BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 31908356)

  • 1. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function.
    Yoo H; Lee YJ; Park C; Son D; Choi DY; Park JH; Choi HJ; La HW; Choi YJ; Moon EH; Saur D; Chung HM; Song H; Do JT; Jang H; Lee DR; Park C; Lee OH; Cho SG; Hong SH; Kong G; Kim JH; Choi Y; Hong K
    Cell Death Dis; 2020 Jan; 11(1):14. PubMed ID: 31908356
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation.
    Cao K; Ugarenko M; Ozark PA; Wang J; Marshall SA; Rendleman EJ; Liang K; Wang L; Zou L; Smith ER; Yue F; Shilatifard A
    Proc Natl Acad Sci U S A; 2020 Nov; 117(44):27365-27373. PubMed ID: 33077595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia.
    Wang F; Ngo J; Li Y; Liu H; Chen CH; Saifudeen Z; Sequeira-Lopez MLS; El-Dahr SS
    Epigenetics; 2021 Nov; 16(11):1235-1250. PubMed ID: 33315499
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo.
    Bovio PP; Franz H; Heidrich S; Rauleac T; Kilpert F; Manke T; Vogel T
    Mol Neurobiol; 2019 Jun; 56(6):4273-4287. PubMed ID: 30302725
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages.
    Chen X; Liu X; Zhang Y; Huai W; Zhou Q; Xu S; Chen X; Li N; Cao X
    Cell Mol Immunol; 2020 Jan; 17(1):76-84. PubMed ID: 30275539
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
    Steger DJ; Lefterova MI; Ying L; Stonestrom AJ; Schupp M; Zhuo D; Vakoc AL; Kim JE; Chen J; Lazar MA; Blobel GA; Vakoc CR
    Mol Cell Biol; 2008 Apr; 28(8):2825-39. PubMed ID: 18285465
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer.
    Zhang X; Liu D; Li M; Cao C; Wan D; Xi B; Li W; Tan J; Wang J; Wu Z; Ma D; Gao Q
    J Hematol Oncol; 2017 Jan; 10(1):29. PubMed ID: 28114995
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.
    Ho LL; Sinha A; Verzi M; Bernt KM; Armstrong SA; Shivdasani RA
    Mol Cell Biol; 2013 May; 33(9):1735-45. PubMed ID: 23428873
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8
    Kwesi-Maliepaard EM; Aslam MA; Alemdehy MF; van den Brand T; McLean C; Vlaming H; van Welsem T; Korthout T; Lancini C; Hendriks S; Ahrends T; van Dinther D; den Haan JMM; Borst J; de Wit E; van Leeuwen F; Jacobs H
    Proc Natl Acad Sci U S A; 2020 Aug; 117(34):20706-20716. PubMed ID: 32764145
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.
    Lin H; Cossu IG; Leu NA; Deshpande AJ; Bernt KM; Luo M; Wang PJ
    Development; 2023 May; 150(9):. PubMed ID: 37082953
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Maternal DOT1L is dispensable for mouse development.
    Liao J; Szabó PE
    Sci Rep; 2020 Nov; 10(1):20636. PubMed ID: 33244015
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DOT1L Activity Promotes Proliferation and Protects Cortical Neural Stem Cells from Activation of ATF4-DDIT3-Mediated ER Stress In Vitro.
    Roidl D; Hellbach N; Bovio PP; Villarreal A; Heidrich S; Nestel S; Grüning BA; Boenisch U; Vogel T
    Stem Cells; 2016 Jan; 34(1):233-45. PubMed ID: 26299268
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone methyltransferase Dot1L plays a role in postembryonic development in Xenopus tropicalis.
    Wen L; Fu L; Guo X; Chen Y; Shi YB
    FASEB J; 2015 Feb; 29(2):385-93. PubMed ID: 25366346
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Folate deficiency reduced aberrant level of DOT1L-mediated histone H3K79 methylation causes disruptive SHH gene expression involved in neural tube defects.
    Li X; Pei P; Shen J; Yu J; Wang F; Wang L; Liu C; Wang S
    Epigenetics Chromatin; 2023 Dec; 16(1):50. PubMed ID: 38093377
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Common and distinct functions of mouse Dot1l in the regulation of endothelial transcriptome.
    Yoo H; La H; Park C; Yoo S; Lee H; Song H; Do JT; Choi Y; Hong K
    Front Cell Dev Biol; 2023; 11():1176115. PubMed ID: 37397258
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of fatty acid β-oxidation in lymphangiogenesis.
    Wong BW; Wang X; Zecchin A; Thienpont B; Cornelissen I; Kalucka J; García-Caballero M; Missiaen R; Huang H; Brüning U; Blacher S; Vinckier S; Goveia J; Knobloch M; Zhao H; Dierkes C; Shi C; Hägerling R; Moral-Dardé V; Wyns S; Lippens M; Jessberger S; Fendt SM; Luttun A; Noel A; Kiefer F; Ghesquière B; Moons L; Schoonjans L; Dewerchin M; Eelen G; Lambrechts D; Carmeliet P
    Nature; 2017 Feb; 542(7639):49-54. PubMed ID: 28024299
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of Transcriptional and Epigenetic Regulation in Lymphatic Endothelial Cell Development.
    La H; Yoo H; Park YB; Thang NX; Park C; Yoo S; Lee H; Choi Y; Song H; Do JT; Hong K
    Cells; 2022 May; 11(10):. PubMed ID: 35626729
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DOT1L-mediated murine neuronal differentiation associates with H3K79me2 accumulation and preserves SOX2-enhancer accessibility.
    Ferrari F; Arrigoni L; Franz H; Izzo A; Butenko L; Trompouki E; Vogel T; Manke T
    Nat Commun; 2020 Oct; 11(1):5200. PubMed ID: 33060580
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.
    Willemsen L; Prange KHM; Neele AE; van Roomen CPAA; Gijbels M; Griffith GR; Toom MD; Beckers L; Siebeler R; Spann NJ; Chen HJ; Bosmans LA; Gorbatenko A; van Wouw S; Zelcer N; Jacobs H; van Leeuwen F; de Winther MPJ
    Cell Rep; 2022 Nov; 41(8):111703. PubMed ID: 36417856
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells.
    Tacconi C; He Y; Ducoli L; Detmar M
    Angiogenesis; 2021 Feb; 24(1):67-82. PubMed ID: 32918672
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.