These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 31930237)

  • 1. Kinetic analysis of sequential metabolism of triazolam and its extrapolation to humans using an entero-hepatic two-organ microphysiological system.
    Arakawa H; Sugiura S; Kawanishi T; Shin K; Toyoda H; Satoh T; Sakai Y; Kanamori T; Kato Y
    Lab Chip; 2020 Feb; 20(3):537-547. PubMed ID: 31930237
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of the hepatic metabolism of triazolam in wild-type andCyp3a-knockout mice for understanding CYP3A-mediated metabolism inCYP3A-humanised mice
    Minegishi G; Kazuki Y; Yamasaki Y; Okuya F; Akita H; Oshimura M; Kobayashi K
    Xenobiotica; 2019 Nov; 49(11):1303-1310. PubMed ID: 30561249
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
    Rubiano A; Indapurkar A; Yokosawa R; Miedzik A; Rosenzweig B; Arefin A; Moulin CM; Dame K; Hartman N; Volpe DA; Matta MK; Hughes DJ; Strauss DG; Kostrzewski T; Ribeiro AJS
    Clin Transl Sci; 2021 May; 14(3):1049-1061. PubMed ID: 33382907
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LC-MS determination of triazolam and its hydroxy metabolites in mouse dried blood spots: application to transgenic mouse pharmacokinetic studies.
    Kole P; Rao A; Kurawattimath V; Mandlekar S
    Bioanalysis; 2017 Jul; 9(13):987-1000. PubMed ID: 28692308
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam.
    Kuze J; Mutoh T; Takenaka T; Oda N; Hanioka N; Narimatsu S
    Xenobiotica; 2013 Jul; 43(7):598-606. PubMed ID: 23282066
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of age on in vitro triazolam biotransformation in male human liver microsomes.
    Patki KC; von Moltke LL; Harmatz JS; Hesse LM; Court MH; Greenblatt DJ
    J Pharmacol Exp Ther; 2004 Mar; 308(3):874-9. PubMed ID: 14634046
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Liver Microphysiological Systems for Predicting and Evaluating Drug Effects.
    Ribeiro AJS; Yang X; Patel V; Madabushi R; Strauss DG
    Clin Pharmacol Ther; 2019 Jul; 106(1):139-147. PubMed ID: 30993668
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment.
    Marin TM; Indolfo NC; Rocco SA; de Carvalho M; Dias MM; Vasconcelos Bento GI; Bortot LO; Schuck DC; Lorencini M; Pagani E
    J Vis Exp; 2020 Dec; (166):. PubMed ID: 33346185
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A thermoplastic microfluidic microphysiological system to recapitulate hepatic function and multicellular interactions.
    Bale SS; Manoppo A; Thompson R; Markoski A; Coppeta J; Cain B; Haroutunian N; Newlin V; Spencer A; Azizgolshani H; Lu M; Gosset J; Keegan P; Charest JL
    Biotechnol Bioeng; 2019 Dec; 116(12):3409-3420. PubMed ID: 30963546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of CYP3A enzymes in the biotransformation of triazolam in rat liver.
    Warrington JS; Greenblatt DJ; Von Moltke LL
    Xenobiotica; 2004 May; 34(5):463-71. PubMed ID: 15370962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of oral contraceptives on triazolam, temazepam, alprazolam, and lorazepam kinetics.
    Stoehr GP; Kroboth PD; Juhl RP; Wender DB; Phillips JP; Smith RB
    Clin Pharmacol Ther; 1984 Nov; 36(5):683-90. PubMed ID: 6149030
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetic modeling of the dosing interval dependency for the interaction between itraconazole and triazolam.
    Toi A; Ohtani H; Tsujimoto M; Sawada Y
    Int J Clin Pharmacol Ther; 2010 Jun; 48(6):356-66. PubMed ID: 20497744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Application of a gut-liver-on-a-chip device and mechanistic modelling to the quantitative
    Milani N; Parrott N; Ortiz Franyuti D; Godoy P; Galetin A; Gertz M; Fowler S
    Lab Chip; 2022 Jul; 22(15):2853-2868. PubMed ID: 35833849
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism of 8-chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo [4,3-alpha] [1,4]benzodiazepine, triazolam, a new central depressant. II. Identification and determination of metabolites in rats and dogs.
    Kitagawa H; Esumi Y; Kurosawa S; Sekine S; Yokoshima T
    Xenobiotica; 1979 Jul; 9(7):429-39. PubMed ID: 40351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms.
    Perloff MD; von Moltke LL; Court MH; Kotegawa T; Shader RI; Greenblatt DJ
    J Pharmacol Exp Ther; 2000 Feb; 292(2):618-28. PubMed ID: 10640299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ethanol inhibits in-vitro metabolism of nifedipine, triazolam and testosterone in human liver microsomes.
    Patki KC; Greenblatt DJ; von Moltke LL
    J Pharm Pharmacol; 2004 Aug; 56(8):963-6. PubMed ID: 15285839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of triazolam and ketoconazole in P-glycoprotein-deficient mice.
    von Moltke LL; Granda BW; Grassi JM; Perloff MD; Vishnuvardhan D; Greenblatt DJ
    Drug Metab Dispos; 2004 Aug; 32(8):800-4. PubMed ID: 15258104
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies.
    Maass C; Dallas M; LaBarge ME; Shockley M; Valdez J; Geishecker E; Stokes CL; Griffith LG; Cirit M
    Sci Rep; 2018 May; 8(1):8015. PubMed ID: 29789564
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Physiologically based predictions of the impact of inhibition of intestinal and hepatic metabolism on human pharmacokinetics of CYP3A substrates.
    Fenneteau F; Poulin P; Nekka F
    J Pharm Sci; 2010 Jan; 99(1):486-514. PubMed ID: 19479982
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse
    Kobayashi K; Minegishi G; Kuriyama N; Miyajima A; Abe S; Kazuki K; Kazuki Y
    Drug Metab Dispos; 2023 Feb; 51(2):174-182. PubMed ID: 36379710
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.