BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 31918006)

  • 1. A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction.
    Subramanian C; Yao J; Frank MW; Rock CO; Jackowski S
    Biochim Biophys Acta Mol Basis Dis; 2020 May; 1866(5):165663. PubMed ID: 31918006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.
    Zano SP; Pate C; Frank M; Rock CO; Jackowski S
    Mol Genet Metab; 2015 Dec; 116(4):281-8. PubMed ID: 26549575
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pantothenate Kinase Activation Restores Brain Coenzyme A in a Mouse Model of Pantothenate Kinase-Associated Neurodegeneration.
    Subramanian C; Frank MW; Sukhun R; Henry CE; Wade A; Harden ME; Rao S; Tangallapally R; Yun MK; White SW; Lee RE; Sinha U; Rock CO; Jackowski S
    J Pharmacol Exp Ther; 2024 Jan; 388(1):171-180. PubMed ID: 37875310
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A therapeutic approach to pantothenate kinase associated neurodegeneration.
    Sharma LK; Subramanian C; Yun MK; Frank MW; White SW; Rock CO; Lee RE; Jackowski S
    Nat Commun; 2018 Oct; 9(1):4399. PubMed ID: 30352999
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proton magnetic resonance spectroscopy detects cerebral metabolic derangement in a mouse model of brain coenzyme a deficiency.
    Li Y; Steinberg J; Coleman Z; Wang S; Subramanian C; Li Y; Patay Z; Akers W; Rock CO; Jackowski S; Bagga P
    J Transl Med; 2022 Feb; 20(1):103. PubMed ID: 35197056
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.
    Garcia M; Leonardi R; Zhang YM; Rehg JE; Jackowski S
    PLoS One; 2012; 7(7):e40871. PubMed ID: 22815849
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Potential Citrate Shunt in Erythrocytes of PKAN Patients Caused by Mutations in Pantothenate Kinase 2.
    Werning M; Dobretzberger V; Brenner M; Müllner EW; Mlynek G; Djinovic-Carugo K; Baron DM; Fragner L; Bischoff AT; Büchner B; Klopstock T; Weckwerth W; Salzer U
    Biomolecules; 2022 Feb; 12(2):. PubMed ID: 35204826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice.
    Shumar SA; Fagone P; Alfonso-Pecchio A; Gray JT; Rehg JE; Jackowski S; Leonardi R
    PLoS One; 2015; 10(6):e0130013. PubMed ID: 26052948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pantothenate kinase-associated neurodegeneration: insights from a Drosophila model.
    Wu Z; Li C; Lv S; Zhou B
    Hum Mol Genet; 2009 Oct; 18(19):3659-72. PubMed ID: 19602483
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives.
    Álvarez-Córdoba M; Talaverón-Rey M; Villalón-García I; Povea-Cabello S; Suárez-Rivero JM; Suárez-Carrillo A; Munuera-Cabeza M; Salas JJ; Sánchez-Alcázar JA
    Orphanet J Rare Dis; 2021 May; 16(1):201. PubMed ID: 33952316
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation.
    Álvarez-Córdoba M; Fernández Khoury A; Villanueva-Paz M; Gómez-Navarro C; Villalón-García I; Suárez-Rivero JM; Povea-Cabello S; de la Mata M; Cotán D; Talaverón-Rey M; Pérez-Pulido AJ; Salas JJ; Pérez-Villegas EM; Díaz-Quintana A; Armengol JA; Sánchez-Alcázar JA
    Mol Neurobiol; 2019 May; 56(5):3638-3656. PubMed ID: 30173408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2.
    Kotzbauer PT; Truax AC; Trojanowski JQ; Lee VM
    J Neurosci; 2005 Jan; 25(3):689-98. PubMed ID: 15659606
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alpha-lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels.
    Talaverón-Rey M; Álvarez-Córdoba M; Villalón-García I; Povea-Cabello S; Suárez-Rivero JM; Gómez-Fernández D; Romero-González A; Suárez-Carrillo A; Munuera-Cabeza M; Cilleros-Holgado P; Reche-López D; Piñero-Pérez R; Sánchez-Alcázar JA
    Orphanet J Rare Dis; 2023 Apr; 18(1):80. PubMed ID: 37046296
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exploring Yeast as a Study Model of Pantothenate Kinase-Associated Neurodegeneration and for the Identification of Therapeutic Compounds.
    Ceccatelli Berti C; Gilea AI; De Gregorio MA; Goffrini P
    Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33396642
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration.
    Orellana DI; Santambrogio P; Rubio A; Yekhlef L; Cancellieri C; Dusi S; Giannelli SG; Venco P; Mazzara PG; Cozzi A; Ferrari M; Garavaglia B; Taverna S; Tiranti V; Broccoli V; Levi S
    EMBO Mol Med; 2016 Oct; 8(10):1197-1211. PubMed ID: 27516453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease.
    Zizioli D; Tiso N; Guglielmi A; Saraceno C; Busolin G; Giuliani R; Khatri D; Monti E; Borsani G; Argenton F; Finazzi D
    Neurobiol Dis; 2016 Jan; 85():35-48. PubMed ID: 26476142
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes.
    Rock CO; Karim MA; Zhang YM; Jackowski S
    Gene; 2002 May; 291(1-2):35-43. PubMed ID: 12095677
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.
    Campanella A; Privitera D; Guaraldo M; Rovelli E; Barzaghi C; Garavaglia B; Santambrogio P; Cozzi A; Levi S
    Hum Mol Genet; 2012 Sep; 21(18):4049-59. PubMed ID: 22692681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cardiac PANK1 deletion exacerbates ventricular dysfunction during pressure overload.
    Audam TN; Howard CM; Garrett LF; Zheng YW; Bradley JA; Brittian KR; Frank MW; Fulghum KL; Pólos M; Herczeg S; Merkely B; Radovits T; Uchida S; Hill BG; Dassanayaka S; Jackowski S; Jones SP
    Am J Physiol Heart Circ Physiol; 2021 Oct; 321(4):H784-H797. PubMed ID: 34533403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bi-Allelic Mutations in Zebrafish
    Mignani L; Zizioli D; Khatri D; Facchinello N; Schiavone M; De Palma G; Finazzi D
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361705
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.