145 related articles for article (PubMed ID: 31898998)
1. Design and biological evaluation of tetrahydropyridine derivatives as novel human GPR119 agonists.
Zuo Z; Chen M; Shao X; Qian X; Liu X; Zhou X; Xiang J; Deng P; Li Y; Jie H; Liu C; Cen X; Xie Y; Zhao Y
Bioorg Med Chem Lett; 2020 Feb; 30(4):126855. PubMed ID: 31898998
[TBL] [Abstract][Full Text] [Related]
2. Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators.
Fang Y; Zhang S; Wu W; Liu Y; Yang J; Li Y; Li M; Dong H; Jin Y; Liu R; Yang Z
Bioorg Chem; 2020 Jan; 94():103390. PubMed ID: 31662212
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of 2-(4-(methylsulfonyl)phenyl)pyridine derivatives as GPR119 agonists.
Zhou Y; Zhu X; Zhang L; Tang C; Feng B
Chem Biol Drug Des; 2019 Jan; 93(1):67-74. PubMed ID: 30120879
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and biological evaluation of novel 7-azaspiro[3.5]nonane derivatives as GPR119 agonists.
Matsuda D; Kawamura M; Kobashi Y; Shiozawa F; Suga Y; Fusegi K; Nishimoto S; Kimura K; Miyoshi M; Takayama N; Kakinuma H; Ohtake N
Bioorg Med Chem; 2018 May; 26(8):1832-1847. PubMed ID: 29486951
[TBL] [Abstract][Full Text] [Related]
5. Novel GPR119 agonist HD0471042 attenuated type 2 diabetes mellitus.
Ha TY; Kim YS; Kim CH; Choi HS; Yang J; Park SH; Kim DH; Rhee JK
Arch Pharm Res; 2014 May; 37(5):671-8. PubMed ID: 23897163
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of 1, 2, 4-oxadiazole derivatives as novel GPR119 agonists.
Fu S; Xiang W; Chen J; Ma L; Chen L
Chem Biol Drug Des; 2017 May; 89(5):815-819. PubMed ID: 27779815
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series.
Han S; Narayanan S; Kim SH; Calderon I; Zhu X; Kawasaki A; Yue D; Lehmann J; Wong A; Buzard DJ; Semple G; Carroll C; Chu ZL; Al-Sharmma H; Shu HH; Tung SF; Unett DJ; Behan DP; Yoon WH; Morgan M; Usmani KA; Chen C; Sadeque A; Leonard JN; Jones RM
Bioorg Med Chem Lett; 2015 Aug; 25(15):3034-8. PubMed ID: 26048791
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure.
Harada K; Mizukami J; Kadowaki S; Matsuda I; Watanabe T; Oe Y; Kodama Y; Aoki K; Suwa K; Fukuda S; Yata S; Inaba T
Bioorg Med Chem Lett; 2018 Apr; 28(7):1228-1233. PubMed ID: 29519733
[TBL] [Abstract][Full Text] [Related]
9. Optimization of a novel series of potent and orally bioavailable GPR119 agonists.
Koshizawa T; Morimoto T; Watanabe G; Watanabe T; Yamasaki N; Sawada Y; Fukuda T; Okuda A; Shibuya K; Ohgiya T
Bioorg Med Chem Lett; 2017 Aug; 27(15):3249-3253. PubMed ID: 28648463
[TBL] [Abstract][Full Text] [Related]
10. Discovery and biological evaluation of novel G protein-coupled receptor 119 agonists for type 2 diabetes.
Zhou Y; Wang Y; Zhang L; Tang C; Feng B
Arch Pharm (Weinheim); 2019 Apr; 352(4):e1800267. PubMed ID: 30740769
[TBL] [Abstract][Full Text] [Related]
11. Discovery, optimisation and in vivo evaluation of novel GPR119 agonists.
Brocklehurst KJ; Broo A; Butlin RJ; Brown HS; Clarke DS; Davidsson Ö; Goldberg K; Groombridge SD; Kelly EE; Leach A; McKerrecher D; O'Donnell C; Poucher S; Schofield P; Scott JS; Teague J; Westgate L; Wood MJ
Bioorg Med Chem Lett; 2011 Dec; 21(24):7310-6. PubMed ID: 22061639
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and SAR studies of bicyclic amine series GPR119 agonists.
Sakairi M; Kogami M; Torii M; Kataoka H; Fujieda H; Makino M; Kataoka D; Okamoto R; Miyazawa T; Okabe M; Inoue M; Takahashi N; Harada S; Watanabe N
Bioorg Med Chem Lett; 2012 Aug; 22(15):5123-8. PubMed ID: 22765901
[TBL] [Abstract][Full Text] [Related]
13. The optimization of xanthine derivatives leading to HBK001 hydrochloride as a potent dual ligand targeting DPP-IV and GPR119.
Li G; Meng B; Yuan B; Huan Y; Zhou T; Jiang Q; Lei L; Sheng L; Wang W; Gong N; Lu Y; Ma C; Li Y; Shen Z; Huang H
Eur J Med Chem; 2020 Feb; 188():112017. PubMed ID: 31926470
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.
Fang Y; Xu J; Li Z; Yang Z; Xiong L; Jin Y; Wang Q; Xie S; Zhu W; Chang S
Bioorg Med Chem; 2018 Aug; 26(14):4080-4087. PubMed ID: 30100020
[TBL] [Abstract][Full Text] [Related]
15. Discovery of novel xanthine compounds targeting DPP-IV and GPR119 as anti-diabetic agents.
Li G; Huan Y; Yuan B; Wang J; Jiang Q; Lin Z; Shen Z; Huang H
Eur J Med Chem; 2016 Nov; 124():103-116. PubMed ID: 27560285
[TBL] [Abstract][Full Text] [Related]
16. Optimisation of novel 4, 8-disubstituted dihydropyrimido[5,4-
Fang Y; Zhang S; Li M; Xiong L; Tu L; Xie S; Jin Y; Liu Y; Yang Z; Liu R
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):50-58. PubMed ID: 31656107
[TBL] [Abstract][Full Text] [Related]
17. Discovery of structurally novel, potent and orally efficacious GPR119 agonists.
Alper P; Azimioara M; Cow C; Mutnick D; Nikulin V; Michellys PY; Wang Z; Reding E; Paliotti M; Li J; Bao D; Zoll J; Kim Y; Zimmerman M; Groessel T; Tuntland T; Joseph SB; McNamara P; Seidel HM; Epple R
Bioorg Med Chem Lett; 2014 May; 24(10):2383-7. PubMed ID: 24751443
[TBL] [Abstract][Full Text] [Related]
18. Discovery of a novel series of GPR119 agonists: Design, synthesis, and biological evaluation of N-(Piperidin-4-yl)-N-(trifluoromethyl)pyrimidin-4-amine derivatives.
Kubo O; Takami K; Kamaura M; Watanabe K; Miyashita H; Abe S; Matsuda K; Tsujihata Y; Odani T; Iwasaki S; Kitazaki T; Murata T; Sato K
Bioorg Med Chem; 2021 Jul; 41():116208. PubMed ID: 34010766
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist.
Yang Z; Fang Y; Park H
Bioorg Med Chem Lett; 2017 Jun; 27(11):2515-2519. PubMed ID: 28408218
[TBL] [Abstract][Full Text] [Related]
20. GPR119 agonists: Novel therapeutic agents for type 2 diabetes mellitus.
Manaithiya A; Alam O; Sharma V; Javed Naim M; Mittal S; Khan IA
Bioorg Chem; 2021 Aug; 113():104998. PubMed ID: 34048996
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
