581 related articles for article (PubMed ID: 31888761)
1. Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer.
Yang L; Lei Q; Li L; Yang J; Dong Z; Cui H
Clin Epigenetics; 2019 Dec; 11(1):199. PubMed ID: 31888761
[TBL] [Abstract][Full Text] [Related]
2. Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer.
Zhang X; Liu D; Li M; Cao C; Wan D; Xi B; Li W; Tan J; Wang J; Wu Z; Ma D; Gao Q
J Hematol Oncol; 2017 Jan; 10(1):29. PubMed ID: 28114995
[TBL] [Abstract][Full Text] [Related]
3. Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
Zhou Z; Chen H; Xie R; Wang H; Li S; Xu Q; Xu N; Cheng Q; Qian Y; Huang R; Shao Z; Xiang M
Mol Oncol; 2019 Apr; 13(4):873-893. PubMed ID: 30628173
[TBL] [Abstract][Full Text] [Related]
4. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
Rau RE; Rodriguez BA; Luo M; Jeong M; Rosen A; Rogers JH; Campbell CT; Daigle SR; Deng L; Song Y; Sweet S; Chevassut T; Andreeff M; Kornblau SM; Li W; Goodell MA
Blood; 2016 Aug; 128(7):971-81. PubMed ID: 27335278
[TBL] [Abstract][Full Text] [Related]
5. The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription.
Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D; Liu PY; Zhang XD; Hüttelmaier S; Wong JWH; Wang J; Polly P; Perini G; Scarlett CJ; Liu T
Cancer Res; 2017 May; 77(9):2522-2533. PubMed ID: 28209620
[TBL] [Abstract][Full Text] [Related]
6. Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.
Vatapalli R; Sagar V; Rodriguez Y; Zhao JC; Unno K; Pamarthy S; Lysy B; Anker J; Han H; Yoo YA; Truica M; Chalmers ZR; Giles F; Yu J; Chakravarti D; Carneiro B; Abdulkadir SA
Nat Commun; 2020 Aug; 11(1):4153. PubMed ID: 32814769
[TBL] [Abstract][Full Text] [Related]
7. The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.
Wang WT; Chen TQ; Zeng ZC; Pan Q; Huang W; Han C; Fang K; Sun LY; Yang QQ; Wang D; Luo XQ; Sun YM; Chen YQ
J Hematol Oncol; 2020 Jun; 13(1):78. PubMed ID: 32552847
[TBL] [Abstract][Full Text] [Related]
8. Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.
Peng K; Kou L; Yu L; Bai C; Li M; Mo P; Li W; Yu C
Gastroenterology; 2019 Mar; 156(4):1112-1126. PubMed ID: 30472235
[TBL] [Abstract][Full Text] [Related]
9. miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L.
Lv L; Li Q; Chen S; Zhang X; Tao X; Tang X; Wang S; Che G; Yu Y; He L
Exp Cell Res; 2019 Dec; 385(1):111597. PubMed ID: 31525340
[TBL] [Abstract][Full Text] [Related]
10. The role of DOT1L in the proliferation and prognosis of gastric cancer.
Song Z; Wei Z; Wang Q; Zhang X; Tao X; Wu N; Liu X; Qian J
Biosci Rep; 2020 Jan; 40(1):. PubMed ID: 31939604
[TBL] [Abstract][Full Text] [Related]
11. SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression.
Cao N; Yu Y; Zhu H; Chen M; Chen P; Zhuo M; Mao Y; Li L; Zhao Q; Wu M; Ye M
Cell Death Dis; 2020 May; 11(5):351. PubMed ID: 32393761
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.
Zhang L; Deng L; Chen F; Yao Y; Wu B; Wei L; Mo Q; Song Y
Oncotarget; 2014 Nov; 5(21):10665-77. PubMed ID: 25359765
[TBL] [Abstract][Full Text] [Related]
13. Antiproliferative and Antimigration Activities of Fluoro-Neplanocin A via Inhibition of Histone H3 Methylation in Triple-Negative Breast Cancer.
Byun WS; Kim WK; Yoon JS; Jarhad DB; Jeong LS; Lee SK
Biomolecules; 2020 Mar; 10(4):. PubMed ID: 32244385
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of Disruptor of Telomeric Silencing 1-Like Alleviated Renal Ischemia and Reperfusion Injury-Induced Fibrosis by Blocking PI3K/AKT-Mediated Oxidative Stress.
Yang C; Chen Z; Yu H; Liu X
Drug Des Devel Ther; 2019; 13():4375-4387. PubMed ID: 31920287
[TBL] [Abstract][Full Text] [Related]
15. DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A.
Leon KE; Buj R; Lesko E; Dahl ES; Chen CW; Tangudu NK; Imamura-Kawasawa Y; Kossenkov AV; Hobbs RP; Aird KM
J Cell Biol; 2021 Aug; 220(8):. PubMed ID: 34037658
[TBL] [Abstract][Full Text] [Related]
16. Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation.
Kim W; Kim R; Park G; Park JW; Kim JE
J Biol Chem; 2012 Feb; 287(8):5588-99. PubMed ID: 22190683
[TBL] [Abstract][Full Text] [Related]
17. Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages.
Chen X; Liu X; Zhang Y; Huai W; Zhou Q; Xu S; Chen X; Li N; Cao X
Cell Mol Immunol; 2020 Jan; 17(1):76-84. PubMed ID: 30275539
[TBL] [Abstract][Full Text] [Related]
18. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
Steger DJ; Lefterova MI; Ying L; Stonestrom AJ; Schupp M; Zhuo D; Vakoc AL; Kim JE; Chen J; Lazar MA; Blobel GA; Vakoc CR
Mol Cell Biol; 2008 Apr; 28(8):2825-39. PubMed ID: 18285465
[TBL] [Abstract][Full Text] [Related]
19. DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation.
Cao K; Ugarenko M; Ozark PA; Wang J; Marshall SA; Rendleman EJ; Liang K; Wang L; Zou L; Smith ER; Yue F; Shilatifard A
Proc Natl Acad Sci U S A; 2020 Nov; 117(44):27365-27373. PubMed ID: 33077595
[TBL] [Abstract][Full Text] [Related]
20. DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling.
Ishiguro K; Kitajima H; Niinuma T; Ishida T; Maruyama R; Ikeda H; Hayashi T; Sasaki H; Wakasugi H; Nishiyama K; Shindo T; Yamamoto E; Kai M; Sasaki Y; Tokino T; Nakase H; Suzuki H
Haematologica; 2019 Jan; 104(1):155-165. PubMed ID: 30171029
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
