These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 31951182)

  • 21. 2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma.
    Viswanathan A; Kute D; Musa A; Konda Mani S; Sipilä V; Emmert-Streib F; Zubkov FI; Gurbanov AV; Yli-Harja O; Kandhavelu M
    Eur J Med Chem; 2019 Mar; 166():291-303. PubMed ID: 30731398
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Carbazole Derivatives as Kinase-Targeting Inhibitors for Cancer Treatment.
    Ceramella J; Iacopetta D; Barbarossa A; Caruso A; Grande F; Bonomo MG; Mariconda A; Longo P; Carmela S; Sinicropi MS
    Mini Rev Med Chem; 2020; 20(6):444-465. PubMed ID: 31951166
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis.
    Arun A; Patel OPS; Saini D; Yadav PP; Konwar R
    Biomed Pharmacother; 2017 Sep; 93():510-521. PubMed ID: 28675857
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and Biological Evaluations of Monocarbonyl Curcumin Inspired Pyrazole Analogues as Potential Anti-Colon Cancer Agent.
    Min Z; Zhu Y; Hong X; Yu Z; Ye M; Yuan Q; Hu X
    Drug Des Devel Ther; 2020; 14():2517-2534. PubMed ID: 32636614
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis.
    Maher M; Kassab AE; Zaher AF; Mahmoud Z
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):532-546. PubMed ID: 30688116
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Computer-aided drug design and inhibitive effect of a novel nitrogenous heterocyclic compound and its mechanism on glioma U251 cells and breast cancer MCF-7 cells.
    Qian L; Zhu Y
    Drug Des Devel Ther; 2018; 12():1931-1939. PubMed ID: 29983547
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.
    Truffaux N; Philippe C; Paulsson J; Andreiuolo F; Guerrini-Rousseau L; Cornilleau G; Le Dret L; Richon C; Lacroix L; Puget S; Geoerger B; Vassal G; Östman A; Grill J
    Neuro Oncol; 2015 Jul; 17(7):953-64. PubMed ID: 25534822
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 3'-(4-(Benzyloxy)phenyl)-1'-phenyl-5-(heteroaryl/aryl)-3,4-dihydro-1'H,2H-[3,4'-bipyrazole]-2-carboxamides as EGFR kinase inhibitors: Synthesis, anticancer evaluation, and molecular docking studies.
    Nawaz F; Alam O; Perwez A; Rizvi MA; Naim MJ; Siddiqui N; Pottoo FH; Jha M
    Arch Pharm (Weinheim); 2020 Apr; 353(4):e1900262. PubMed ID: 32003485
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Design, synthesis, DNA binding studies and evaluation of anticancer potential of novel substituted biscarbazole derivatives against human glioma U87 MG cell line.
    Kumar N; Lal N; Nemaysh V; Luthra PM
    Bioorg Chem; 2020 Jul; 100():103911. PubMed ID: 32502918
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Identification of a novel recepteur d'origine nantais/c-met small-molecule kinase inhibitor with antitumor activity in vivo.
    Zhang Y; Kaplan-Lefko PJ; Rex K; Yang Y; Moriguchi J; Osgood T; Mattson B; Coxon A; Reese M; Kim TS; Lin J; Chen A; Burgess TL; Dussault I
    Cancer Res; 2008 Aug; 68(16):6680-7. PubMed ID: 18701492
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer.
    Rajagopalan P; Alahmari KA; Elbessoumy AA; Balasubramaniam M; Suresh R; Shariff ME; Chandramoorthy HC
    Cancer Chemother Pharmacol; 2016 Feb; 77(2):393-404. PubMed ID: 26781309
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway.
    Kapral M; Wawszczyk J; Jesse K; Paul-Samojedny M; Kuśmierz D; Węglarz L
    Molecules; 2017 Oct; 22(10):. PubMed ID: 28972559
    [No Abstract]   [Full Text] [Related]  

  • 33. Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells.
    Dong Y; Jia L; Wang X; Tan X; Xu J; Deng Z; Jiang T; Rainov NG; Li B; Ren H
    Int J Oncol; 2011 Feb; 38(2):555-69. PubMed ID: 21152856
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Anticancer profile and anti-inflammatory effect of new N-(2-((4-(1,3-diphenyl-1H-pyrazol-4-yl)pyridine sulfonamide derivatives.
    Abdel-Maksoud MS; Mohamed Hassan R; Abdel-Sattar El-Azzouny A; Nabil Aboul-Enein M; Oh CH
    Bioorg Chem; 2021 Dec; 117():105424. PubMed ID: 34678604
    [TBL] [Abstract][Full Text] [Related]  

  • 35. AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C.
    Vucicevic L; Misirkic M; Janjetovic K; Harhaji-Trajkovic L; Prica M; Stevanovic D; Isenovic E; Sudar E; Sumarac-Dumanovic M; Micic D; Trajkovic V
    Biochem Pharmacol; 2009 Jun; 77(11):1684-93. PubMed ID: 19428322
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The inhibition of BDNF/TrkB/PI3K/Akt signal mediated by AG1601 promotes apoptosis in malignant glioma.
    Yin H; Jiang Y; Zhang Y; Ge H; Yang Z
    J Cell Biochem; 2019 Nov; 120(11):18771-18781. PubMed ID: 31219215
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Benzochalcones bearing pyrazoline moieties show anti-colorectal cancer activities and selective inhibitory effects on aurora kinases.
    Shin SY; Yoon H; Hwang D; Ahn S; Kim DW; Koh D; Lee YH; Lim Y
    Bioorg Med Chem; 2013 Nov; 21(22):7018-24. PubMed ID: 24095020
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors.
    Sever B; Altıntop MD; Radwan MO; Özdemir A; Otsuka M; Fujita M; Ciftci HI
    Eur J Med Chem; 2019 Nov; 182():111648. PubMed ID: 31493743
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Current status of carbazole hybrids as anticancer agents.
    Wang G; Sun S; Guo H
    Eur J Med Chem; 2022 Feb; 229():113999. PubMed ID: 34838335
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design, synthesis and biological evaluation of novel 1,3,4-trisubstituted pyrazole derivatives as potential chemotherapeutic agents for hepatocellular carcinoma.
    Harras MF; Sabour R
    Bioorg Chem; 2018 Aug; 78():149-157. PubMed ID: 29567429
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.