BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 31963558)

  • 1. Differential Expression of Nicotine Acetylcholine Receptors Associates with Human Breast Cancer and Mediates Antitumor Activity of αO-Conotoxin GeXIVA.
    Sun Z; Zhangsun M; Dong S; Liu Y; Qian J; Zhangsun D; Luo S
    Mar Drugs; 2020 Jan; 18(1):. PubMed ID: 31963558
    [TBL] [Abstract][Full Text] [Related]  

  • 2. αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors.
    Sun Z; Bao J; Zhangsun M; Dong S; Zhangsun D; Luo S
    Mar Drugs; 2020 Apr; 18(4):. PubMed ID: 32272701
    [TBL] [Abstract][Full Text] [Related]  

  • 3. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.
    Zhangsun D; Zhu X; Kaas Q; Wu Y; Craik DJ; McIntosh JM; Luo S
    Neuropharmacology; 2017 Dec; 127():243-252. PubMed ID: 28416445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cervical Cancer Correlates with the Differential Expression of Nicotinic Acetylcholine Receptors and Reveals Therapeutic Targets.
    Liu Y; Qian J; Sun Z; Zhangsun D; Luo S
    Mar Drugs; 2019 Apr; 17(5):. PubMed ID: 31035425
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models.
    Kryukova EV; Ivanov IA; Lebedev DS; Spirova EN; Egorova NS; Zouridakis M; Kasheverov IE; Tzartos SJ; Tsetlin VI
    Mar Drugs; 2018 Nov; 16(12):. PubMed ID: 30469507
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4].
    Xu P; Zhang P; Zhu X; Wu Y; Harvey PJ; Kaas Q; Zhangsun D; Craik DJ; Luo S
    J Med Chem; 2023 Jul; 66(14):10092-10107. PubMed ID: 37464764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of nicotinic acetylcholine receptor subunits in different lung cancer cell lines and the inhibitory effect of alpha-conotoxin TxID on lung cancer cell growth.
    Qian J; Liu YQ; Sun ZH; Zhangsun DT; Luo SL
    Eur J Pharmacol; 2019 Dec; 865():172674. PubMed ID: 31634461
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overexpression and activation of the alpha9-nicotinic receptor during tumorigenesis in human breast epithelial cells.
    Lee CH; Huang CS; Chen CS; Tu SH; Wang YJ; Chang YJ; Tam KW; Wei PL; Cheng TC; Chu JS; Chen LC; Wu CH; Ho YS
    J Natl Cancer Inst; 2010 Sep; 102(17):1322-35. PubMed ID: 20733118
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.
    Luo S; Zhangsun D; Harvey PJ; Kaas Q; Wu Y; Zhu X; Hu Y; Li X; Tsetlin VI; Christensen S; Romero HK; McIntyre M; Dowell C; Baxter JC; Elmslie KS; Craik DJ; McIntosh JM
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4026-35. PubMed ID: 26170295
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins.
    Chen CS; Lee CH; Hsieh CD; Ho CT; Pan MH; Huang CS; Tu SH; Wang YJ; Chen LC; Chang YJ; Wei PL; Yang YY; Wu CH; Ho YS
    Breast Cancer Res Treat; 2011 Jan; 125(1):73-87. PubMed ID: 20229177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.
    Christensen SB; Bandyopadhyay PK; Olivera BM; McIntosh JM
    Biochem Pharmacol; 2015 Aug; 96(4):349-56. PubMed ID: 26074268
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The α9α10 Nicotinic Acetylcholine Receptor Antagonist αO-Conotoxin GeXIVA[1,2] Alleviates and Reverses Chemotherapy-Induced Neuropathic Pain.
    Wang H; Li X; Zhangsun D; Yu G; Su R; Luo S
    Mar Drugs; 2019 May; 17(5):. PubMed ID: 31060282
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?
    Mohammadi SA; Christie MJ
    Toxins (Basel); 2015 Sep; 7(10):3916-32. PubMed ID: 26426047
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA.
    Xu P; Kaas Q; Wu Y; Zhu X; Li X; Harvey PJ; Zhangsun D; Craik DJ; Luo S
    J Med Chem; 2020 Feb; 63(4):1564-1575. PubMed ID: 31986036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of serum, enzyme, thiol, and forced degradation on the stabilities of αO-Conotoxin GeXIVA[1,2] and GeXIVA [1,4].
    Yu S; Wu Y; Xu P; Wang S; Zhangsun D; Luo S
    Chem Biol Drug Des; 2018 May; 91(5):1030-1041. PubMed ID: 29316361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combination treatment with luteolin and quercetin enhances antiproliferative effects in nicotine-treated MDA-MB-231 cells by down-regulating nicotinic acetylcholine receptors.
    Shih YL; Liu HC; Chen CS; Hsu CH; Pan MH; Chang HW; Chang CH; Chen FC; Ho CT; Yang YY; Ho YS
    J Agric Food Chem; 2010 Jan; 58(1):235-41. PubMed ID: 19921817
    [TBL] [Abstract][Full Text] [Related]  

  • 17. αO-Conotoxin GeXIVA[1,2] Reduced Neuropathic Pain and Changed Gene Expression in Chronic Oxaliplatin-Induced Neuropathy Mice Model.
    Wang H; Li X; Qiao Y; Wang M; Wang W; McIntosh JM; Zhangsun D; Luo S
    Mar Drugs; 2024 Jan; 22(1):. PubMed ID: 38276651
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lyophilization Serves as an Effective Strategy for Drug Development of the α9α10 Nicotinic Acetylcholine Receptor Antagonist α-Conotoxin GeXIVA[1,2].
    Li Z; Han X; Hong X; Li X; Gao J; Zhang H; Zheng A
    Mar Drugs; 2021 Feb; 19(3):. PubMed ID: 33668830
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of nicotinic acetylcholine receptors in cell proliferation and tumour invasion in broncho-pulmonary carcinomas.
    Medjber K; Freidja ML; Grelet S; Lorenzato M; Maouche K; Nawrocki-Raby B; Birembaut P; Polette M; Tournier JM
    Lung Cancer; 2015 Mar; 87(3):258-64. PubMed ID: 25601486
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1.
    Indurthi DC; Pera E; Kim HL; Chu C; McLeod MD; McIntosh JM; Absalom NL; Chebib M
    Biochem Pharmacol; 2014 May; 89(1):131-40. PubMed ID: 24548457
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.