuse gamma-hydroxybutyrate is a substrate for sodium-coupled monocarboxylate transporter (SMCT) 1 (SLC5A8): characterization of SMCT-mediated uptake and inhibition.
    Cui D; Morris ME
    Drug Metab Dispos; 2009 Jul; 37(7):1404-10. PubMed ID: 19389857
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantitative autoradiographic analysis of the new radioligand [(3)H](2E)-(5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid ([(3)H]NCS-382) at gamma-hydroxybutyric acid (GHB) binding sites in rat brain.
    Gould GG; Mehta AK; Frazer A; Ticku MK
    Brain Res; 2003 Jul; 979(1-2):51-6. PubMed ID: 12850570
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Drug of Abuse Gamma-Hydroxybutyric Acid Exhibits Tissue-Specific Nonlinear Distribution.
    Felmlee MA; Morse BL; Follman KE; Morris ME
    AAPS J; 2017 Dec; 20(1):21. PubMed ID: 29280004
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Binding characteristics of the gamma-hydroxybutyric acid receptor antagonist [(3)H](2E)-(5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid in the rat brain.
    Mehta AK; Muschaweck NM; Maeda DY; Coop A; Ticku MK
    J Pharmacol Exp Ther; 2001 Dec; 299(3):1148-53. PubMed ID: 11714906
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intracellular and extracellular carbonic anhydrases cooperate non-enzymatically to enhance activity of monocarboxylate transporters.
    Klier M; Andes FT; Deitmer JW; Becker HM
    J Biol Chem; 2014 Jan; 289(5):2765-75. PubMed ID: 24338019
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transport of gamma-hydroxybutyrate in rat kidney membrane vesicles: Role of monocarboxylate transporters.
    Wang Q; Darling IM; Morris ME
    J Pharmacol Exp Ther; 2006 Aug; 318(2):751-61. PubMed ID: 16707723
    [TBL] [Abstract][Full Text] [Related]  

  • 10.
    Rodriguez-Cruz V; Morris ME
    J Pharmacol Exp Ther; 2021 Jul; 378(1):42-50. PubMed ID: 33963018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lack of evidence for synaptic high-affinity γ-hydroxybutyric acid (GHB) transport in rat brain synaptosomes and 11 Na
    Thiesen L; Frølund B; Wellendorph P
    J Neurochem; 2019 Apr; 149(2):195-210. PubMed ID: 30570143
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.
    Nancolas B; Sessions RB; Halestrap AP
    Biochem J; 2015 Feb; 466(1):177-88. PubMed ID: 25437897
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Monocarboxylate transporter-mediated transport of gamma-hydroxybutyric acid in human intestinal Caco-2 cells.
    Lam WK; Felmlee MA; Morris ME
    Drug Metab Dispos; 2010 Mar; 38(3):441-7. PubMed ID: 19952290
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin.
    Eghorn LF; Hoestgaard-Jensen K; Kongstad KT; Bay T; Higgins D; Frølund B; Wellendorph P
    Eur J Pharmacol; 2014 Oct; 740():570-7. PubMed ID: 24973695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites.
    Wellendorph P; Høg S; Sabbatini P; Pedersen MH; Martiny L; Knudsen GM; Frølund B; Clausen RP; Bräuner-Osborne H
    J Pharmacol Exp Ther; 2010 Nov; 335(2):458-64. PubMed ID: 20696866
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Facilitated lactate transport by MCT1 when coexpressed with the sodium bicarbonate cotransporter (NBC) in Xenopus oocytes.
    Becker HM; Bröer S; Deitmer JW
    Biophys J; 2004 Jan; 86(1 Pt 1):235-47. PubMed ID: 14695265
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monocarboxylate Transporters MCT1 and MCT4 Regulate Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells.
    Kong SC; Nøhr-Nielsen A; Zeeberg K; Reshkin SJ; Hoffmann EK; Novak I; Pedersen SF
    Pancreas; 2016 Aug; 45(7):1036-47. PubMed ID: 26765963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid.
    Morris ME; Felmlee MA
    AAPS J; 2008 Jun; 10(2):311-21. PubMed ID: 18523892
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nonenzymatic augmentation of lactate transport via monocarboxylate transporter isoform 4 by carbonic anhydrase II.
    Becker HM; Klier M; Deitmer JW
    J Membr Biol; 2010 Apr; 234(2):125-35. PubMed ID: 20300744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Monocarboxylate transporter (MCT) mediates the transport of gamma-hydroxybutyrate in human kidney HK-2 cells.
    Wang Q; Lu Y; Morris ME
    Pharm Res; 2007 Jun; 24(6):1067-78. PubMed ID: 17377745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.