BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 31954012)

  • 1. Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene.
    Cheng S; Wu T; Li Y; Huang J; Cai T
    Med Sci Monit; 2020 Jan; 26():e918528. PubMed ID: 31954012
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Nephroprotective Effect of MS-275 on Lipopolysaccharide (LPS)-Induced Acute Kidney Injury by Inhibiting Reactive Oxygen Species (ROS)-Oxidative Stress and Endoplasmic Reticulum Stress.
    Zhang H; Zhang W; Jiao F; Li X; Zhang H; Wang L; Gong Z
    Med Sci Monit; 2018 Apr; 24():2620-2630. PubMed ID: 29704392
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines.
    Xiao JJ; Huang Y; Dai Z; Sadée W; Chen J; Liu S; Marcucci G; Byrd J; Covey JM; Wright J; Grever M; Chan KK
    J Pharmacol Exp Ther; 2005 Jul; 314(1):467-75. PubMed ID: 15833893
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The histone deacetylase inhibitor FK228 given prior to adenovirus infection can boost infection in melanoma xenograft model systems.
    Goldsmith ME; Aguila A; Steadman K; Martinez A; Steinberg SM; Alley MC; Waud WR; Bates SE; Fojo T
    Mol Cancer Ther; 2007 Feb; 6(2):496-505. PubMed ID: 17308048
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase inhibitor, Romidepsin (FK228) inhibits endometrial cancer cell growth through augmentation of p53-p21 pathway.
    Li LH; Zhang PR; Cai PY; Li ZC
    Biomed Pharmacother; 2016 Aug; 82():161-6. PubMed ID: 27470351
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Involvement of the tumor necrosis factor (TNF)/TNF receptor system in leukemic cell apoptosis induced by histone deacetylase inhibitor depsipeptide (FK228).
    Sutheesophon K; Nishimura N; Kobayashi Y; Furukawa Y; Kawano M; Itoh K; Kano Y; Ishii H; Furukawa Y
    J Cell Physiol; 2005 May; 203(2):387-97. PubMed ID: 15515013
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase inhibitor FK228 activates tumor suppressor Prdx1 with apoptosis induction in esophageal cancer cells.
    Hoshino I; Matsubara H; Hanari N; Mori M; Nishimori T; Yoneyama Y; Akutsu Y; Sakata H; Matsushita K; Seki N; Ochiai T
    Clin Cancer Res; 2005 Nov; 11(21):7945-52. PubMed ID: 16278420
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor efficacy of FK228, a novel histone deacetylase inhibitor, depends on the effect on expression of angiogenesis factors.
    Sasakawa Y; Naoe Y; Noto T; Inoue T; Sasakawa T; Matsuo M; Manda T; Mutoh S
    Biochem Pharmacol; 2003 Sep; 66(6):897-906. PubMed ID: 12963476
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression.
    Nishida K; Komiyama T; Miyazawa S; Shen ZN; Furumatsu T; Doi H; Yoshida A; Yamana J; Yamamura M; Ninomiya Y; Inoue H; Asahara H
    Arthritis Rheum; 2004 Oct; 50(10):3365-76. PubMed ID: 15476220
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The regulation of cytochrome P450 2E1 during LPS-induced inflammation in the rat.
    Abdulla D; Goralski KB; Renton KW
    Toxicol Appl Pharmacol; 2006 Oct; 216(1):1-10. PubMed ID: 16712892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The molecular mechanism regulating 24-hour rhythm of CYP2E1 expression in the mouse liver.
    Matsunaga N; Ikeda M; Takiguchi T; Koyanagi S; Ohdo S
    Hepatology; 2008 Jul; 48(1):240-51. PubMed ID: 18537186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivo.
    Sasakawa Y; Naoe Y; Inoue T; Sasakawa T; Matsuo M; Manda T; Mutoh S
    Biochem Pharmacol; 2002 Oct; 64(7):1079-90. PubMed ID: 12234611
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Romidepsin (FK228) improves the survival of allogeneic skin grafts through downregulating the production of donor-specific antibody via suppressing the IRE1α-XBP1 pathway.
    Guo Y; Song S; DU X; Tian L; Zhang M; Zhou H; Chen ZK; Chang S
    J Zhejiang Univ Sci B; 2022 May; 23(5):392-406. PubMed ID: 35557040
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of class I HDACs attenuates renal interstitial fibrosis in a murine model.
    Yang M; Chen G; Zhang X; Guo Y; Yu Y; Tian L; Chang S; Chen ZK
    Pharmacol Res; 2019 Apr; 142():192-204. PubMed ID: 30807866
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.
    Panicker J; Li Z; McMahon C; Sizer C; Steadman K; Piekarz R; Bates SE; Thiele CJ
    Cell Cycle; 2010 May; 9(9):1830-8. PubMed ID: 20404560
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synchronous recruitment of epigenetic modifiers to endotoxin synergistically activated Tnf-α gene in acute kidney injury.
    Bomsztyk K; Flanagin S; Mar D; Mikula M; Johnson A; Zager R; Denisenko O
    PLoS One; 2013; 8(7):e70322. PubMed ID: 23936185
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Romidepsin induces cell cycle arrest, apoptosis, histone hyperacetylation and reduces matrix metalloproteinases 2 and 9 expression in bortezomib sensitized non-small cell lung cancer cells.
    Karthik S; Sankar R; Varunkumar K; Ravikumar V
    Biomed Pharmacother; 2014 Apr; 68(3):327-34. PubMed ID: 24485799
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors.
    Saijo K; Imamura J; Narita K; Oda A; Shimodaira H; Katoh T; Ishioka C
    Cancer Sci; 2015 Feb; 106(2):208-15. PubMed ID: 25492515
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Inhibitory effect of a novel histone deacetylases inhibitor FK228 on human colon cancer HCT-116 cells in vitro and in vivo].
    Xu DB; Wang YL; Yue Y; Wu SC; Ding H
    Zhonghua Zhong Liu Za Zhi; 2013 Nov; 35(11):814-8. PubMed ID: 24447477
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Class IIa HDAC inhibitor TMP195 alleviates lipopolysaccharide-induced acute kidney injury.
    Zhang W; Guan Y; Bayliss G; Zhuang S
    Am J Physiol Renal Physiol; 2020 Dec; 319(6):F1015-F1026. PubMed ID: 33017186
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.