BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 31915197)

  • 1. Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma.
    Mondello P; Tadros S; Teater M; Fontan L; Chang AY; Jain N; Yang H; Singh S; Ying HY; Chu CS; Ma MCJ; Toska E; Alig S; Durant M; de Stanchina E; Ghosh S; Mottok A; Nastoupil L; Neelapu SS; Weigert O; Inghirami G; Baselga J; Younes A; Yee C; Dogan A; Scheinberg DA; Roeder RG; Melnick AM; Green MR
    Cancer Discov; 2020 Mar; 10(3):440-459. PubMed ID: 31915197
    [No Abstract]   [Full Text] [Related]  

  • 2. CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
    Jiang Y; Ortega-Molina A; Geng H; Ying HY; Hatzi K; Parsa S; McNally D; Wang L; Doane AS; Agirre X; Teater M; Meydan C; Li Z; Poloway D; Wang S; Ennishi D; Scott DW; Stengel KR; Kranz JE; Holson E; Sharma S; Young JW; Chu CS; Roeder RG; Shaknovich R; Hiebert SW; Gascoyne RD; Tam W; Elemento O; Wendel HG; Melnick AM
    Cancer Discov; 2017 Jan; 7(1):38-53. PubMed ID: 27733359
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HDAC3 Inhibition Upregulates PD-L1 Expression in B-Cell Lymphomas and Augments the Efficacy of Anti-PD-L1 Therapy.
    Deng S; Hu Q; Zhang H; Yang F; Peng C; Huang C
    Mol Cancer Ther; 2019 May; 18(5):900-908. PubMed ID: 30824609
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting HDAC3 in CREBBP-Mutant Lymphomas Counterstrikes Unopposed Enhancer Deacetylation of B-cell Signaling and Immune Response Genes.
    Höpken UE
    Cancer Discov; 2017 Jan; 7(1):14-16. PubMed ID: 28062671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma.
    Zhang J; Vlasevska S; Wells VA; Nataraj S; Holmes AB; Duval R; Meyer SN; Mo T; Basso K; Brindle PK; Hussein S; Dalla-Favera R; Pasqualucci L
    Cancer Discov; 2017 Mar; 7(3):322-337. PubMed ID: 28069569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inactivating mutations of acetyltransferase genes in B-cell lymphoma.
    Pasqualucci L; Dominguez-Sola D; Chiarenza A; Fabbri G; Grunn A; Trifonov V; Kasper LH; Lerach S; Tang H; Ma J; Rossi D; Chadburn A; Murty VV; Mullighan CG; Gaidano G; Rabadan R; Brindle PK; Dalla-Favera R
    Nature; 2011 Mar; 471(7337):189-95. PubMed ID: 21390126
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.
    Cerchietti LC; Hatzi K; Caldas-Lopes E; Yang SN; Figueroa ME; Morin RD; Hirst M; Mendez L; Shaknovich R; Cole PA; Bhalla K; Gascoyne RD; Marra M; Chiosis G; Melnick A
    J Clin Invest; 2010 Dec; 120(12):4569-82. PubMed ID: 21041953
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced histone H3 acetylation of the PD-L1 promoter via the COP1/c-Jun/HDAC3 axis is required for PD-L1 expression in drug-resistant cancer cells.
    Wang H; Fu C; Du J; Wang H; He R; Yin X; Li H; Li X; Wang H; Li K; Zheng L; Liu Z; Qiu Y
    J Exp Clin Cancer Res; 2020 Feb; 39(1):29. PubMed ID: 32024543
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
    Matthews GM; Mehdipour P; Cluse LA; Falkenberg KJ; Wang E; Roth M; Santoro F; Vidacs E; Stanley K; House CM; Rusche JR; Vakoc CR; Zuber J; Minucci S; Johnstone RW
    Blood; 2015 Nov; 126(21):2392-403. PubMed ID: 26447190
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer.
