These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 31943253)

  • 21. Cyclodextrin mediates rapid changes in lipid balance in Npc1-/- mice without carrying cholesterol through the bloodstream.
    Taylor AM; Liu B; Mari Y; Liu B; Repa JJ
    J Lipid Res; 2012 Nov; 53(11):2331-42. PubMed ID: 22892156
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Intracerebroventricular 2-hydroxypropyl-γ-cyclodextrin alleviates hepatic manifestations without distributing to the liver in a murine model of Niemann-Pick disease type C.
    Yamada Y; Ishitsuka Y; Fukaura-Nishizawa M; Kawata T; Ishii A; Shirakawa A; Sakai T; Tanaka M; Kondo Y; Takeo T; Nakagata N; Motoyama K; Higashi T; Arima H; Seki T; Kurauchi Y; Katsuki H; Higaki K; Ikeda R; Matsuo M; Era T; Irie T
    Life Sci; 2024 Aug; 350():122776. PubMed ID: 38852794
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann-Pick Disease Type C Model Mice.
    Fukaura M; Ishitsuka Y; Shirakawa S; Ushihama N; Yamada Y; Kondo Y; Takeo T; Nakagata N; Motoyama K; Higashi T; Arima H; Kurauchi Y; Seki T; Katsuki H; Higaki K; Matsuo M; Irie T
    Int J Mol Sci; 2021 Jan; 22(1):. PubMed ID: 33466390
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Intrathecal 2-hydroxypropyl-beta-cyclodextrin in a single patient with Niemann-Pick C1.
    Maarup TJ; Chen AH; Porter FD; Farhat NY; Ory DS; Sidhu R; Jiang X; Dickson PI
    Mol Genet Metab; 2015; 116(1-2):75-9. PubMed ID: 26189084
    [TBL] [Abstract][Full Text] [Related]  

  • 25. HPGCD outperforms HPBCD as a potential treatment for Niemann-Pick disease type C during disease modeling with iPS cells.
    Soga M; Ishitsuka Y; Hamasaki M; Yoneda K; Furuya H; Matsuo M; Ihn H; Fusaki N; Nakamura K; Nakagata N; Endo F; Irie T; Era T
    Stem Cells; 2015 Apr; 33(4):1075-88. PubMed ID: 25522247
    [TBL] [Abstract][Full Text] [Related]  

  • 26. [Inclusion Solves Insolubility -Translational Research Cycle from Bedside to Bench and Bench to Bedside for Drug Development Targeting Niemann-Pick Disease Type C].
    Irie T
    Yakugaku Zasshi; 2022; 142(4):389-400. PubMed ID: 35370195
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis of 2-hydroxypropyl-β-cyclodextrin/pluronic-based polyrotaxanes via heterogeneous reaction as potential Niemann-Pick type C therapeutics.
    Mondjinou YA; McCauliff LA; Kulkarni A; Paul L; Hyun SH; Zhang Z; Wu Z; Wirth M; Storch J; Thompson DH
    Biomacromolecules; 2013 Dec; 14(12):4189-97. PubMed ID: 24180231
    [TBL] [Abstract][Full Text] [Related]  

