These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
76 related articles for article (PubMed ID: 31938452)
1. Novel Methyl-aza-quinazolines as Inhibitors of the RAS-SOS Interaction. Rosse G ACS Med Chem Lett; 2020 Jan; 11(1):2-3. PubMed ID: 31938452 [No Abstract] [Full Text] [Related]
2. An orthosteric inhibitor of the RAS-SOS interaction. Nickerson S; Joy ST; Arora PS; Bar-Sagi D Enzymes; 2013; 34 Pt. B():25-39. PubMed ID: 25034099 [TBL] [Abstract][Full Text] [Related]
3. Structural analysis of autoinhibition in the Ras activator Son of sevenless. Sondermann H; Soisson SM; Boykevisch S; Yang SS; Bar-Sagi D; Kuriyan J Cell; 2004 Oct; 119(3):393-405. PubMed ID: 15507210 [TBL] [Abstract][Full Text] [Related]
4. Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains. Nakamura Y; Hibino K; Yanagida T; Sako Y Biophys Physicobiol; 2016; 13():1-11. PubMed ID: 27924253 [TBL] [Abstract][Full Text] [Related]
5. Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation. Winter JJ; Anderson M; Blades K; Brassington C; Breeze AL; Chresta C; Embrey K; Fairley G; Faulder P; Finlay MR; Kettle JG; Nowak T; Overman R; Patel SJ; Perkins P; Spadola L; Tart J; Tucker JA; Wrigley G J Med Chem; 2015 Mar; 58(5):2265-74. PubMed ID: 25695162 [TBL] [Abstract][Full Text] [Related]
6. Signal transduction in T lymphocytes using a conditional allele of Sos. Holsinger LJ; Spencer DM; Austin DJ; Schreiber SL; Crabtree GR Proc Natl Acad Sci U S A; 1995 Oct; 92(21):9810-4. PubMed ID: 7568223 [TBL] [Abstract][Full Text] [Related]
7. Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos. Buday L; Warne PH; Downward J Oncogene; 1995 Oct; 11(7):1327-31. PubMed ID: 7478553 [TBL] [Abstract][Full Text] [Related]
8. Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Zhao C; Du G; Skowronek K; Frohman MA; Bar-Sagi D Nat Cell Biol; 2007 Jun; 9(6):706-12. PubMed ID: 17486115 [TBL] [Abstract][Full Text] [Related]
9. Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution. Vo U; Vajpai N; Embrey KJ; Golovanov AP Sci Rep; 2016 Jul; 6():29706. PubMed ID: 27412770 [TBL] [Abstract][Full Text] [Related]
10. The structural basis of the activation of Ras by Sos. Boriack-Sjodin PA; Margarit SM; Bar-Sagi D; Kuriyan J Nature; 1998 Jul; 394(6691):337-43. PubMed ID: 9690470 [TBL] [Abstract][Full Text] [Related]
11. Inhibitors of Ras-SOS Interactions. Lu S; Jang H; Zhang J; Nussinov R ChemMedChem; 2016 Apr; 11(8):814-21. PubMed ID: 26630662 [TBL] [Abstract][Full Text] [Related]
12. Comparison of the predicted structures of loops in the ras-SOS protein bound to a single ras-p21 protein with the crystallographically determined structures in SOS bound to two ras-p21 proteins. Smith S; Hyde M; Pincus MR Protein J; 2005 Aug; 24(6):391-8. PubMed ID: 16323045 [TBL] [Abstract][Full Text] [Related]
13. Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Aronheim A; Engelberg D; Li N; al-Alawi N; Schlessinger J; Karin M Cell; 1994 Sep; 78(6):949-61. PubMed ID: 7923364 [TBL] [Abstract][Full Text] [Related]
14. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes. Roose JP; Mollenauer M; Ho M; Kurosaki T; Weiss A Mol Cell Biol; 2007 Apr; 27(7):2732-45. PubMed ID: 17283063 [TBL] [Abstract][Full Text] [Related]
15. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Margarit SM; Sondermann H; Hall BE; Nagar B; Hoelz A; Pirruccello M; Bar-Sagi D; Kuriyan J Cell; 2003 Mar; 112(5):685-95. PubMed ID: 12628188 [TBL] [Abstract][Full Text] [Related]
16. Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos. Nimnual AS; Yatsula BA; Bar-Sagi D Science; 1998 Jan; 279(5350):560-3. PubMed ID: 9438849 [TBL] [Abstract][Full Text] [Related]
17. Insulin-induced dissociation of Sos from Grb2 does not contribute to the down regulation of Ras activation. Corbalan-Garcia S; Degenhardt KR; Bar-Sagi D Oncogene; 1996 Mar; 12(5):1063-8. PubMed ID: 8649797 [TBL] [Abstract][Full Text] [Related]
18. Loop domain peptides from the SOS ras-guanine nucleotide exchange protein, identified from molecular dynamics calculations, strongly inhibit ras signaling. Chie L; Friedman FK; Duncan T; Chen JM; Chung D; Pincus M Protein J; 2004 Apr; 23(3):229-34. PubMed ID: 15200054 [TBL] [Abstract][Full Text] [Related]
19. A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity. Cussac D; Vidal M; Leprince C; Liu WQ; Cornille F; Tiraboschi G; Roques BP; Garbay C FASEB J; 1999 Jan; 13(1):31-8. PubMed ID: 9872927 [TBL] [Abstract][Full Text] [Related]
20. An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. Scita G; Tenca P; Areces LB; Tocchetti A; Frittoli E; Giardina G; Ponzanelli I; Sini P; Innocenti M; Di Fiore PP J Cell Biol; 2001 Sep; 154(5):1031-44. PubMed ID: 11524436 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]