These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 31931121)

  • 1. Acidic and alkaline hydrolysis of polysorbates under aqueous conditions: Towards understanding polysorbate degradation in biopharmaceutical formulations.
    Dwivedi M; Buske J; Haemmerling F; Blech M; Garidel P
    Eur J Pharm Sci; 2020 Mar; 144():105211. PubMed ID: 31931121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of Polysorbate Ester Fractions and Implications in Protein Drug Product Stability.
    Tomlinson A; Zarraga IE; Demeule B
    Mol Pharm; 2020 Jul; 17(7):2345-2353. PubMed ID: 32442382
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impact of mono- and poly-ester fractions on polysorbate quantitation using mixed-mode HPLC-CAD/ELSD and the fluorescence micelle assay.
    Lippold S; Koshari SHS; Kopf R; Schuller R; Buckel T; Zarraga IE; Koehn H
    J Pharm Biomed Anal; 2017 Jan; 132():24-34. PubMed ID: 27693757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polysorbate degradation in biotherapeutic formulations: Identification and discussion of current root causes.
    Dwivedi M; Blech M; Presser I; Garidel P
    Int J Pharm; 2018 Dec; 552(1-2):422-436. PubMed ID: 30300706
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation.
    Doshi N; Martin J; Tomlinson A
    Mol Pharm; 2020 Nov; 17(11):4354-4363. PubMed ID: 32941040
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel markers to track oxidative polysorbate degradation in pharmaceutical formulations.
    Dahotre S; Tomlinson A; Lin B; Yadav S
    J Pharm Biomed Anal; 2018 Aug; 157():201-207. PubMed ID: 29803911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions.
    Glücklich N; Carle S; Buske J; Mäder K; Garidel P
    Eur J Pharm Sci; 2021 Nov; 166():105980. PubMed ID: 34419573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Controlled polysorbate 20 hydrolysis - A new approach to assess the impact of polysorbate 20 degradation on biopharmaceutical product quality in shortened time.
    Graf T; Abstiens K; Wedekind F; Elger C; Haindl M; Wurth C; Leiss M
    Eur J Pharm Biopharm; 2020 Jul; 152():318-326. PubMed ID: 32445968
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development and validation of a selective marker-based quantification of polysorbate 20 in biopharmaceutical formulations using UPLC QDa detection.
    Evers DH; Schultz-Fademrecht T; Garidel P; Buske J
    J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Nov; 1157():122287. PubMed ID: 33069954
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization and stability study of polysorbate 20 in therapeutic monoclonal antibody formulation by multidimensional ultrahigh-performance liquid chromatography-charged aerosol detection-mass spectrometry.
    Li Y; Hewitt D; Lentz YK; Ji JA; Zhang TY; Zhang K
    Anal Chem; 2014 May; 86(10):5150-7. PubMed ID: 24749737
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stability of the non-ionic surfactant polysorbate 80 investigated by HPLC-MS and charged aerosol detector.
    Christiansen A; Backensfeld T; Kühn S; Weitschies W
    Pharmazie; 2011 Sep; 66(9):666-71. PubMed ID: 22026121
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigation of excipients impact on polysorbate 80 degradation in biopharmaceutical formulation buffers.
    Bai L; Zhang Y; Zhang C; Lu Y; Li Z; Huang G; Meng B
    J Pharm Biomed Anal; 2023 Sep; 233():115496. PubMed ID: 37285658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80.
    Glücklich N; Dwivedi M; Carle S; Buske J; Mäder K; Garidel P
    Int J Pharm; 2020 Dec; 591():119934. PubMed ID: 33059015
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Considerations for the Use of Polysorbates in Biopharmaceuticals.
    Jones MT; Mahler HC; Yadav S; Bindra D; Corvari V; Fesinmeyer RM; Gupta K; Harmon AM; Hinds KD; Koulov A; Liu W; Maloney K; Wang J; Yeh PY; Singh SK
    Pharm Res; 2018 May; 35(8):148. PubMed ID: 29797101
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Characterization of Polysorbate.
    Zhang S; Xiao H; Li N
    Curr Protoc; 2022 Jul; 2(7):e489. PubMed ID: 35857882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. All-in-one stability indicating polysorbate 20 degradation root-cause analytics via UPLC-QDa.
    Carle S; Evers DH; Hagelskamp E; Garidel P; Buske J
    J Chromatogr B Analyt Technol Biomed Life Sci; 2024 Jan; 1232():123955. PubMed ID: 38128165
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polysorbates versus Hydroxypropyl Beta-Cyclodextrin (HPβCD): Comparative Study on Excipient Stability and Stabilization Benefits on Monoclonal Antibodies.
    Zhang H; Hong S; Tan SSK; Peng T; Goh LYH; Lam KH; Chow KT; Gokhale R
    Molecules; 2022 Oct; 27(19):. PubMed ID: 36235038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Monitoring polysorbate hydrolysis in biopharmaceuticals using a QC-ready free fatty acid quantification method.
    Honemann MN; Wendler J; Graf T; Bathke A; Bell CH
    J Chromatogr B Analyt Technol Biomed Life Sci; 2019 May; 1116():1-8. PubMed ID: 30951966
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways.
    Kerwin BA
    J Pharm Sci; 2008 Aug; 97(8):2924-35. PubMed ID: 17973307
    [TBL] [Abstract][Full Text] [Related]  

  • 20. How enzymatic hydrolysis of polysorbate 20 influences colloidal protein stability.
    Glücklich N; Carle S; Diederichs T; Buske J; Mäder K; Garidel P
    Eur J Pharm Sci; 2023 Dec; 191():106597. PubMed ID: 37770006
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.