223 related articles for article (PubMed ID: 31947743)
1. Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity.
Northrop A; Vangala JR; Feygin A; Radhakrishnan SK
Int J Mol Sci; 2020 Jan; 21(1):. PubMed ID: 31947743
[TBL] [Abstract][Full Text] [Related]
2. The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.
Koizumi S; Irie T; Hirayama S; Sakurai Y; Yashiroda H; Naguro I; Ichijo H; Hamazaki J; Murata S
Elife; 2016 Aug; 5():. PubMed ID: 27528193
[TBL] [Abstract][Full Text] [Related]
3. p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition.
Radhakrishnan SK; den Besten W; Deshaies RJ
Elife; 2014; 3():e01856. PubMed ID: 24448410
[TBL] [Abstract][Full Text] [Related]
4. The aspartyl protease DDI2 drives adaptation to proteasome inhibition in multiple myeloma.
Op M; Ribeiro ST; Chavarria C; De Gassart A; Zaffalon L; Martinon F
Cell Death Dis; 2022 May; 13(5):475. PubMed ID: 35589686
[TBL] [Abstract][Full Text] [Related]
5. Nrf1 can be processed and activated in a proteasome-independent manner.
Vangala JR; Sotzny F; Krüger E; Deshaies RJ; Radhakrishnan SK
Curr Biol; 2016 Sep; 26(18):R834-R835. PubMed ID: 27676297
[TBL] [Abstract][Full Text] [Related]
6. Multiple myeloma cells depend on the DDI2/NRF1-mediated proteasome stress response for survival.
Chen T; Ho M; Briere J; Moscvin M; Czarnecki PG; Anderson KC; Blackwell TK; Bianchi G
Blood Adv; 2022 Jan; 6(2):429-440. PubMed ID: 34649278
[TBL] [Abstract][Full Text] [Related]
7. Nelfinavir inhibits human DDI2 and potentiates cytotoxicity of proteasome inhibitors.
Gu Y; Wang X; Wang Y; Wang Y; Li J; Yu FX
Cell Signal; 2020 Nov; 75():109775. PubMed ID: 32916277
[TBL] [Abstract][Full Text] [Related]
8. DDI2 Is a Ubiquitin-Directed Endoprotease Responsible for Cleavage of Transcription Factor NRF1.
Dirac-Svejstrup AB; Walker J; Faull P; Encheva V; Akimov V; Puglia M; Perkins D; Kümper S; Hunjan SS; Blagoev B; Snijders AP; Powell DJ; Svejstrup JQ
Mol Cell; 2020 Jul; 79(2):332-341.e7. PubMed ID: 32521225
[TBL] [Abstract][Full Text] [Related]
9. ER-Resident Transcription Factor Nrf1 Regulates Proteasome Expression and Beyond.
Hamazaki J; Murata S
Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32456207
[TBL] [Abstract][Full Text] [Related]
10. UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage.
Hu X; Zou R; Zhang Z; Ji J; Li J; Huo XY; Liu D; Ge MX; Cui MK; Wu MZ; Li ZP; Wang Q; Zhang X; Zhang ZR
Biochim Biophys Acta Gene Regul Mech; 2023 Jun; 1866(2):194937. PubMed ID: 37084817
[TBL] [Abstract][Full Text] [Related]
11. Proteasome-mediated processing of Nrf1 is essential for coordinate induction of all proteasome subunits and p97.
Sha Z; Goldberg AL
Curr Biol; 2014 Jul; 24(14):1573-1583. PubMed ID: 24998528
[TBL] [Abstract][Full Text] [Related]
12. TCF11/Nrf1-Mediated Induction of Proteasome Expression Prevents Cytotoxicity by Rotenone.
Sotzny F; Schormann E; Kühlewindt I; Koch A; Brehm A; Goldbach-Mansky R; Gilling KE; Krüger E
Antioxid Redox Signal; 2016 Dec; 25(16):870-885. PubMed ID: 27345029
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of calpain-1 stabilizes TCF11/Nrf1 but does not affect its activation in response to proteasome inhibition.
Nowak K; Taubert RM; Haberecht S; Venz S; Krüger E
Biosci Rep; 2018 Oct; 38(5):. PubMed ID: 30177525
[TBL] [Abstract][Full Text] [Related]
14. Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma.
Fassmannová D; Sedlák F; Sedláček J; Špička I; Grantz Šašková K
Cancers (Basel); 2020 Apr; 12(5):. PubMed ID: 32344880
[TBL] [Abstract][Full Text] [Related]
15. Transcriptional regulation of the 26S proteasome by Nrf1.
Koizumi S; Hamazaki J; Murata S
Proc Jpn Acad Ser B Phys Biol Sci; 2018; 94(8):325-336. PubMed ID: 30305478
[TBL] [Abstract][Full Text] [Related]
16. Regulation of NRF1, a master transcription factor of proteasome genes: implications for cancer and neurodegeneration.
Northrop A; Byers HA; Radhakrishnan SK
Mol Biol Cell; 2020 Sep; 31(20):2158-2163. PubMed ID: 32924844
[TBL] [Abstract][Full Text] [Related]
17. Reply to Vangala et al.: Complete inhibition of the proteasome reduces new proteasome production by causing Nrf1 aggregation.
Sha Z; Goldberg AL
Curr Biol; 2016 Sep; 26(18):R836-R837. PubMed ID: 27676298
[TBL] [Abstract][Full Text] [Related]
18. Early recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2.
Ibtisam I; Kisselev AF
Elife; 2024 Apr; 12():. PubMed ID: 38619391
[TBL] [Abstract][Full Text] [Related]
19. Regulation and Functions of the ER-Associated Nrf1 Transcription Factor.
Ruvkun G; Lehrbach N
Cold Spring Harb Perspect Biol; 2023 Jan; 15(1):. PubMed ID: 35940907
[TBL] [Abstract][Full Text] [Related]
20. ER-trafficking triggers NRF1 ubiquitination to promote its proteolytic activation.
Chavarria C; Zaffalon L; Ribeiro ST; Op M; Quadroni M; Iatrou MS; Chapuis C; Martinon F
iScience; 2023 Oct; 26(10):107777. PubMed ID: 37720101
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
