These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 31964872)

  • 1. Structural insight into small molecule action on Frizzleds.
    Kozielewicz P; Turku A; Bowin CF; Petersen J; Valnohova J; Cañizal MCA; Ono Y; Inoue A; Hoffmann C; Schulte G
    Nat Commun; 2020 Jan; 11(1):414. PubMed ID: 31964872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular Pharmacology of Class F Receptor Activation.
    Kozielewicz P; Turku A; Schulte G
    Mol Pharmacol; 2020 Feb; 97(2):62-71. PubMed ID: 31591260
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment.
    Valnohova J; Kowalski-Jahn M; Sunahara RK; Schulte G
    J Biol Chem; 2018 Nov; 293(46):17875-17887. PubMed ID: 30237173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The tyrosine Y250
    Strakova K; Matricon P; Yokota C; Arthofer E; Bernatik O; Rodriguez D; Arenas E; Carlsson J; Bryja V; Schulte G
    Cell Signal; 2017 Oct; 38():85-96. PubMed ID: 28668722
    [TBL] [Abstract][Full Text] [Related]  

  • 5. WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction.
    Bowin CF; Kozielewicz P; Grätz L; Kowalski-Jahn M; Schihada H; Schulte G
    Sci Signal; 2023 Apr; 16(779):eabo4974. PubMed ID: 37014927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization.
    Strakova K; Kowalski-Jahn M; Gybel T; Valnohova J; Dhople VM; Harnos J; Bernatik O; Ganji RS; Zdrahal Z; Mulder J; Lindskog C; Bryja V; Schulte G
    J Biol Chem; 2018 Nov; 293(48):18477-18493. PubMed ID: 30309985
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Progress in the development of modulators targeting Frizzleds.
    Chuan J; Li W; Pan S; Jiang Z; Shi J; Yang Z
    Pharmacol Res; 2024 Aug; 206():107286. PubMed ID: 38936522
    [TBL] [Abstract][Full Text] [Related]  

  • 8. WNT Stimulation Dissociates a Frizzled 4 Inactive-State Complex with Gα12/13.
    Arthofer E; Hot B; Petersen J; Strakova K; Jäger S; Grundmann M; Kostenis E; Gutkind JS; Schulte G
    Mol Pharmacol; 2016 Oct; 90(4):447-59. PubMed ID: 27458145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frizzleds and WNT/β-catenin signaling--The black box of ligand-receptor selectivity, complex stoichiometry and activation kinetics.
    Schulte G
    Eur J Pharmacol; 2015 Sep; 763(Pt B):191-5. PubMed ID: 26003275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Assessment of Frizzled 6 membrane mobility by FRAP supports G protein coupling and reveals WNT-Frizzled selectivity.
    Kilander MB; Dahlström J; Schulte G
    Cell Signal; 2014 Sep; 26(9):1943-9. PubMed ID: 24873871
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6.
    Kilander MB; Petersen J; Andressen KW; Ganji RS; Levy FO; Schuster J; Dahl N; Bryja V; Schulte G
    FASEB J; 2014 May; 28(5):2293-305. PubMed ID: 24500924
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Frizzled receptors (FZDs) in Wnt signaling: potential therapeutic targets for human cancers.
    Liu HY; Sun XJ; Xiu SY; Zhang XY; Wang ZQ; Gu YL; Yi CX; Liu JY; Dai YS; Yuan X; Liao HP; Liu ZM; Pang XC; Li TC
    Acta Pharmacol Sin; 2024 Aug; 45(8):1556-1570. PubMed ID: 38632318
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of the Frizzled 4 receptor in a ligand-free state.
    Yang S; Wu Y; Xu TH; de Waal PW; He Y; Pu M; Chen Y; DeBruine ZJ; Zhang B; Zaidi SA; Popov P; Guo Y; Han GW; Lu Y; Suino-Powell K; Dong S; Harikumar KG; Miller LJ; Katritch V; Xu HE; Shui W; Stevens RC; Melcher K; Zhao S; Xu F
    Nature; 2018 Aug; 560(7720):666-670. PubMed ID: 30135577
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of Potent, Selective Surrogate WNT Molecules and Their Application in Defining Frizzled Requirements.
    Chen H; Lu C; Ouyang B; Zhang H; Huang Z; Bhatia D; Lee SJ; Shah D; Sura A; Yeh WC; Li Y
    Cell Chem Biol; 2020 May; 27(5):598-609.e4. PubMed ID: 32220333
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Frizzled family of unconventional G-protein-coupled receptors.
    Schulte G; Bryja V
    Trends Pharmacol Sci; 2007 Oct; 28(10):518-25. PubMed ID: 17884187
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural and Druggability Landscape of Frizzled G Protein-Coupled Receptors.
    Zhang X; Dong S; Xu F
    Trends Biochem Sci; 2018 Dec; 43(12):1033-1046. PubMed ID: 30309741
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1.
    Harnoš J; Cañizal MCA; Jurásek M; Kumar J; Holler C; Schambony A; Hanáková K; Bernatík O; Zdráhal Z; Gömöryová K; Gybeľ T; Radaszkiewicz TW; Kravec M; Trantírek L; Ryneš J; Dave Z; Fernández-Llamazares AI; Vácha R; Tripsianes K; Hoffmann C; Bryja V
    Nat Commun; 2019 Apr; 10(1):1804. PubMed ID: 31000703
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Frizzleds act as dynamic pharmacological entities.
    Schulte G; Scharf MM; Bous J; Voss JH; Grätz L; Kozielewicz P
    Trends Pharmacol Sci; 2024 May; 45(5):419-429. PubMed ID: 38594145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Frizzleds as GPCRs - More Conventional Than We Thought!
    Schulte G; Wright SC
    Trends Pharmacol Sci; 2018 Sep; 39(9):828-842. PubMed ID: 30049420
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation barriers in Class F G protein-coupled receptors revealed by umbrella sampling simulations.
    Agostino M; Pohl SÖ
    Org Biomol Chem; 2020 Dec; 18(48):9816-9825. PubMed ID: 33290484
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.