  • 28. [Intracellularly Degradable Polyrotaxanes for Therapeutic Applications].
    Tamura A
    Yakugaku Zasshi; 2019; 139(2):143-155. PubMed ID: 30713223
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype.
    Argüello G; Balboa E; Tapia PJ; Castro J; Yañez MJ; Mattar P; Pulgar R; Zanlungo S
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33921734
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Function of the Niemann-Pick type C proteins and their bypass by cyclodextrin.
    Vance JE; Peake KB
    Curr Opin Lipidol; 2011 Jun; 22(3):204-9. PubMed ID: 21412152
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Pluronic based β-cyclodextrin polyrotaxanes for treatment of Niemann-Pick Type C disease.
    Collins CJ; Loren BP; Alam MS; Mondjinou Y; Skulsky JL; Chaplain CR; Haldar K; Thompson DH
    Sci Rep; 2017 Apr; 7():46737. PubMed ID: 28452365
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss.
    Yamada Y; Miwa T; Nakashima M; Shirakawa A; Ishii A; Namba N; Kondo Y; Takeo T; Nakagata N; Motoyama K; Higashi T; Arima H; Kurauchi Y; Seki T; Katsuki H; Okada Y; Ichikawa A; Higaki K; Hayashi K; Minami K; Yoshikawa N; Ikeda R; Ishikawa Y; Kajii T; Tachii K; Takeda H; Orita Y; Matsuo M; Irie T; Ishitsuka Y
    Biomed Pharmacother; 2022 Nov; 155():113698. PubMed ID: 36116252
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann-Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease.
    Tanaka Y; Yamada Y; Ishitsuka Y; Matsuo M; Shiraishi K; Wada K; Uchio Y; Kondo Y; Takeo T; Nakagata N; Higashi T; Motoyama K; Arima H; Mochinaga S; Higaki K; Ohno K; Irie T
    Biol Pharm Bull; 2015; 38(6):844-51. PubMed ID: 26027824
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Investigating the Mechanism of Cyclodextrins in the Treatment of Niemann-Pick Disease Type C Using Crosslinked 2-Hydroxypropyl-β-cyclodextrin.
    Carradori D; Chen H; Werner B; Shah AS; Leonardi C; Usuelli M; Mezzenga R; Platt F; Leroux JC
    Small; 2020 Nov; 16(46):e2004735. PubMed ID: 33079457
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK.
    Dai S; Dulcey AE; Hu X; Wassif CA; Porter FD; Austin CP; Ory DS; Marugan J; Zheng W
    Autophagy; 2017 Aug; 13(8):1435-1451. PubMed ID: 28613987
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.
    Contreras PS; Gonzalez-Zuñiga M; González-Hódar L; Yáñez MJ; Dulcey A; Marugan J; Seto E; Alvarez AR; Zanlungo S
    Biochim Biophys Acta; 2016 Feb; 1859(2):269-79. PubMed ID: 26603102
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Regulation of the cell swelling-activated chloride conductance by cholesterol-rich membrane domains.
    Lim CH; Schoonderwoerd K; Kleijer WJ; de Jonge HR; Tilly BC
    Acta Physiol (Oxf); 2006; 187(1-2):295-303. PubMed ID: 16734766
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Lactose-Appended Hydroxypropyl-β-Cyclodextrin Lowers Cholesterol Accumulation and Alleviates Motor Dysfunction in Niemann-Pick Type C Disease Model Mice.
    Nishida T; Yokoyama R; Kubohira Y; Maeda Y; Takeo T; Nakagata N; Takagi H; Ishikura K; Yanagihara K; Misumi S; Kishimoto N; Ishitsuka Y; Kondo Y; Irie T; Soga M; Era T; Onodera R; Higashi T; Motoyama K
    ACS Appl Bio Mater; 2022 May; 5(5):2377-2388. PubMed ID: 35506864
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann-Pick disease type C treatment.
    Yamada Y; Fukaura-Nishizawa M; Nishiyama A; Ishii A; Kawata T; Shirakawa A; Tanaka M; Kondo Y; Takeo T; Nakagata N; Miwa T; Takeda H; Orita Y; Motoyama K; Higashi T; Arima H; Seki T; Kurauchi Y; Katsuki H; Higaki K; Minami K; Yoshikawa N; Ikeda R; Matsuo M; Irie T; Ishitsuka Y
    Clin Transl Med; 2023 Aug; 13(8):e1350. PubMed ID: 37620691
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effects of cyclodextrin in two patients with Niemann-Pick Type C disease.
    Matsuo M; Togawa M; Hirabaru K; Mochinaga S; Narita A; Adachi M; Egashira M; Irie T; Ohno K
    Mol Genet Metab; 2013 Jan; 108(1):76-81. PubMed ID: 23218948
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.