BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 31938140)

  • 1. Hypoxia-inducible factor (HIF)-1alpha knockout accelerates intervertebral disc degeneration in mice.
    Meng X; Zhuang L; Wang J; Liu Z; Wang Y; Xiao D; Zhang X
    Int J Clin Exp Pathol; 2018; 11(2):548-557. PubMed ID: 31938140
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SHH-dependent knockout of HIF-1 alpha accelerates the degenerative process in mouse intervertebral disc.
    Wu WJ; Zhang XK; Zheng XF; Yang YH; Jiang SD; Jiang LS
    Int J Immunopathol Pharmacol; 2013; 26(3):601-9. PubMed ID: 24067457
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of Hypoxia-Inducible Factor-1α Signaling Pathway Has the Protective Effect of Intervertebral Disc Degeneration.
    Kim JW; An HJ; Yeo H; Jeong Y; Lee H; Lee J; Nam K; Lee J; Shin DE; Lee S
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768786
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.
    Merceron C; Mangiavini L; Robling A; Wilson TL; Giaccia AJ; Shapiro IM; Schipani E; Risbud MV
    PLoS One; 2014; 9(10):e110768. PubMed ID: 25338007
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regeneration in Spinal Disease: Therapeutic Role of Hypoxia-Inducible Factor-1 Alpha in Regeneration of Degenerative Intervertebral Disc.
    Kim JW; Jeon N; Shin DE; Lee SY; Kim M; Han DH; Shin JY; Lee S
    Int J Mol Sci; 2021 May; 22(10):. PubMed ID: 34067899
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia-inducible factor-lα mediates aggrecan and collagen Π expression via NOTCH1 signaling in nucleus pulposus cells during intervertebral disc degeneration.
    Liu Z; Li C; Meng X; Bai Y; Qi J; Wang J; Zhou Q; Zhang W; Zhang X
    Biochem Biophys Res Commun; 2017 Jul; 488(3):554-561. PubMed ID: 28526405
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc.
    Richardson SM; Knowles R; Tyler J; Mobasheri A; Hoyland JA
    Histochem Cell Biol; 2008 Apr; 129(4):503-11. PubMed ID: 18172662
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
    Yang W; Jia C; Liu L; Fu Y; Wu Y; Liu Z; Yu R; Ma X; Gong A; Liu F; Xia Y; Hou Y; Li Y; Zhang L
    Inflammation; 2023 Feb; 46(1):270-284. PubMed ID: 36064808
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conditional Deletion of HIF-2α in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age-Dependent Structural Changes in Intervertebral Disc.
    Johnston SN; Madhu V; Shapiro IM; Risbud MV
    J Bone Miner Res; 2022 Dec; 37(12):2512-2530. PubMed ID: 36117450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.
    Tran CM; Fujita N; Huang BL; Ong JR; Lyons KM; Shapiro IM; Risbud MV
    J Biol Chem; 2013 May; 288(18):12654-66. PubMed ID: 23530034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1α signaling in nucleus pulposus cells.
    Pan H; Strickland A; Madhu V; Johnson ZI; Chand SN; Brody JR; Fertala A; Zheng Z; Shapiro IM; Risbud MV
    Matrix Biol; 2019 Apr; 77():23-40. PubMed ID: 30092282
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential phenotypic behaviors of human degenerative nucleus pulposus cells under normoxic and hypoxic conditions: influence of oxygen concentration during isolation, expansion, and cultivation.
    Yang SH; Hu MH; Sun YH; Lin FH
    Spine J; 2013 Nov; 13(11):1590-6. PubMed ID: 23800820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanical destabilization induced by controlled annular incision of the intervertebral disc dysregulates metalloproteinase expression and induces disc degeneration.
    Melrose J; Shu C; Young C; Ho R; Smith MM; Young AA; Smith SS; Gooden B; Dart A; Podadera J; Appleyard RC; Little CB
    Spine (Phila Pa 1976); 2012 Jan; 37(1):18-25. PubMed ID: 22179320
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells.
    Johnson ZI; Gogate SS; Day R; Binch A; Markova DZ; Chiverton N; Cole A; Conner M; Shapiro IM; Le Maitre CL; Risbud MV
    Oncotarget; 2015 May; 6(14):11945-58. PubMed ID: 25844601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Effect of "nape seven needles" on expression of hypoxia inducible factor-1α and Notch1 in cervical intervertebral disc degeneration rats].
    Ding FF; Lu Y
    Zhen Ci Yan Jiu; 2022 Oct; 47(10):872-7. PubMed ID: 36301163
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF-1α-BNIP3 Axis.
    Madhu V; Boneski PK; Silagi E; Qiu Y; Kurland I; Guntur AR; Shapiro IM; Risbud MV
    J Bone Miner Res; 2020 Aug; 35(8):1504-1524. PubMed ID: 32251541
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of compositional and structural changes in the nucleus pulposus of patients with cervical disc herniation by Raman spectroscopy.
    Wang Z; Xue T; Zhang T; Wang X; Zhang H; Gao Z; Zhou Q; Gao E; Zhang T; Li Z
    Front Endocrinol (Lausanne); 2022; 13():1015198. PubMed ID: 36277712
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia and Hypoxia-Inducible Factor-1α Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion.
    Novais EJ; Choi H; Madhu V; Suyama K; Anjo SI; Manadas B; Shapiro IM; Salgado AJ; Risbud MV
    Am J Pathol; 2021 Mar; 191(3):487-502. PubMed ID: 33307037
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain.
    Xiong Z; Ding J; Zhou J; Yao S; Zheng J; Guo X
    BMC Musculoskelet Disord; 2020 Jul; 21(1):500. PubMed ID: 32723315
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hypoxia differentially regulates human nucleus pulposus and annulus fibrosus cell extracellular matrix production in 3D scaffolds.
    Feng G; Li L; Liu H; Song Y; Huang F; Tu C; Shen B; Gong Q; Li T; Liu L; Zeng J; Kong Q; Yi M; Gupte M; Ma PX; Pei F
    Osteoarthritis Cartilage; 2013 Apr; 21(4):582-8. PubMed ID: 23313531
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.