99 related articles for article (PubMed ID: 31930396)
1. Inactivation of TRP53, PTEN, RB1, and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis.
Shi M; Whorton AE; Sekulovski N; Paquet M; MacLean JA; Song Y; Van Dyke T; Hayashi K
Biol Reprod; 2020 Apr; 102(5):1055-1064. PubMed ID: 31930396
[TBL] [Abstract][Full Text] [Related]
2. Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.
Mullany LK; Fan HY; Liu Z; White LD; Marshall A; Gunaratne P; Anderson ML; Creighton CJ; Xin L; Deavers M; Wong KK; Richards JS
Oncogene; 2011 Aug; 30(32):3522-36. PubMed ID: 21423204
[TBL] [Abstract][Full Text] [Related]
3. The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice.
Kim J; Coffey DM; Ma L; Matzuk MM
Endocrinology; 2015 Jun; 156(6):1975-81. PubMed ID: 25815421
[TBL] [Abstract][Full Text] [Related]
4. CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity.
Walton JB; Farquharson M; Mason S; Port J; Kruspig B; Dowson S; Stevenson D; Murphy D; Matzuk M; Kim J; Coffelt S; Blyth K; McNeish IA
Sci Rep; 2017 Dec; 7(1):16827. PubMed ID: 29203787
[TBL] [Abstract][Full Text] [Related]
5. PTEN Loss Expands the Histopathologic Diversity and Lineage Plasticity of Lung Cancers Initiated by Rb1/Trp53 Deletion.
Zhang L; Liu C; Zhang B; Zheng J; Singh PK; Bshara W; Wang J; Gomez EC; Zhang X; Wang Y; Zhu X; Goodrich DW
J Thorac Oncol; 2023 Mar; 18(3):324-338. PubMed ID: 36473627
[TBL] [Abstract][Full Text] [Related]
6. CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.
Walton J; Blagih J; Ennis D; Leung E; Dowson S; Farquharson M; Tookman LA; Orange C; Athineos D; Mason S; Stevenson D; Blyth K; Strathdee D; Balkwill FR; Vousden K; Lockley M; McNeish IA
Cancer Res; 2016 Oct; 76(20):6118-6129. PubMed ID: 27530326
[TBL] [Abstract][Full Text] [Related]
7.
Jia D; Augert A; Kim DW; Eastwood E; Wu N; Ibrahim AH; Kim KB; Dunn CT; Pillai SPS; Gazdar AF; Bolouri H; Park KS; MacPherson D
Cancer Discov; 2018 Nov; 8(11):1422-1437. PubMed ID: 30181244
[No Abstract] [Full Text] [Related]
8. A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells.
Bulanova D; Akimov Y; Senkowski W; Oikkonen J; Gall-Mas L; Timonen S; Elmadani M; Hynninen J; Hautaniemi S; Aittokallio T; Wennerberg K
Sci Adv; 2024 May; 10(21):eadj1564. PubMed ID: 38781347
[TBL] [Abstract][Full Text] [Related]
9. 17β-Estradiol sensitizes ovarian surface epithelium to transformation by suppressing Disabled-2 expression.
Vuong NH; Salah Salah O; Vanderhyden BC
Sci Rep; 2017 Dec; 7(1):16702. PubMed ID: 29196616
[TBL] [Abstract][Full Text] [Related]
10. Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.
Ku SY; Rosario S; Wang Y; Mu P; Seshadri M; Goodrich ZW; Goodrich MM; Labbé DP; Gomez EC; Wang J; Long HW; Xu B; Brown M; Loda M; Sawyers CL; Ellis L; Goodrich DW
Science; 2017 Jan; 355(6320):78-83. PubMed ID: 28059767
[TBL] [Abstract][Full Text] [Related]
11. Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis.
