157 related articles for article (PubMed ID: 31939292)
1. Mechanism of Molecular Oxygen Diffusion in a Hypoxia-Sensing Prolyl Hydroxylase Using Multiscale Simulation.
Domene C; Jorgensen C; Schofield CJ
J Am Chem Soc; 2020 Feb; 142(5):2253-2263. PubMed ID: 31939292
[TBL] [Abstract][Full Text] [Related]
2. Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from
Liu T; Abboud MI; Chowdhury R; Tumber A; Hardy AP; Lippl K; Lohans CT; Pires E; Wickens J; McDonough MA; West CM; Schofield CJ
J Biol Chem; 2020 Dec; 295(49):16545-16561. PubMed ID: 32934009
[TBL] [Abstract][Full Text] [Related]
3. Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
McDonough MA; Li V; Flashman E; Chowdhury R; Mohr C; Liénard BM; Zondlo J; Oldham NJ; Clifton IJ; Lewis J; McNeill LA; Kurzeja RJ; Hewitson KS; Yang E; Jordan S; Syed RS; Schofield CJ
Proc Natl Acad Sci U S A; 2006 Jun; 103(26):9814-9. PubMed ID: 16782814
[TBL] [Abstract][Full Text] [Related]
4. Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen.
Tarhonskaya H; Chowdhury R; Leung IK; Loik ND; McCullagh JS; Claridge TD; Schofield CJ; Flashman E
Biochem J; 2014 Nov; 463(3):363-72. PubMed ID: 25120187
[TBL] [Abstract][Full Text] [Related]
5. Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal
Lippl K; Boleininger A; McDonough MA; Abboud MI; Tarhonskaya H; Chowdhury R; Loenarz C; Schofield CJ
Hypoxia (Auckl); 2018; 6():57-71. PubMed ID: 30519597
[TBL] [Abstract][Full Text] [Related]
6. Structural Characterization of Hypoxia Inducible Factor α-Prolyl Hydroxylase Domain 2 Interaction through MD Simulations.
Camagni GF; Minervini G; Tosatto SCE
Int J Mol Sci; 2023 Mar; 24(5):. PubMed ID: 36902141
[TBL] [Abstract][Full Text] [Related]
7. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
Chowdhury R; McDonough MA; Mecinović J; Loenarz C; Flashman E; Hewitson KS; Domene C; Schofield CJ
Structure; 2009 Jul; 17(7):981-9. PubMed ID: 19604478
[TBL] [Abstract][Full Text] [Related]
8. Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change.
Pektas S; Knapp MJ
J Inorg Biochem; 2013 Sep; 126():55-60. PubMed ID: 23787140
[TBL] [Abstract][Full Text] [Related]
9. Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation.
Scotti JS; Leung IK; Ge W; Bentley MA; Paps J; Kramer HB; Lee J; Aik W; Choi H; Paulsen SM; Bowman LA; Loik ND; Horita S; Ho CH; Kershaw NJ; Tang CM; Claridge TD; Preston GM; McDonough MA; Schofield CJ
Proc Natl Acad Sci U S A; 2014 Sep; 111(37):13331-6. PubMed ID: 25197067
[TBL] [Abstract][Full Text] [Related]
10. 2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2.
Abboud MI; McAllister TE; Leung IKH; Chowdhury R; Jorgensen C; Domene C; Mecinović J; Lippl K; Hancock RL; Hopkinson RJ; Kawamura A; Claridge TDW; Schofield CJ
Chem Commun (Camb); 2018 Mar; 54(25):3130-3133. PubMed ID: 29522057
[TBL] [Abstract][Full Text] [Related]
11. Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
Pientka FK; Hu J; Schindler SG; Brix B; Thiel A; Jöhren O; Fandrey J; Berchner-Pfannschmidt U; Depping R
J Cell Sci; 2012 Nov; 125(Pt 21):5168-76. PubMed ID: 22946054
[TBL] [Abstract][Full Text] [Related]
12. Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
Hewitson KS; Schofield CJ; Ratcliffe PJ
Methods Enzymol; 2007; 435():25-42. PubMed ID: 17998047
[TBL] [Abstract][Full Text] [Related]
13. Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases.
Flashman E; Bagg EA; Chowdhury R; Mecinović J; Loenarz C; McDonough MA; Hewitson KS; Schofield CJ
J Biol Chem; 2008 Feb; 283(7):3808-15. PubMed ID: 18063574
[TBL] [Abstract][Full Text] [Related]
14. The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
Barth S; Nesper J; Hasgall PA; Wirthner R; Nytko KJ; Edlich F; Katschinski DM; Stiehl DP; Wenger RH; Camenisch G
Mol Cell Biol; 2007 May; 27(10):3758-68. PubMed ID: 17353276
[TBL] [Abstract][Full Text] [Related]
15. Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
Strowitzki MJ; Cummins EP; Taylor CT
Cells; 2019 Apr; 8(5):. PubMed ID: 31035491
[TBL] [Abstract][Full Text] [Related]
16. Molecular characterization and mRNA expression of HIF-prolyl hydroxylase-2 (phd2) in hypoxia-sensing pathways from Megalobrama amblycephala.
Wang H; Huang C; Chen N; Zhu K; Chen B; Wang W; Wang H
Comp Biochem Physiol B Biochem Mol Biol; 2015 Aug; 186():28-35. PubMed ID: 25868626
[TBL] [Abstract][Full Text] [Related]
17. Biochemistry of the hypoxia-inducible factor hydroxylases.
Fiorini G; Schofield CJ
Curr Opin Chem Biol; 2024 Apr; 79():102428. PubMed ID: 38330792
[TBL] [Abstract][Full Text] [Related]
18. Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.
Berchner-Pfannschmidt U; Yamac H; Trinidad B; Fandrey J
J Biol Chem; 2007 Jan; 282(3):1788-96. PubMed ID: 17060326
[TBL] [Abstract][Full Text] [Related]
19. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
Mole DR; Maxwell PH; Pugh CW; Ratcliffe PJ
IUBMB Life; 2001 Jul; 52(1-2):43-7. PubMed ID: 11795592
[TBL] [Abstract][Full Text] [Related]
20. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]