These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 31966066)

  • 1. Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen-125 secretion in ovarian carcinoma.
    Antoun S; Atallah D; Tahtouh R; Assaf MD; Moubarak M; Ayoub EN; Chahine G; Hilal G
    Oncol Lett; 2020 Feb; 19(2):1338-1350. PubMed ID: 31966066
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Telomerase inhibition decreases alpha-fetoprotein expression and secretion by hepatocellular carcinoma cell lines: in vitro and in vivo study.
    Tahtouh R; Azzi AS; Alaaeddine N; Chamat S; Bouharoun-Tayoun H; Wardi L; Raad I; Sarkis R; Antoun NA; Hilal G
    PLoS One; 2015; 10(3):e0119512. PubMed ID: 25822740
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of human telomerase reverse transcriptase mediates the senescence of mesenchymal stem cells through the PI3K/AKT signaling pathway.
    Zhao Q; Wang XY; Yu XX; Zhai YX; He X; Wu S; Shi YA
    Int J Mol Med; 2015 Sep; 36(3):857-64. PubMed ID: 26178664
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptors.
    Mahfouz N; Tahtouh R; Alaaeddine N; El Hajj J; Sarkis R; Hachem R; Raad I; Hilal G
    PLoS One; 2017; 12(6):e0179202. PubMed ID: 28594907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The telomerase activity and expression of hTERT gene can serve as indicators in the anti-cancer treatment of human ovarian cancer.
    Sun PM; Wei LH; Luo MY; Liu G; Wang JL; Mustea A; Könsgen D; Lichtenegger W; Sehouli J
    Eur J Obstet Gynecol Reprod Biol; 2007 Feb; 130(2):249-57. PubMed ID: 16519988
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents.
    Cookson JC; Dai F; Smith V; Heald RA; Laughton CA; Stevens MF; Burger AM
    Mol Pharmacol; 2005 Dec; 68(6):1551-8. PubMed ID: 16150933
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of rapamycin on the mechanistic target of rapamycin (mTOR) pathway and telomerase in breast cancer cells.
    Gopalakrishnan K; Venkatesan S; Low ESH; Hande MP
    Mutat Res Genet Toxicol Environ Mutagen; 2018 Dec; 836(Pt B):103-113. PubMed ID: 30442335
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.
    Ci X; Li B; Ma X; Kong F; Zheng C; Björkholm M; Jia J; Xu D
    Oncotarget; 2015 Nov; 6(35):38079-92. PubMed ID: 26472030
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells.
    Kawauchi K; Ihjima K; Yamada O
    J Immunol; 2005 May; 174(9):5261-9. PubMed ID: 15843522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mild hyperoxia limits hTR levels, telomerase activity, and telomere length maintenance in hTERT-transduced bone marrow endothelial cells.
    Napier CE; Veas LA; Kan CY; Taylor LM; Yuan J; Wen VW; James A; O'Brien TA; Lock RB; MacKenzie KL
    Biochim Biophys Acta; 2010 Oct; 1803(10):1142-53. PubMed ID: 20619302
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Telomere length and hTERT expression in patients with colorectal carcinoma.
    Rosenberg R; Gertler R; Stricker D; Lassmann S; Werner M; Nekarda H; Siewert JR
    Recent Results Cancer Res; 2003; 162():177-81. PubMed ID: 12790332
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AKT activation and telomerase reverse transcriptase expression are concurrently associated with prognosis of gastric cancer.
    Sasaki T; Kuniyasu H; Luo Y; Kitayoshi M; Tanabe E; Kato D; Shinya S; Fujii K; Ohmori H; Yamashita Y
    Pathobiology; 2014; 81(1):36-41. PubMed ID: 23969493
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
    Zhang D; Sun X; Liu J; Xie X; Cui W; Zhu Y
    Arterioscler Thromb Vasc Biol; 2015 Jan; 35(1):71-8. PubMed ID: 25359865
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development.
    Waki K; Anno K; Ono T; Ide T; Chayama K; Tahara H
    Cancer Sci; 2010 Jul; 101(7):1678-85. PubMed ID: 20456367
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner.
    Zhao P; Wang C; Fu Z; You Y; Cheng Y; Lu X; Lu A; Liu N; Pu P; Kang C; Salford LG; Fan X
    Int J Oncol; 2007 Aug; 31(2):361-8. PubMed ID: 17611693
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Zinc sulfate contributes to promote telomere length extension via increasing telomerase gene expression, telomerase activity and change in the TERT gene promoter CpG island methylation status of human adipose-derived mesenchymal stem cells.
    Farahzadi R; Fathi E; Mesbah-Namin SA; Zarghami N
    PLoS One; 2017; 12(11):e0188052. PubMed ID: 29145503
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Growth arrest in ovarian cancer cells by hTERT inhibition short-hairpin RNA targeting human telomerase reverse transcriptase induces immediate growth inhibition but not necessarily induces apoptosis in ovarian cancer cells.
    Luo Y; Yi Y; Yao Z
    Cancer Invest; 2009 Dec; 27(10):960-70. PubMed ID: 19909010
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro.
    Yang SM; Fang DC; Yang JL; Chen L; Luo YH; Liang GP
    Eur J Cancer Prev; 2008 Jun; 17(3):209-17. PubMed ID: 18414191
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesions.
    Lantuejoul S; Soria JC; Morat L; Lorimier P; Moro-Sibilot D; Sabatier L; Brambilla C; Brambilla E
    Clin Cancer Res; 2005 Mar; 11(5):2074-82. PubMed ID: 15756034
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Telomerase activity and hTERT mRNA expression can be heterogeneous and does not correlate with telomere length in soft tissue sarcomas.
    Yan P; Benhattar J; Coindre JM; Guillou L
    Int J Cancer; 2002 Apr; 98(6):851-6. PubMed ID: 11948462
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.