BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 31948845)

  • 21. Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor.
    Nyimanu D; Kuc RE; Williams TL; Bednarek M; Ambery P; Jermutus L; Maguire JJ; Davenport AP
    Peptides; 2019 Nov; 121():170139. PubMed ID: 31472173
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Identifying structural determinants of potency for analogs of apelin-13: integration of C-terminal truncation with structure-activity.
    Zhang Y; Maitra R; Harris DL; Dhungana S; Snyder R; Runyon SP
    Bioorg Med Chem; 2014 Jun; 22(11):2992-7. PubMed ID: 24755525
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptor.
    Kim HY; Jadhav VB; Jeong DY; Park WK; Song JH; Lee S; Cho H
    Arch Pharm Res; 2015 Jun; 38(6):1019-32. PubMed ID: 25599616
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of 6-hydroxy-5-phenyl sulfonylpyrimidin-4(1H)-one APJ receptor agonists.
    Tora G; Jiang J; Bostwick JS; Gargalovic PS; Onorato JM; Luk CE; Generaux C; Xu C; Galella MA; Wang T; He Y; Wexler RR; Finlay HJ
    Bioorg Med Chem Lett; 2021 Oct; 50():128325. PubMed ID: 34403724
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Apelin, APJ, and ELABELA: Role in Placental Function, Pregnancy, and Foetal Development-An Overview.
    Dawid M; Mlyczyńska E; Jurek M; Respekta N; Pich K; Kurowska P; Gieras W; Milewicz T; Kotula-Balak M; Rak A
    Cells; 2021 Dec; 11(1):. PubMed ID: 35011661
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Comparative Study of Elabela and Apelin on Apelin Receptor Activation Through β-Arrestin Recruitment.
    Zhang H; Chen J; Shi M; Xu F; Zhang X; Gong DW
    Mol Biotechnol; 2023 Mar; 65(3):394-400. PubMed ID: 35960440
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation.
    Reed AB; Lanman BA; Holder JR; Yang BH; Ma J; Humphreys SC; Wang Z; Chan JCY; Miranda LP; Swaminath G; Allen JG
    Bioorg Med Chem Lett; 2020 Nov; 30(21):127499. PubMed ID: 32858124
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The apelinergic-axis in human preeclamptic pregnancies: A systematic review.
    Georgiadou D; Afink GB; van Dijk M
    Pregnancy Hypertens; 2019 Jul; 17():148-157. PubMed ID: 31487633
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Design and preparation of N-linked hydroxypyridine-based APJ agonists.
    Richter JM; Alex Bates J; Gargalovic P; Onorato JM; Generaux C; Wang T; Gordon DA; Wexler RR; Finlay HJ
    Bioorg Med Chem Lett; 2022 Oct; 73():128882. PubMed ID: 35817293
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Identification of a Hydroxypyrimidinone Compound (
    Meng W; Pi Z; Brigance R; Rossi KA; Schumacher WA; Bostwick JS; Gargalovic PS; Onorato JM; Luk CE; Generaux CN; Wang T; Wexler RR; Finlay HJ
    J Med Chem; 2021 Dec; 64(24):18102-18113. PubMed ID: 34855405
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Elabela-apelin receptor signaling pathway is functional in mammalian systems.
    Wang Z; Yu D; Wang M; Wang Q; Kouznetsova J; Yang R; Qian K; Wu W; Shuldiner A; Sztalryd C; Zou M; Zheng W; Gong DW
    Sci Rep; 2015 Feb; 5():8170. PubMed ID: 25639753
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment.
    Besserer-Offroy É; Bérubé P; Côté J; Murza A; Longpré JM; Dumaine R; Lesur O; Auger-Messier M; Leduc R; Marsault É; Sarret P
    Pharmacol Res; 2018 May; 131():7-16. PubMed ID: 29530600
    [TBL] [Abstract][Full Text] [Related]  

  • 33. An Expedient Synthesis of CMF-019: (S)-5-Methyl-3-{1-(pentan-3-yl)-2- (thiophen-2-ylmethyl)-1H-benzo[d]imidazole-5-carboxamido}hexanoic Acid, a Potent Apelin Receptor (APJ) Agonist.
    Trifonov L; Afri M; Palczewski K; Korshin EE; Gruzman A
    Med Chem; 2018; 14(7):688-694. PubMed ID: 29651942
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Simultaneous Ligand and Receptor Tracking through NMR Spectroscopy Enabled by Distinct
    Simmons JR; Murza A; Lumsden MD; Kenward C; Marsault É; Rainey JK
    Int J Mol Sci; 2019 Jul; 20(15):. PubMed ID: 31357423
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The apelin/APJ system as a therapeutic target in metabolic diseases.
    Castan-Laurell I; Masri B; Valet P
    Expert Opin Ther Targets; 2019 Mar; 23(3):215-225. PubMed ID: 30570369
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.
    Deiana V; Gómez-Cañas M; Pazos MR; Fernández-Ruiz J; Asproni B; Cichero E; Fossa P; Muñoz E; Deligia F; Murineddu G; García-Arencibia M; Pinna GA
    Eur J Med Chem; 2016 Apr; 112():66-80. PubMed ID: 26890113
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cardiovascular response to small-molecule APJ activation.
    Ason B; Chen Y; Guo Q; Hoagland KM; Chui RW; Fielden M; Sutherland W; Chen R; Zhang Y; Mihardja S; Ma X; Li X; Sun Y; Liu D; Nguyen K; Wang J; Li N; Rajamani S; Qu Y; Gao B; Boden A; Chintalgattu V; Turk JR; Chan J; Hu LA; Dransfield P; Houze J; Wong J; Ma J; Pattaropong V; Véniant MM; Vargas HM; Swaminath G; Khakoo AY
    JCI Insight; 2020 Apr; 5(8):. PubMed ID: 32208384
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate.
    Johnson JA; Kim SH; Jiang J; Phillips M; Schumacher WA; Bostwick JS; Gargalovic PS; Onorato JM; Luk CE; Generaux C; He Y; Chen XQ; Xu C; Galella MA; Wang T; Gordon DA; Wexler RR; Finlay HJ
    J Med Chem; 2021 Mar; 64(6):3086-3099. PubMed ID: 33689340
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Apelin/APJ system: A potential therapeutic target for endothelial dysfunction-related diseases.
    Cheng J; Luo X; Huang Z; Chen L
    J Cell Physiol; 2019 Aug; 234(8):12149-12160. PubMed ID: 30585633
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Apelin binding to human APJ receptor leads to biased signaling.
    Kumar P; Ashokan A; Aradhyam GK
    Biochim Biophys Acta; 2016 Dec; 1864(12):1748-1756. PubMed ID: 27671350
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.