290 related articles for article (PubMed ID: 31892271)
1. Design, Synthesis and Molecular Modeling Study of Conjugates of ADP and Morpholino Nucleosides as A Novel Class of Inhibitors of PARP-1, PARP-2 and PARP-3.
Sherstyuk YV; Ivanisenko NV; Zakharenko AL; Sukhanova MV; Peshkov RY; Eltsov IV; Kutuzov MM; Kurgina TA; Belousova EA; Ivanisenko VA; Lavrik OI; Silnikov VN; Abramova TV
Int J Mol Sci; 2019 Dec; 21(1):. PubMed ID: 31892271
[TBL] [Abstract][Full Text] [Related]
2. Poly(ADP-ribose) Polymerase (PARP) and PARP Inhibitors: Mechanisms of Action and Role in Cardiovascular Disorders.
Henning RJ; Bourgeois M; Harbison RD
Cardiovasc Toxicol; 2018 Dec; 18(6):493-506. PubMed ID: 29968072
[TBL] [Abstract][Full Text] [Related]
3. Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation.
Gibson BA; Zhang Y; Jiang H; Hussey KM; Shrimp JH; Lin H; Schwede F; Yu Y; Kraus WL
Science; 2016 Jul; 353(6294):45-50. PubMed ID: 27256882
[TBL] [Abstract][Full Text] [Related]
4. Using Clickable NAD
Zhang L; Lin H
Methods Mol Biol; 2017; 1608():95-109. PubMed ID: 28695506
[TBL] [Abstract][Full Text] [Related]
5. Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy.
Kuchmerovska T; Shymanskyy I; Donchenko G; Kuchmerovskyy M; Pakirbaieva L; Klimenko A
J Diabetes Complications; 2004; 18(4):198-204. PubMed ID: 15207836
[TBL] [Abstract][Full Text] [Related]
6. Identifying Direct Protein Targets of Poly-ADP-Ribose Polymerases (PARPs) Using Engineered PARP Variants-Orthogonal Nicotinamide Adenine Dinucleotide (NAD+) Analog Pairs.
Carter-O'Connell I; Cohen MS
Curr Protoc Chem Biol; 2015 Jun; 7(2):121-39. PubMed ID: 26344237
[TBL] [Abstract][Full Text] [Related]
7. A versatile strategy for the design and synthesis of novel ADP conjugates and their evaluation as potential poly(ADP-ribose) polymerase 1 inhibitors.
Sherstyuk YV; Zakharenko AL; Kutuzov MM; Chalova PV; Sukhanova MV; Lavrik OI; Silnikov VN; Abramova TV
Mol Divers; 2017 Feb; 21(1):101-113. PubMed ID: 27677737
[TBL] [Abstract][Full Text] [Related]
8. NAD+ analogs substituted in the purine base as substrates for poly(ADP-ribosyl) transferase.
Oei SL; Griesenbeck J; Buchlow G; Jorcke D; Mayer-Kuckuk P; Wons T; Ziegler M
FEBS Lett; 1996 Nov; 397(1):17-21. PubMed ID: 8941705
[TBL] [Abstract][Full Text] [Related]
9. Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres.
Ekblad T; Schüler H
Chem Biol Drug Des; 2016 Mar; 87(3):478-82. PubMed ID: 26518726
[TBL] [Abstract][Full Text] [Related]
10. Chain length analysis of ADP-ribose polymers generated by poly(ADP-ribose) polymerase (PARP) as a function of beta-NAD+ and enzyme concentrations.
Mendoza-Alvarez H; Chavez-Bueno S; Alvarez-Gonzalez R
IUBMB Life; 2000 Aug; 50(2):145-9. PubMed ID: 11185961
[TBL] [Abstract][Full Text] [Related]
11. In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement.
Wigle TJ; Blackwell DJ; Schenkel LB; Ren Y; Church WD; Desai HJ; Swinger KK; Santospago AG; Majer CR; Lu AZ; Niepel M; Perl NR; Vasbinder MM; Keilhack H; Kuntz KW
Cell Chem Biol; 2020 Jul; 27(7):877-887.e14. PubMed ID: 32679093
[TBL] [Abstract][Full Text] [Related]
12. Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells.
Okuda A; Kurokawa S; Takehashi M; Maeda A; Fukuda K; Kubo Y; Nogusa H; Takatani-Nakase T; Okuda S; Ueda K; Tanaka S
BMC Neurosci; 2017 Jan; 18(1):14. PubMed ID: 28095779
[TBL] [Abstract][Full Text] [Related]
13. Structure and function of poly(ADP-ribose) polymerase-1: role in oxidative stress-related pathologies.
Virág L
Curr Vasc Pharmacol; 2005 Jul; 3(3):209-14. PubMed ID: 16026317
[TBL] [Abstract][Full Text] [Related]
14. Poly(ADP-ribose)--a unique natural polymer structural features, biological role and approaches to the chemical synthesis.
Drenichev MS; Mikhailov SN
Nucleosides Nucleotides Nucleic Acids; 2015; 34(4):258-76. PubMed ID: 25774719
[TBL] [Abstract][Full Text] [Related]
15. Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked?
Zhang J
Bioessays; 2003 Aug; 25(8):808-14. PubMed ID: 12879452
[TBL] [Abstract][Full Text] [Related]
16. Binding mode of novel 1-substituted quinazoline derivatives to poly(ADP-ribose) polymerase-catalytic domain, revealed by X-ray crystal structure analysis of complexes.
Matsumoto K; Kondo K; Ota T; Kawashima A; Kitamura K; Ishida T
Biochim Biophys Acta; 2006 May; 1764(5):913-9. PubMed ID: 16631419
[TBL] [Abstract][Full Text] [Related]
17. Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.
Mangerich A; Debiak M; Birtel M; Ponath V; Balszuweit F; Lex K; Martello R; Burckhardt-Boer W; Strobelt R; Siegert M; Thiermann H; Steinritz D; Schmidt A; Bürkle A
Toxicol Lett; 2016 Feb; 244():56-71. PubMed ID: 26383629
[TBL] [Abstract][Full Text] [Related]
18. Progress in the function and regulation of ADP-Ribosylation.
Hottiger MO; Boothby M; Koch-Nolte F; Lüscher B; Martin NM; Plummer R; Wang ZQ; Ziegler M
Sci Signal; 2011 May; 4(174):mr5. PubMed ID: 21610250
[TBL] [Abstract][Full Text] [Related]
19. Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by the synthetic "C" nucleoside analogs, tiazofurin and selenazofurin. A new strategy for cancer chemotherapy.
Berger NA; Berger SJ; Catino DM; Petzold SJ; Robins RK
J Clin Invest; 1985 Feb; 75(2):702-9. PubMed ID: 3919063
[TBL] [Abstract][Full Text] [Related]
20. Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations.
Geraets L; Moonen HJ; Wouters EF; Bast A; Hageman GJ
Biochem Pharmacol; 2006 Sep; 72(7):902-10. PubMed ID: 16870158
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]