BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 31941999)

  • 1. Combinatorial allosteric modulation of agonist response in a self-interacting G-protein coupled receptor.
    Patrone M; Cammarota E; Berno V; Tornaghi P; Mazza D; Degano M
    Commun Biol; 2020 Jan; 3(1):27. PubMed ID: 31941999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics.
    Xiao K; Sun J
    Cell Signal; 2018 Jan; 41():56-64. PubMed ID: 28939107
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Class B1 GPCR activation by an intracellular agonist.
    Kobayashi K; Kawakami K; Kusakizako T; Tomita A; Nishimura M; Sawada K; Okamoto HH; Hiratsuka S; Nakamura G; Kuwabara R; Noda H; Muramatsu H; Shimizu M; Taguchi T; Inoue A; Murata T; Nureki O
    Nature; 2023 Jun; 618(7967):1085-1093. PubMed ID: 37286611
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression.
    Paradis JS; Ly S; Blondel-Tepaz É; Galan JA; Beautrait A; Scott MG; Enslen H; Marullo S; Roux PP; Bouvier M
    Proc Natl Acad Sci U S A; 2015 Sep; 112(37):E5160-8. PubMed ID: 26324936
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Insights into Phosphorylation-Induced Allosteric Conformational Changes in a β
    Madhu MK; Debroy A; Murarka RK
    J Phys Chem B; 2022 Mar; 126(9):1917-1932. PubMed ID: 35196859
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric inhibition of g-protein coupled receptor oligomerization: strategies and challenges for drug development.
    Hurevich M; Talhami A; Shalev DE; Gilon C
    Curr Top Med Chem; 2014; 14(15):1842-63. PubMed ID: 25175995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity.
    Sanchez-Soto M; Verma RK; Willette BKA; Gonye EC; Moore AM; Moritz AE; Boateng CA; Yano H; Free RB; Shi L; Sibley DR
    Sci Signal; 2020 Feb; 13(617):. PubMed ID: 32019899
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein.
    Vilardaga JP; Frank M; Krasel C; Dees C; Nissenson RA; Lohse MJ
    J Biol Chem; 2001 Sep; 276(36):33435-43. PubMed ID: 11387315
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arrestin interactions with G protein-coupled receptors.
    Lohse MJ; Hoffmann C
    Handb Exp Pharmacol; 2014; 219():15-56. PubMed ID: 24292823
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors.
    Marion S; Oakley RH; Kim KM; Caron MG; Barak LS
    J Biol Chem; 2006 Feb; 281(5):2932-8. PubMed ID: 16319069
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR.
    Miller WE; Houtz DA; Nelson CD; Kolattukudy PE; Lefkowitz RJ
    J Biol Chem; 2003 Jun; 278(24):21663-71. PubMed ID: 12668664
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric communication regulates ligand-specific GPCR activity.
    Ma N; Nivedha AK; Vaidehi N
    FEBS J; 2021 Apr; 288(8):2502-2512. PubMed ID: 33738925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Molecular Basis of G Protein-Coupled Receptor Activation.
    Weis WI; Kobilka BK
    Annu Rev Biochem; 2018 Jun; 87():897-919. PubMed ID: 29925258
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation.
    Estall JL; Koehler JA; Yusta B; Drucker DJ
    J Biol Chem; 2005 Jun; 280(23):22124-34. PubMed ID: 15817468
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heterologous phosphorylation-induced formation of a stability lock permits regulation of inactive receptors by β-arrestins.
    Tóth AD; Prokop S; Gyombolai P; Várnai P; Balla A; Gurevich VV; Hunyady L; Turu G
    J Biol Chem; 2018 Jan; 293(3):876-892. PubMed ID: 29146594
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biased Allostery.
    Edelstein SJ; Changeux JP
    Biophys J; 2016 Sep; 111(5):902-8. PubMed ID: 27602718
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural Characterization of Receptor-Receptor Interactions in the Allosteric Modulation of G Protein-Coupled Receptor (GPCR) Dimers.
    Lazim R; Suh D; Lee JW; Vu TNL; Yoon S; Choi S
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33810175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel Structural Insights into GPCR-β-Arrestin Interaction and Signaling.
    Ranjan R; Dwivedi H; Baidya M; Kumar M; Shukla AK
    Trends Cell Biol; 2017 Nov; 27(11):851-862. PubMed ID: 28651823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Emerging opportunities for allosteric modulation of G-protein coupled receptors.
    Wang CI; Lewis RJ
    Biochem Pharmacol; 2013 Jan; 85(2):153-62. PubMed ID: 22975406
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and dynamics of GPCR signaling complexes.
    Hilger D; Masureel M; Kobilka BK
    Nat Struct Mol Biol; 2018 Jan; 25(1):4-12. PubMed ID: 29323277
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.