BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 31906838)

  • 1. Use of Small-molecule Inhibitory Compound of PERK-dependent Signaling Pathway as a Promising Target-based Therapy for Colorectal Cancer.
    Rozpędek W; Pytel D; Wawrzynkiewicz A; Siwecka N; Dziki A; Dziki Ł; Diehl JA; Majsterek I
    Curr Cancer Drug Targets; 2020; 20(3):223-238. PubMed ID: 31906838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the PERK-Dependent Unfolded Protein Response Signaling Pathway Involved in the Pathogenesis of Alzheimer's Disease.
    Rozpędek W; Pytel D; Popławski T; Walczak A; Gradzik K; Wawrzynkiewicz A; Wojtczak R; Mucha B; Diehl JA; Majsterek I
    Curr Alzheimer Res; 2019; 16(3):209-218. PubMed ID: 30819079
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small-molecule inhibitors of the PERK-mediated Unfolded Protein Response signaling pathway in targeted therapy for colorectal cancer.
    Rozpedek-Kaminska W; Piotrzkowska D; Galita G; Pytel D; Kucharska E; Dziki Ł; Dziki A; Majsterek I
    Pol Przegl Chir; 2022 Mar; 94(6):17-25. PubMed ID: 36468513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of PERK-dependent pro-adaptive signaling pathway as a promising approach for cancer treatment.
    Rozpędek W; Pytel D; Dziki Ł; Nowak A; Dziki A; Diehl JA; Majsterek I
    Pol Przegl Chir; 2017 Jun; 89(3):7-10. PubMed ID: 28703114
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment.
    Rozpędek-Kamińska W; Galita G; Siwecka N; Carroll SL; Diehl JA; Kucharska E; Pytel D; Majsterek I
    Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33925820
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PERK activation by CCT020312 chemosensitizes colorectal cancer through inducing apoptosis regulated by ER stress.
    Lei Y; He L; Yan C; Wang Y; Lv G
    Biochem Biophys Res Commun; 2021 Jun; 557():316-322. PubMed ID: 33894420
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells.
    Chou LC; Yang JS; Huang LJ; Wu HC; Lu CC; Chiang JH; Chen KT; Kuo SC; Chung JG
    J Gastroenterol; 2009; 44(10):1055-63. PubMed ID: 19688288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis.
    Moon HS; Kim B; Gwak H; Suh DH; Song YS
    Mol Carcinog; 2016 Apr; 55(4):346-56. PubMed ID: 25663310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence for eIF2α phosphorylation-independent effects of GSK2656157, a novel catalytic inhibitor of PERK with clinical implications.
    Krishnamoorthy J; Rajesh K; Mirzajani F; Kesoglidou P; Papadakis AI; Koromilas AE
    Cell Cycle; 2014; 13(5):801-6. PubMed ID: 24401334
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.
    Trisciuoglio D; Uranchimeg B; Cardellina JH; Meragelman TL; Matsunaga S; Fusetani N; Del Bufalo D; Shoemaker RH; Melillo G
    J Natl Cancer Inst; 2008 Sep; 100(17):1233-46. PubMed ID: 18728285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein kinase RNA-like ER kinase/eukaryotic translation initiation factor 2α pathway attenuates tumor necrosis factor alpha-induced apoptosis in nucleus pulposus cells by activating autophagy.
    Chen L; Liu L; Xie ZY; Wang F; Zhu L; Zhang C; Fan P; Sinkemani A; Hong X; Wu XT
    J Cell Physiol; 2019 Jul; 234(7):11631-11645. PubMed ID: 30515797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-Hydroxymethylfurfural protects against ER stress-induced apoptosis in GalN/TNF-α-injured L02 hepatocytes through regulating the PERK-eIF2α signaling pathway.
    Jiang ZQ; Ma YX; Li MH; Zhan XQ; Zhang X; Wang MY
    Chin J Nat Med; 2015 Dec; 13(12):896-905. PubMed ID: 26721708
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Niskocząsteczkowe inhibitory szlaku adaptacyjnej odpowiedzi na stres zależnego od kinazy PERK jako nowatorska strategia terapeutyczna w leczeniu choroby Alzheimera].
    Rozpędek W; Pytel D; Diehl JA; Majsterek I
    Pol Merkur Lekarski; 2019 Jan; 46(271):9-15. PubMed ID: 30810108
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway.
    Hamanaka RB; Bennett BS; Cullinan SB; Diehl JA
    Mol Biol Cell; 2005 Dec; 16(12):5493-501. PubMed ID: 16176978
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer's Disease.
    Rozpedek W; Markiewicz L; Diehl JA; Pytel D; Majsterek I
    Curr Med Chem; 2015; 22(27):3169-84. PubMed ID: 26282939
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pollen Typhae Total Flavone Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis in Human Aortic-Vascular Smooth Muscle Cells through Down-Regulating PERK-eIF2α-ATF4-CHOP Pathway.
    Chen MT; Huang RL; Ou LJ; Chen YN; Men L; Chang X; Wang L; Yang YZ; Zhang Z
    Chin J Integr Med; 2019 Aug; 25(8):604-612. PubMed ID: 30707413
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of PERK/eIF2α/CHOP Endoplasmic Reticulum Stress Pathway in Oxidized Low-density Lipoprotein Mediated Induction of Endothelial Apoptosis.
    Tao YK; Yu PL; Bai YP; Yan ST; Zhao SP; Zhang GQ
    Biomed Environ Sci; 2016 Dec; 29(12):868-876. PubMed ID: 28081747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum.
    Wu S; Hu Y; Wang JL; Chatterjee M; Shi Y; Kaufman RJ
    J Biol Chem; 2002 May; 277(20):18077-83. PubMed ID: 11877419
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress.
    Rozpedek W; Pytel D; Mucha B; Leszczynska H; Diehl JA; Majsterek I
    Curr Mol Med; 2016; 16(6):533-44. PubMed ID: 27211800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation.
    Xie W; Pariollaud M; Wixted WE; Chitnis N; Fornwald J; Truong M; Pao C; Liu Y; Ames RS; Callahan J; Solari R; Sanchez Y; Diehl A; Li H
    PLoS One; 2015; 10(3):e0119738. PubMed ID: 25780921
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.