Tseng SH; Park ST; Lam B; Tsai YC; Cheng MA; Farmer E; Xing D; Hung CF
J Immunother Cancer; 2020 Feb; 8(1):. PubMed ID: 32111730
[TBL] [Abstract][Full Text] [Related]
12. E-cadherin loss drives diffuse-type gastric tumorigenesis via EZH2-mediated reprogramming.
Zou G; Huang Y; Zhang S; Ko KP; Kim B; Zhang J; Venkatesan V; Pizzi MP; Fan Y; Jun S; Niu N; Wang H; Song S; Ajani JA; Park JI
J Exp Med; 2024 Apr; 221(4):. PubMed ID: 38411616
[TBL] [Abstract][Full Text] [Related]
13. Deletion of Trp53 and Rb1 in Ctsk-expressing cells drives osteosarcoma progression by activating glucose metabolism and YAP signaling.
Li Y; Yang S; Liu Y; Yang S
MedComm (2020); 2022 Jun; 3(2):e131. PubMed ID: 35615117
[TBL] [Abstract][Full Text] [Related]
14. Intra-Tumoral Nerve-Tracing in a Novel Syngeneic Model of High-Grade Serous Ovarian Carcinoma.
Barr JL; Kruse A; Restaino AC; Tulina N; Stuckelberger S; Vermeer SJ; Williamson CS; Vermeer DW; Madeo M; Stamp J; Bell M; Morgan M; Yoon JY; Mitchell MA; Budina A; Omran DK; Schwartz LE; Drapkin R; Vermeer PD
Cells; 2021 Dec; 10(12):. PubMed ID: 34944001
[TBL] [Abstract][Full Text] [Related]
15. Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells.
Parkhitko AA; Singh A; Hsieh S; Hu Y; Binari R; Lord CJ; Hannenhalli S; Ryan CJ; Perrimon N
PLoS Genet; 2021 Feb; 17(2):e1009354. PubMed ID: 33591981
[TBL] [Abstract][Full Text] [Related]
16. Development of mouse models of angiosarcoma driven by p53.
Salter DM; Griffin M; Muir M; Teo K; Culley J; Smith JR; Gomez-Cuadrado L; Matchett K; Sims AH; Hayward L; Henderson NC; Brunton VG
Dis Model Mech; 2019 Jul; 12(7):. PubMed ID: 31221668
[TBL] [Abstract][Full Text] [Related]
17. Mutant p53 regulates Survivin to foster lung metastasis.
Tang Q; Efe G; Chiarella AM; Leung J; Chen M; Yamazoe T; Su Z; Pitarresi JR; Li J; Islam M; Karakasheva T; Klein-Szanto AJ; Pan S; Hu J; Natsugoe S; Gu W; Stanger BZ; Wong KK; Diehl JA; Bass AJ; Nakagawa H; Murphy ME; Rustgi AK
Genes Dev; 2021 Apr; 35(7-8):528-541. PubMed ID: 33737385
[TBL] [Abstract][Full Text] [Related]
18. Induction of papillary carcinoma in human ovarian surface epithelial cells using combined genetic elements and peritoneal microenvironment.
Zheng J; Mercado-Uribe I; Rosen DG; Chang B; Liu P; Yang G; Malpica A; Naora H; Auersperg N; Mills GB; Bast RC; Liu J
Cell Cycle; 2010 Jan; 9(1):140-6. PubMed ID: 20016289
[TBL] [Abstract][Full Text] [Related]
19. Mice with Trp53 and Rb1 deficiency in chondrocytes spontaneously develop chondrosarcoma via overactivation of YAP signaling.
Li Y; Yang S; Liu Y; Yang S
Cell Death Dis; 2022 Jun; 13(6):570. PubMed ID: 35760773
[TBL] [Abstract][Full Text] [Related]
20. Evolutionary mode and timing of dissemination of high-grade serous carcinomas.
Sveen A; Johannessen B; Klokkerud SM; Kraggerud SM; Meza-Zepeda LA; Bjørnslett M; Bischof K; Myklebost O; Taskén K; Skotheim RI; Dørum A; Davidson B; Lothe RA
JCI Insight; 2024 Jan; 9(3):. PubMed ID: 38175731
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
