BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 31918031)

  • 1. Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death.
    Britti E; Ros J; Esteras N; Abramov AY
    Cell Calcium; 2020 Mar; 86():102150. PubMed ID: 31918031
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial Calcium Deregulation in the Mechanism of Beta-Amyloid and Tau Pathology.
    Esteras N; Abramov AY
    Cells; 2020 Sep; 9(9):. PubMed ID: 32967303
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRRK2 deficiency induced mitochondrial Ca
    Ludtmann MHR; Kostic M; Horne A; Gandhi S; Sekler I; Abramov AY
    Cell Death Dis; 2019 Mar; 10(4):265. PubMed ID: 30890692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration.
    Esteras N; Rohrer JD; Hardy J; Wray S; Abramov AY
    Redox Biol; 2017 Aug; 12():410-422. PubMed ID: 28319892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.
    Iovino M; Agathou S; González-Rueda A; Del Castillo Velasco-Herrera M; Borroni B; Alberici A; Lynch T; O'Dowd S; Geti I; Gaffney D; Vallier L; Paulsen O; Káradóttir RT; Spillantini MG
    Brain; 2015 Nov; 138(Pt 11):3345-59. PubMed ID: 26220942
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage-gated calcium channels and NADPH oxidase.
    Esteras N; Kundel F; Amodeo GF; Pavlov EV; Klenerman D; Abramov AY
    FEBS J; 2021 Jan; 288(1):127-141. PubMed ID: 32338825
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.
    García-León JA; Cabrera-Socorro A; Eggermont K; Swijsen A; Terryn J; Fazal R; Nami F; Ordovás L; Quiles A; Lluis F; Serneels L; Wierda K; Sierksma A; Kreir M; Pestana F; Van Damme P; De Strooper B; Thorrez L; Ebneth A; Verfaillie CM
    Alzheimers Dement; 2018 Oct; 14(10):1261-1280. PubMed ID: 30036493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations.
    Biswas MHU; Almeida S; Lopez-Gonzalez R; Mao W; Zhang Z; Karydas A; Geschwind MD; Biernat J; Mandelkow EM; Futai K; Miller BL; Gao FB
    Stem Cell Reports; 2016 Sep; 7(3):316-324. PubMed ID: 27594586
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MAPT genotype-dependent mitochondrial aberration and ROS production trigger dysfunction and death in cortical neurons of patients with hereditary FTLD.
    Korn L; Speicher AM; Schroeter CB; Gola L; Kaehne T; Engler A; Disse P; Fernández-Orth J; Csatári J; Naumann M; Seebohm G; Meuth SG; Schöler HR; Wiendl H; Kovac S; Pawlowski M
    Redox Biol; 2023 Feb; 59():102597. PubMed ID: 36599286
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CGP37157, an inhibitor of the mitochondrial Na+/Ca2+ exchanger, protects neurons from excitotoxicity by blocking voltage-gated Ca2+ channels.
    Ruiz A; Alberdi E; Matute C
    Cell Death Dis; 2014 Apr; 5(4):e1156. PubMed ID: 24722281
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons.
    Oakley DH; Klickstein N; Commins C; Chung M; Dujardin S; Bennett RE; Hyman BT; Frosch MP
    J Neurosci; 2021 May; 41(19):4335-4348. PubMed ID: 33893219
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs.
    Nakamura M; Shiozawa S; Tsuboi D; Amano M; Watanabe H; Maeda S; Kimura T; Yoshimatsu S; Kisa F; Karch CM; Miyasaka T; Takashima A; Sahara N; Hisanaga SI; Ikeuchi T; Kaibuchi K; Okano H
    Stem Cell Reports; 2019 Oct; 13(4):684-699. PubMed ID: 31543469
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons.
    Imamura K; Sahara N; Kanaan NM; Tsukita K; Kondo T; Kutoku Y; Ohsawa Y; Sunada Y; Kawakami K; Hotta A; Yawata S; Watanabe D; Hasegawa M; Trojanowski JQ; Lee VM; Suhara T; Higuchi M; Inoue H
    Sci Rep; 2016 Oct; 6():34904. PubMed ID: 27721502
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.
    Wren MC; Zhao J; Liu CC; Murray ME; Atagi Y; Davis MD; Fu Y; Okano HJ; Ogaki K; Strongosky AJ; Tacik P; Rademakers R; Ross OA; Dickson DW; Wszolek ZK; Kanekiyo T; Bu G
    Mol Neurodegener; 2015 Sep; 10():46. PubMed ID: 26373282
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy.
    Cheng C; Reis SA; Adams ET; Fass DM; Angus SP; Stuhlmiller TJ; Richardson J; Olafson H; Wang ET; Patnaik D; Beauchamp RL; Feldman DA; Silva MC; Sur M; Johnson GL; Ramesh V; Miller BL; Temple S; Kosik KS; Dickerson BC; Haggarty SJ
    Sci Rep; 2021 Aug; 11(1):17029. PubMed ID: 34426604
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric Regulation of NCLX by Mitochondrial Membrane Potential Links the Metabolic State and Ca
    Kostic M; Katoshevski T; Sekler I
    Cell Rep; 2018 Dec; 25(12):3465-3475.e4. PubMed ID: 30566870
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Brief update on different roles of tau in neurodegeneration.
    Ittner A; Ke YD; van Eersel J; Gladbach A; Götz J; Ittner LM
    IUBMB Life; 2011 Jul; 63(7):495-502. PubMed ID: 21698753
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Imaging of mitochondrial Ca2+ dynamics in astrocytes using cell-specific mitochondria-targeted GCaMP5G/6s: mitochondrial Ca2+ uptake and cytosolic Ca2+ availability via the endoplasmic reticulum store.
    Li H; Wang X; Zhang N; Gottipati MK; Parpura V; Ding S
    Cell Calcium; 2014 Dec; 56(6):457-66. PubMed ID: 25443655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tau localises within mitochondrial sub-compartments and its caspase cleavage affects ER-mitochondria interactions and cellular Ca
    Cieri D; Vicario M; Vallese F; D'Orsi B; Berto P; Grinzato A; Catoni C; De Stefani D; Rizzuto R; Brini M; Calì T
    Biochim Biophys Acta Mol Basis Dis; 2018 Oct; 1864(10):3247-3256. PubMed ID: 30006151
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits.
    Koss DJ; Robinson L; Mietelska-Porowska A; Gasiorowska A; Sepčić K; Turk T; Jaspars M; Niewiadomska G; Scott RH; Platt B; Riedel G
    Cell Mol Life Sci; 2015 Dec; 72(23):4613-32. PubMed ID: 26070304
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.