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3. PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect. Cristóbal I; Garcia-Orti L; Cirauqui C; Alonso MM; Calasanz MJ; Odero MD Leukemia; 2011 Apr; 25(4):606-14. PubMed ID: 21233840 [TBL] [Abstract][Full Text] [Related]
4. Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression. Liu CY; Huang TT; Chen YT; Chen JL; Chu PY; Huang CT; Wang WL; Lau KY; Dai MS; Shiau CW; Tseng LM EBioMedicine; 2019 Feb; 40():263-275. PubMed ID: 30651219 [TBL] [Abstract][Full Text] [Related]
5. Overexpression of PP2A inhibitor SET oncoprotein is associated with tumor progression and poor prognosis in human non-small cell lung cancer. Liu H; Gu Y; Wang H; Yin J; Zheng G; Zhang Z; Lu M; Wang C; He Z Oncotarget; 2015 Jun; 6(17):14913-25. PubMed ID: 25945834 [TBL] [Abstract][Full Text] [Related]
6. Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors. Smith AM; Dun MD; Lee EM; Harrison C; Kahl R; Flanagan H; Panicker N; Mashkani B; Don AS; Morris J; Toop H; Lock RB; Powell JA; Thomas D; Guthridge MA; Moore A; Ashman LK; Skelding KA; Enjeti A; Verrills NM Oncotarget; 2016 Jul; 7(30):47465-47478. PubMed ID: 27329844 [TBL] [Abstract][Full Text] [Related]
7. Cucurbitacin B induces inhibitory effects via the CIP2A/PP2A/C-KIT signaling axis in t(8;21) acute myeloid leukemia. Ma W; Xiang Y; Yang R; Zhang T; Xu J; Wu Y; Liu X; Xiang K; Zhao H; Liu Y; Si Y J Pharmacol Sci; 2019 Apr; 139(4):304-310. PubMed ID: 30852180 [TBL] [Abstract][Full Text] [Related]
8. Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia. Cristóbal I; Garcia-Orti L; Cirauqui C; Cortes-Lavaud X; García-Sánchez MA; Calasanz MJ; Odero MD Haematologica; 2012 Apr; 97(4):543-50. PubMed ID: 22133779 [TBL] [Abstract][Full Text] [Related]
9. Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia. Arriazu E; Pippa R; Odero MD Front Oncol; 2016; 6():78. PubMed ID: 27092295 [TBL] [Abstract][Full Text] [Related]
11. The interaction of SET and protein phosphatase 2A as target for cancer therapy. Dacol EC; Wang S; Chen Y; Lepique AP Biochim Biophys Acta Rev Cancer; 2021 Aug; 1876(1):188578. PubMed ID: 34116173 [TBL] [Abstract][Full Text] [Related]
12. SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML. Di Mambro A; Arroyo-Berdugo Y; Fioretti T; Randles M; Cozzuto L; Rajeeve V; Cevenini A; Austin MJ; Esposito G; Ponomarenko J; Lucas CM; Cutillas P; Gribben J; Williams O; Calle Y; Patel B; Esposito MT Oncogene; 2023 Dec; 42(50):3670-3683. PubMed ID: 37891368 [TBL] [Abstract][Full Text] [Related]
13. Reactivating PP2A by FTY720 as a novel therapy for AML with C-KIT tyrosine kinase domain mutation. Yang Y; Huang Q; Lu Y; Li X; Huang S J Cell Biochem; 2012 Apr; 113(4):1314-22. PubMed ID: 22109829 [TBL] [Abstract][Full Text] [Related]
14. [Influence of PP2A activator on proliferation of HL-60 cells and analysis of PP2A activity changes in patients with acute myeloid leukemia]. Yang Y; Li XQ; Huang Q; Huang SA Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2011 Jun; 19(3):594-7. PubMed ID: 21729530 [TBL] [Abstract][Full Text] [Related]
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17. Novel B55α-PP2A mutations in AML promote AKT T308 phosphorylation and sensitivity to AKT inhibitor-induced growth arrest. Shouse G; de Necochea-Campion R; Mirshahidi S; Liu X; Chen CS Oncotarget; 2016 Sep; 7(38):61081-61092. PubMed ID: 27531894 [TBL] [Abstract][Full Text] [Related]
18. PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia. Goswami S; Mani R; Nunes J; Chiang CL; Zapolnik K; Hu E; Frissora F; Mo X; Walker LA; Yan P; Bundschuh R; Beaver L; Devine R; Tsai YT; Ventura A; Xie Z; Chen M; Lapalombella R; Walker A; Mims A; Larkin K; Grieselhuber N; Bennett C; Phelps M; Hertlein E; Behbehani G; Vasu S; Byrd JC; Muthusamy N Blood; 2022 Mar; 139(9):1340-1358. PubMed ID: 34788382 [TBL] [Abstract][Full Text] [Related]
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20. Low expression of PP2A regulatory subunit B55α is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients. Ruvolo PP; Qui YH; Coombes KR; Zhang N; Ruvolo VR; Borthakur G; Konopleva M; Andreeff M; Kornblau SM Leukemia; 2011 Nov; 25(11):1711-7. PubMed ID: 21660042 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]