191 related articles for article (PubMed ID: 31929539)
1. Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho.
Chen CD; Li Y; Chen AK; Rudy MA; Nasse JS; Zeldich E; Polanco TJ; Abraham CR
PLoS One; 2020; 15(1):e0226382. PubMed ID: 31929539
[TBL] [Abstract][Full Text] [Related]
2. Identification of cleavage sites leading to the shed form of the anti-aging protein klotho.
Chen CD; Tung TY; Liang J; Zeldich E; Tucker Zhou TB; Turk BE; Abraham CR
Biochemistry; 2014 Sep; 53(34):5579-87. PubMed ID: 25110992
[TBL] [Abstract][Full Text] [Related]
3. Shedding of klotho by ADAMs in the kidney.
van Loon EP; Pulskens WP; van der Hagen EA; Lavrijsen M; Vervloet MG; van Goor H; Bindels RJ; Hoenderop JG
Am J Physiol Renal Physiol; 2015 Aug; 309(4):F359-68. PubMed ID: 26155844
[TBL] [Abstract][Full Text] [Related]
4. Tumor Suppressor Activity of Klotho in Breast Cancer Is Revealed by Structure-Function Analysis.
Ligumsky H; Rubinek T; Merenbakh-Lamin K; Yeheskel A; Sertchook R; Shahmoon S; Aviel-Ronen S; Wolf I
Mol Cancer Res; 2015 Oct; 13(10):1398-407. PubMed ID: 26113466
[TBL] [Abstract][Full Text] [Related]
5. N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.
Esapa CT; Hannan FM; Babinsky VN; Potter P; Thomas GP; Croucher PI; Brown MA; Brown SD; Cox RD; Thakker RV
PLoS One; 2015; 10(4):e0122650. PubMed ID: 25860694
[TBL] [Abstract][Full Text] [Related]
6. Subtle Difference Generates Big Dissimilarity: Comparison of Enzymatic Activity in KL1 and KL2 Domains of Lancelet Klotho.
Ma Z; Qu B; Zhong S; Yao L; Gao Z; Zhang S
Mar Biotechnol (NY); 2019 Aug; 21(4):448-462. PubMed ID: 31053952
[TBL] [Abstract][Full Text] [Related]
7. Modeled structural basis for the recognition of α2-3-sialyllactose by soluble Klotho.
Wright JD; An SW; Xie J; Yoon J; Nischan N; Kohler JJ; Oliver N; Lim C; Huang CL
FASEB J; 2017 Aug; 31(8):3574-3586. PubMed ID: 28442546
[TBL] [Abstract][Full Text] [Related]
8. α-Klotho's effects on mineral homeostasis are fibroblast growth factor-23 dependent.
Erben RG
Curr Opin Nephrol Hypertens; 2018 Jul; 27(4):229-235. PubMed ID: 29851418
[TBL] [Abstract][Full Text] [Related]
9. KL1 internal repeat mediates klotho tumor suppressor activities and inhibits bFGF and IGF-I signaling in pancreatic cancer.
Abramovitz L; Rubinek T; Ligumsky H; Bose S; Barshack I; Avivi C; Kaufman B; Wolf I
Clin Cancer Res; 2011 Jul; 17(13):4254-66. PubMed ID: 21571866
[TBL] [Abstract][Full Text] [Related]
10. Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.
Goetz R; Nakada Y; Hu MC; Kurosu H; Wang L; Nakatani T; Shi M; Eliseenkova AV; Razzaque MS; Moe OW; Kuro-o M; Mohammadi M
Proc Natl Acad Sci U S A; 2010 Jan; 107(1):407-12. PubMed ID: 19966287
[TBL] [Abstract][Full Text] [Related]
11. Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17.
Chen CD; Podvin S; Gillespie E; Leeman SE; Abraham CR
Proc Natl Acad Sci U S A; 2007 Dec; 104(50):19796-801. PubMed ID: 18056631
[TBL] [Abstract][Full Text] [Related]
12. α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.
Chen G; Liu Y; Goetz R; Fu L; Jayaraman S; Hu MC; Moe OW; Liang G; Li X; Mohammadi M
Nature; 2018 Jan; 553(7689):461-466. PubMed ID: 29342138
[TBL] [Abstract][Full Text] [Related]
13. Shedding of Klotho: Functional Implications in Chronic Kidney Disease and Associated Vascular Disease.
Saar-Kovrov V; Donners MMPC; van der Vorst EPC
Front Cardiovasc Med; 2020; 7():617842. PubMed ID: 33585584
[TBL] [Abstract][Full Text] [Related]
14. Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease.
Zhong X; Jagarlapudi S; Weng Y; Ly M; Rouse JC; McClure K; Ishino T; Zhang Y; Sousa E; Cohen J; Tzvetkova B; Cote K; Scarcelli JJ; Johnson K; Palandra J; Apgar JR; Yaddanapudi S; Gonzalez-Villalobos RA; Opsahl AC; Lam K; Yao Q; Duan W; Sievers A; Zhou J; Ferguson D; D'Antona A; Zollner R; Zhu HL; Kriz R; Lin L; Clerin V
J Biol Chem; 2020 Mar; 295(10):3115-3133. PubMed ID: 32005658
[TBL] [Abstract][Full Text] [Related]
15. Differential regulation of renal Klotho and FGFR1 in normal and uremic rats.
Muñoz-Castañeda JR; Herencia C; Pendón-Ruiz de Mier MV; Rodriguez-Ortiz ME; Diaz-Tocados JM; Vergara N; Martínez-Moreno JM; Salmerón MD; Richards WG; Felsenfeld A; Kuro-O M; Almadén Y; Rodríguez M
FASEB J; 2017 Sep; 31(9):3858-3867. PubMed ID: 28515153
[TBL] [Abstract][Full Text] [Related]
16. The Hormone KL1: A Regulator of Breast Cancer Cell Metabolism.
Davidov B; Shmulevich R; Shabtay A; Rubinek T; Wolf I
Isr Med Assoc J; 2019 Jul; 21(7):504. PubMed ID: 31507133
[TBL] [Abstract][Full Text] [Related]
17. Klotho converts canonical FGF receptor into a specific receptor for FGF23.
Urakawa I; Yamazaki Y; Shimada T; Iijima K; Hasegawa H; Okawa K; Fujita T; Fukumoto S; Yamashita T
Nature; 2006 Dec; 444(7120):770-4. PubMed ID: 17086194
[TBL] [Abstract][Full Text] [Related]
18. [Role of parathyroid hormone in Klotho-FGF23 system].
Kimura T; Shiizaki K; Kuro-O M
Clin Calcium; 2016 Jun; 26(6):859-66. PubMed ID: 27230841
[TBL] [Abstract][Full Text] [Related]
19. KL1 Domain of Longevity Factor Klotho Mimics the Metabolome of Cognitive Stimulation and Enhances Cognition in Young and Aging Mice.
Gupta S; Moreno AJ; Wang D; Leon J; Chen C; Hahn O; Poon Y; Greenberg K; David N; Wyss-Coray T; Raftery D; Promislow DEL; Dubal DB
J Neurosci; 2022 May; 42(19):4016-4025. PubMed ID: 35428698
[TBL] [Abstract][Full Text] [Related]
20. Targeted inhibition of Klotho binding to fibroblast growth factor 23 prevents hypophosphetemia.
Fakhar M; Rashid S
J Mol Graph Model; 2017 Aug; 75():9-19. PubMed ID: 28501532
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
