These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 31877895)

  • 1. Screening and Identification of Novel cGAS Homologues Using a Combination of in Vitro and In Vivo Protein Synthesis.
    Rolf J; Siedentop R; Lütz S; Rosenthal K
    Int J Mol Sci; 2019 Dec; 21(1):. PubMed ID: 31877895
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
    Hall J; Ralph EC; Shanker S; Wang H; Byrnes LJ; Horst R; Wong J; Brault A; Dumlao D; Smith JF; Dakin LA; Schmitt DC; Trujillo J; Vincent F; Griffor M; Aulabaugh AE
    Protein Sci; 2017 Dec; 26(12):2367-2380. PubMed ID: 28940468
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalytic Promiscuity of cGAS: A Facile Enzymatic Synthesis of 2'-3'-Linked Cyclic Dinucleotides.
    Rosenthal K; Becker M; Rolf J; Siedentop R; Hillen M; Nett M; Lütz S
    Chembiochem; 2020 Nov; 21(22):3225-3228. PubMed ID: 32633874
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
    Li X; Shu C; Yi G; Chaton CT; Shelton CL; Diao J; Zuo X; Kao CC; Herr AB; Li P
    Immunity; 2013 Dec; 39(6):1019-31. PubMed ID: 24332030
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A pyrophosphatase-coupled assay to monitor the NTase activity of cGAS.
    Hooy R; Sohn J
    Methods Enzymol; 2019; 625():77-86. PubMed ID: 31455538
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance.
    Zhou W; Whiteley AT; de Oliveira Mann CC; Morehouse BR; Nowak RP; Fischer ES; Gray NS; Mekalanos JJ; Kranzusch PJ
    Cell; 2018 Jul; 174(2):300-311.e11. PubMed ID: 30007416
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of novel highly sensitive methods to detect endogenous cGAMP in cells and tissue.
    Miyakawa S; Okui T; Shiraishi T; Yoshihara T; Hirayama M; Satomi Y; Hamada T; Nishida M; Akimoto C; Sato S
    J Immunol Methods; 2020 May; 480():112751. PubMed ID: 31982420
    [TBL] [Abstract][Full Text] [Related]  

  • 8. cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
    Slavik KM; Morehouse BR; Ragucci AE; Zhou W; Ai X; Chen Y; Li L; Wei Z; Bähre H; König M; Seifert R; Lee ASY; Cai H; Imler JL; Kranzusch PJ
    Nature; 2021 Sep; 597(7874):109-113. PubMed ID: 34261127
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer.
    Li T; Chen ZJ
    J Exp Med; 2018 May; 215(5):1287-1299. PubMed ID: 29622565
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Assessing the cGAS-cGAMP-STING Activity of Cancer Cells.
    Pépin G; Gantier MP
    Methods Mol Biol; 2018; 1725():257-266. PubMed ID: 29322423
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mn
    Zhao Z; Ma Z; Wang B; Guan Y; Su XD; Jiang Z
    Cell Rep; 2020 Aug; 32(7):108053. PubMed ID: 32814054
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The N terminus of cGAS de-oligomerizes the cGAS:DNA complex and lifts the DNA size restriction of core-cGAS activity.
    Lee A; Park EB; Lee J; Choi BS; Kang SJ
    FEBS Lett; 2017 Mar; 591(6):954-961. PubMed ID: 28214358
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.
    Almine JF; O'Hare CA; Dunphy G; Haga IR; Naik RJ; Atrih A; Connolly DJ; Taylor J; Kelsall IR; Bowie AG; Beard PM; Unterholzner L
    Nat Commun; 2017 Feb; 8():14392. PubMed ID: 28194029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. cGAS-STING Activation in the Tumor Microenvironment and Its Role in Cancer Immunity.
    Pépin G; Gantier MP
    Adv Exp Med Biol; 2017; 1024():175-194. PubMed ID: 28921470
    [TBL] [Abstract][Full Text] [Related]  

  • 15. cGAS is essential for the antitumor effect of immune checkpoint blockade.
    Wang H; Hu S; Chen X; Shi H; Chen C; Sun L; Chen ZJ
    Proc Natl Acad Sci U S A; 2017 Feb; 114(7):1637-1642. PubMed ID: 28137885
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response.
    Marcus A; Mao AJ; Lensink-Vasan M; Wang L; Vance RE; Raulet DH
    Immunity; 2018 Oct; 49(4):754-763.e4. PubMed ID: 30332631
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
    Gao D; Li T; Li XD; Chen X; Li QZ; Wight-Carter M; Chen ZJ
    Proc Natl Acad Sci U S A; 2015 Oct; 112(42):E5699-705. PubMed ID: 26371324
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of human cGAS activity and structure.
    Zhou W; Whiteley AT; Kranzusch PJ
    Methods Enzymol; 2019; 625():13-40. PubMed ID: 31455523
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
    Lama L; Adura C; Xie W; Tomita D; Kamei T; Kuryavyi V; Gogakos T; Steinberg JI; Miller M; Ramos-Espiritu L; Asano Y; Hashizume S; Aida J; Imaeda T; Okamoto R; Jennings AJ; Michino M; Kuroita T; Stamford A; Gao P; Meinke P; Glickman JF; Patel DJ; Tuschl T
    Nat Commun; 2019 May; 10(1):2261. PubMed ID: 31113940
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of hepatitis B virus replication by activation of the cGAS-STING pathway.
    He J; Hao R; Liu D; Liu X; Wu S; Guo S; Wang Y; Tien P; Guo D
    J Gen Virol; 2016 Dec; 97(12):3368-3378. PubMed ID: 27902332
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.