BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 31887298)

  • 1. Neutrophil elastase-mediated proteolysis of the tumor suppressor p200 CUX1 promotes cell proliferation and inhibits cell differentiation in APL.
    Yu L; Zhong L; Xiong L; Dan W; Li J; Ye J; Wan P; Luo X; Chu X; Liu C; He C; Mu F; Liu B
    Life Sci; 2020 Feb; 242():117229. PubMed ID: 31887298
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neutrophil elastase is important for PML-retinoic acid receptor alpha activities in early myeloid cells.
    Lane AA; Ley TJ
    Mol Cell Biol; 2005 Jan; 25(1):23-33. PubMed ID: 15601827
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neutrophil elastase and its therapeutic effect on leukemia cells.
    Jiang KL; Ma PP; Yang XQ; Zhong L; Wang H; Zhu XY; Liu BZ
    Mol Med Rep; 2015 Sep; 12(3):4165-4172. PubMed ID: 26081156
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression.
    Li H; Yang F; Hu A; Wang X; Fang E; Chen Y; Li D; Song H; Wang J; Guo Y; Liu Y; Li H; Huang K; Zheng L; Tong Q
    EMBO Mol Med; 2019 Dec; 11(12):e10835. PubMed ID: 31709724
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteolytic processing of cut homeobox 1 by neutrophil elastase in the MV4;11 myeloid leukemia cell line.
    Goulet B; Markovic Y; Leduy L; Nepveu A
    Mol Cancer Res; 2008 Apr; 6(4):644-53. PubMed ID: 18403643
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice.
    Lane AA; Ley TJ
    Cell; 2003 Oct; 115(3):305-18. PubMed ID: 14636558
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PML/RARα-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia.
    Bräuer-Hartmann D; Hartmann JU; Wurm AA; Gerloff D; Katzerke C; Verga Falzacappa MV; Pelicci PG; Müller-Tidow C; Tenen DG; Niederwieser D; Behre G
    Cancer Res; 2015 Aug; 75(16):3411-24. PubMed ID: 26041820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Over-expression of neutrophil elastase promotes proliferation and inhibits apoptosis in K562 cells].
    Jiang K; Ma P; Yang X; Zhong L; Wang H; Zhu X; Liu B
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2015 Feb; 31(2):159-62, 167. PubMed ID: 25652853
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.
    Ng AP; Nin DS; Fong JH; Venkataraman D; Chen CS; Khan M
    Mol Cancer Ther; 2007 Aug; 6(8):2240-8. PubMed ID: 17699721
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PML-RAR alpha induces the downmodulation of HHEX: a key event responsible for the induction of an angiogenetic response.
    Saulle E; Petronelli A; Pelosi E; Coppotelli E; Pasquini L; Ilari R; Lo-Coco F; Testa U
    J Hematol Oncol; 2016 Apr; 9():33. PubMed ID: 27052408
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemia.
    Uy GL; Lane AA; Welch JS; Grieselhuber NR; Payton JE; Ley TJ
    Blood; 2010 Nov; 116(18):3604-10. PubMed ID: 20647568
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential gene expression in retinoic acid-induced differentiation of acute promyelocytic leukemia cells, NB4 and HL-60 cells.
    Lee KH; Chang MY; Ahn JI; Yu DH; Jung SS; Choi JH; Noh YH; Lee YS; Ahn MJ
    Biochem Biophys Res Commun; 2002 Sep; 296(5):1125-33. PubMed ID: 12207890
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C/EBPα and PU.1 are involved in distinct differentiation responses of acute promyelocytic leukemia HL-60 and NB4 cells via chromatin remodeling.
    Savickiene J; Treigyte G; Vistartaite G; Tunaitis V; Magnusson KE; Navakauskiene R
    Differentiation; 2011 Jan; 81(1):57-67. PubMed ID: 20864248
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
    McNerney ME; Brown CD; Wang X; Bartom ET; Karmakar S; Bandlamudi C; Yu S; Ko J; Sandall BP; Stricker T; Anastasi J; Grossman RL; Cunningham JM; Le Beau MM; White KP
    Blood; 2013 Feb; 121(6):975-83. PubMed ID: 23212519
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling.
    Yang R; Zhong L; Yang XQ; Jiang KL; Li L; Song H; Liu BZ
    Mol Med Rep; 2016 May; 13(5):4175-82. PubMed ID: 27035679
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence.
    Li K; Wang F; Cao WB; Lv XX; Hua F; Cui B; Yu JJ; Zhang XW; Shang S; Liu SS; Yu JM; Han MZ; Huang B; Zhang TT; Li X; Jiang JD; Hu ZW
    Cancer Cell; 2017 May; 31(5):697-710.e7. PubMed ID: 28486108
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CUX1: a modulator of tumour aggressiveness in pancreatic neuroendocrine neoplasms.
    Krug S; Kühnemuth B; Griesmann H; Neesse A; Mühlberg L; Boch M; Kortenhaus J; Fendrich V; Wiese D; Sipos B; Friemel J; Gress TM; Michl P
    Endocr Relat Cancer; 2014; 21(6):879-90. PubMed ID: 25248790
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia.
    Wang X; Tan Y; Li Y; Li J; Jin W; Wang K
    Front Med; 2016 Dec; 10(4):420-429. PubMed ID: 27888400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth suppression of acute promyelocytic leukemia cells having increased expression of the non-rearranged alleles: RAR alpha or PML.
    Ahn MJ; Nason-Burchenal K; Moasser MM; Dmitrovsky E
    Oncogene; 1995 Jun; 10(12):2307-14. PubMed ID: 7784078
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FOXO3A as a key molecule for all-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia.
    Sakoe Y; Sakoe K; Kirito K; Ozawa K; Komatsu N
    Blood; 2010 May; 115(18):3787-95. PubMed ID: 20215638
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.