    Adeegbe DO; Liu Y; Lizotte PH; Kamihara Y; Aref AR; Almonte C; Dries R; Li Y; Liu S; Wang X; Warner-Hatten T; Castrillon J; Yuan GC; Poudel-Neupane N; Zhang H; Guerriero JL; Han S; Awad MM; Barbie DA; Ritz J; Jones SS; Hammerman PS; Bradner J; Quayle SN; Wong KK
    Cancer Discov; 2017 Aug; 7(8):852-867. PubMed ID: 28408401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma.
    Desmots F; Roussel M; Pangault C; Llamas-Gutierrez F; Pastoret C; Guiheneuf E; Le Priol J; Camara-Clayette V; Caron G; Henry C; Belaud-Rotureau MA; Godmer P; Lamy T; Jardin F; Tarte K; Ribrag V; Fest T
    Clin Cancer Res; 2019 Jan; 25(2):735-746. PubMed ID: 30348636
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppression of BCL6 function by HDAC inhibitor mediated acetylation and chromatin modification enhances BET inhibitor effects in B-cell lymphoma cells.
    Cortiguera MG; García-Gaipo L; Wagner SD; León J; Batlle-López A; Delgado MD
    Sci Rep; 2019 Nov; 9(1):16495. PubMed ID: 31712669
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.
    Lue JK; Prabhu SA; Liu Y; Gonzalez Y; Verma A; Mundi PS; Abshiru N; Camarillo JM; Mehta S; Chen EI; Qiao C; Nandakumar R; Cremers S; Kelleher NL; Elemento O; Amengual JE
    Clin Cancer Res; 2019 Sep; 25(17):5271-5283. PubMed ID: 30979734
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HDAC is indispensable for IFN-γ-induced B7-H1 expression in gastric cancer.
    Deng R; Zhang P; Liu W; Zeng X; Ma X; Shi L; Wang T; Yin Y; Chang W; Zhang P; Wang G; Tao K
    Clin Epigenetics; 2018 Dec; 10(1):153. PubMed ID: 30537988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.
    Hashwah H; Schmid CA; Kasser S; Bertram K; Stelling A; Manz MG; Müller A
    Proc Natl Acad Sci U S A; 2017 Sep; 114(36):9701-9706. PubMed ID: 28831000
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation.
    Green MR; Kihira S; Liu CL; Nair RV; Salari R; Gentles AJ; Irish J; Stehr H; Vicente-Dueñas C; Romero-Camarero I; Sanchez-Garcia I; Plevritis SK; Arber DA; Batzoglou S; Levy R; Alizadeh AA
    Proc Natl Acad Sci U S A; 2015 Mar; 112(10):E1116-25. PubMed ID: 25713363
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.
    Veazey KJ; Cheng D; Lin K; Villarreal OD; Gao G; Perez-Oquendo M; Van HT; Stratton SA; Green M; Xu H; Lu Y; Bedford MT; Santos MA
    Leukemia; 2020 Dec; 34(12):3269-3285. PubMed ID: 32576962
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis and therapeutic targeting of the EP300 and CREBBP acetyltransferases in anaplastic large cell lymphoma and Hodgkin lymphoma.
    Wei W; Song Z; Chiba M; Wu W; Jeong S; Zhang JP; Kadin ME; Nakagawa M; Yang Y
    Leukemia; 2023 Feb; 37(2):396-407. PubMed ID: 36456744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
    Que Y; Zhang XL; Liu ZX; Zhao JJ; Pan QZ; Wen XZ; Xiao W; Xu BS; Hong DC; Guo TH; Shen LJ; Fan WJ; Chen HY; Weng DS; Xu HR; Zhou PH; Zhang YZ; Niu XH; Zhang X
    J Immunother Cancer; 2021 Feb; 9(2):. PubMed ID: 33637599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone deacetylase 3 controls a transcriptional network required for B cell maturation.
    Stengel KR; Bhaskara S; Wang J; Liu Q; Ellis JD; Sampathi S; Hiebert SW
    Nucleic Acids Res; 2019 Nov; 47(20):10612-10627. PubMed ID: 31586401
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.