BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 31876139)

  • 1. Impact of Field Isolate Identified Nonsynonymous Single Nucleotide Polymorphisms on
    Sosa Y; Egbo D; Akabas MH
    ACS Infect Dis; 2020 Feb; 6(2):205-214. PubMed ID: 31876139
    [No Abstract]   [Full Text] [Related]  

  • 2. Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development.
    Deniskin R; Frame IJ; Sosa Y; Akabas MH
    Int J Parasitol Drugs Drug Resist; 2016 Apr; 6(1):1-11. PubMed ID: 26862473
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites.
    Frame IJ; Deniskin R; Rinderspacher A; Katz F; Deng SX; Moir RD; Adjalley SH; Coburn-Flynn O; Fidock DA; Willis IM; Landry DW; Akabas MH
    ACS Chem Biol; 2015 Mar; 10(3):775-83. PubMed ID: 25602169
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit
    Sosa Y; Deniskin R; Frame IJ; Steiginga MS; Bandyopadhyay D; Graybill TL; Kallal LA; Ouellette MT; Pope AJ; Widdowson KL; Young RJ; Akabas MH
    ACS Infect Dis; 2019 Oct; 5(10):1738-1753. PubMed ID: 31373203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Purine import into malaria parasites as a target for antimalarial drug development.
    Frame IJ; Deniskin R; Arora A; Akabas MH
    Ann N Y Acad Sci; 2015 Apr; 1342(1):19-28. PubMed ID: 25424653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1.
    Riegelhaupt PM; Cassera MB; Fröhlich RF; Hazleton KZ; Hefter JJ; Schramm VL; Akabas MH
    Mol Biochem Parasitol; 2010 Jan; 169(1):40-9. PubMed ID: 19818813
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Accessibility of substituted cysteines in TM2 and TM10 transmembrane segments in the
    Nishtala SN; Arora A; Reyes J; Akabas MH
    J Biol Chem; 2019 Feb; 294(6):1924-1935. PubMed ID: 30541922
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate and Inhibitor Specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1.
    Arora A; Deniskin R; Sosa Y; Nishtala SN; Henrich PP; Kumar TR; Fidock DA; Akabas MH
    Mol Pharmacol; 2016 Jun; 89(6):678-85. PubMed ID: 27048953
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Putative purine nucleoside interacting residues in the malaria parasite purine uptake transporter PfENT1 are critical for transporter function.
    Dillague C; Akabas MH
    PLoS One; 2023; 18(12):e0293923. PubMed ID: 38113238
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transport of nucleosides across the Plasmodium falciparum parasite plasma membrane has characteristics of PfENT1.
    Downie MJ; Saliba KJ; Howitt SM; Bröer S; Kirk K
    Mol Microbiol; 2006 May; 60(3):738-48. PubMed ID: 16629674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
    Wang C; Yu L; Zhang J; Zhou Y; Sun B; Xiao Q; Zhang M; Liu H; Li J; Li J; Luo Y; Xu J; Lian Z; Lin J; Wang X; Zhang P; Guo L; Ren R; Deng D
    Nat Commun; 2023 Mar; 14(1):1727. PubMed ID: 36977719
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity.
    Frame IJ; Merino EF; Schramm VL; Cassera MB; Akabas MH
    Biochem J; 2012 Sep; 446(2):179-90. PubMed ID: 22670848
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy.
    Parker MD; Hyde RJ; Yao SY; McRobert L; Cass CE; Young JD; McConkey GA; Baldwin SA
    Biochem J; 2000 Jul; 349(Pt 1):67-75. PubMed ID: 10861212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human equilibrative nucleoside transporter and the human facilitative nucleobase transporter.
    Quashie NB; Ranford-Cartwright LC; de Koning HP
    Malar J; 2010 Jan; 9():36. PubMed ID: 20113503
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heterologous Expression of a Novel Drug Transporter from the Malaria Parasite Alters Resistance to Quinoline Antimalarials.
    Tindall SM; Vallières C; Lakhani DH; Islahudin F; Ting KN; Avery SV
    Sci Rep; 2018 Feb; 8(1):2464. PubMed ID: 29410428
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Purine nucleobase transport in the intraerythrocytic malaria parasite.
    Downie MJ; Saliba KJ; Bröer S; Howitt SM; Kirk K
    Int J Parasitol; 2008 Feb; 38(2):203-9. PubMed ID: 17765902
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).
    Riegelhaupt PM; Frame IJ; Akabas MH
    J Biol Chem; 2010 May; 285(22):17001-10. PubMed ID: 20335165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nucleoside transport as a potential target for chemotherapy in malaria.
    Baldwin SA; McConkey GA; Cass CE; Young JD
    Curr Pharm Des; 2007; 13(6):569-80. PubMed ID: 17346175
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prevalence of mutations in Plasmodium falciparum genes associated with resistance to different antimalarial drugs in Nyando, Kisumu County in Kenya.
    Musyoka KB; Kiiru JN; Aluvaala E; Omondi P; Chege WK; Judah T; Kiboi D; Nganga JK; Kimani FT
    Infect Genet Evol; 2020 Mar; 78():104121. PubMed ID: 31756512
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of a novel putative inhibitor of the Plasmodium falciparum purine nucleoside phosphorylase: exploring the purine salvage pathway to design new antimalarial drugs.
    Kagami LP; das Neves GM; Rodrigues RP; da Silva VB; Eifler-Lima VL; Kawano DF
    Mol Divers; 2017 Aug; 21(3):677-695. PubMed ID: 28523625
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.