These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 31968243)

  • 21. Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form.
    Yang H; Yang S; Jing L; Huang L; Chen L; Zhao X; Yang W; Pan Y; Yin P; Qin ZS; Tang B; Li S; Li XJ
    Nat Commun; 2020 May; 11(1):2582. PubMed ID: 32444599
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effect of early embryonic deletion of huntingtin from pyramidal neurons on the development and long-term survival of neurons in cerebral cortex and striatum.
    Dragatsis I; Dietrich P; Ren H; Deng YP; Del Mar N; Wang HB; Johnson IM; Jones KR; Reiner A
    Neurobiol Dis; 2018 Mar; 111():102-117. PubMed ID: 29274742
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease.
    Schmidt ME; Buren C; Mackay JP; Cheung D; Dal Cengio L; Raymond LA; Hayden MR
    BMC Biol; 2018 Jun; 16(1):58. PubMed ID: 29945611
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region.
    Sapp E; Seeley C; Iuliano M; Weisman E; Vodicka P; DiFiglia M; Kegel-Gleason KB
    Neurobiol Dis; 2020 Jul; 141():104950. PubMed ID: 32439598
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cellular Analysis of Silencing the Huntington's Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice.
    Keeler AM; Sapp E; Chase K; Sottosanti E; Danielson E; Pfister E; Stoica L; DiFiglia M; Aronin N; Sena-Esteves M
    J Huntingtons Dis; 2016 Oct; 5(3):239-248. PubMed ID: 27689620
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.
    Yin X; Manczak M; Reddy PH
    Hum Mol Genet; 2016 May; 25(9):1739-53. PubMed ID: 26908605
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Impaired Replenishment of Cortico-Striatal Synaptic Glutamate in Huntington's Disease Mouse Model.
    Buren C; Tu G; Raymond LA
    J Huntingtons Dis; 2020; 9(2):149-161. PubMed ID: 32310183
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice.
    Pancani T; Day M; Tkatch T; Wokosin DL; González-Rodríguez P; Kondapalli J; Xie Z; Chen Y; Beaumont V; Surmeier DJ
    Nat Commun; 2023 Mar; 14(1):1398. PubMed ID: 36914640
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inducing huntingtin inclusion formation in primary neuronal cell culture and in vivo by high-capacity adenoviral vectors expressing truncated and full-length huntingtin with polyglutamine expansion.
    Huang B; Schiefer J; Sass C; Kosinski CM; Kochanek S
    J Gene Med; 2008 Mar; 10(3):269-79. PubMed ID: 18067195
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice.
    Naydenov AV; Sepers MD; Swinney K; Raymond LA; Palmiter RD; Stella N
    Neurobiol Dis; 2014 Nov; 71():140-50. PubMed ID: 25134728
    [TBL] [Abstract][Full Text] [Related]  

  • 31. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).
    Ratovitski T; Arbez N; Stewart JC; Chighladze E; Ross CA
    Cell Cycle; 2015; 14(11):1716-29. PubMed ID: 25927346
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.
    Marco S; Giralt A; Petrovic MM; Pouladi MA; Martínez-Turrillas R; Martínez-Hernández J; Kaltenbach LS; Torres-Peraza J; Graham RK; Watanabe M; Luján R; Nakanishi N; Lipton SA; Lo DC; Hayden MR; Alberch J; Wesseling JF; Pérez-Otaño I
    Nat Med; 2013 Aug; 19(8):1030-8. PubMed ID: 23852340
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Disassociation of histone deacetylase-3 from normal huntingtin underlies mutant huntingtin neurotoxicity.
    Bardai FH; Verma P; Smith C; Rawat V; Wang L; D'Mello SR
    J Neurosci; 2013 Jul; 33(29):11833-8. PubMed ID: 23864673
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment.
    Gafni J; Papanikolaou T; Degiacomo F; Holcomb J; Chen S; Menalled L; Kudwa A; Fitzpatrick J; Miller S; Ramboz S; Tuunanen PI; Lehtimäki KK; Yang XW; Park L; Kwak S; Howland D; Park H; Ellerby LM
    J Neurosci; 2012 May; 32(22):7454-65. PubMed ID: 22649225
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Expanded huntingtin activates the c-Jun terminal kinase/c-Jun pathway prior to aggregate formation in striatal neurons in culture.
    Garcia M; Charvin D; Caboche J
    Neuroscience; 2004; 127(4):859-70. PubMed ID: 15312898
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Normal aging modulates the neurotoxicity of mutant huntingtin.
    Diguet E; Petit F; Escartin C; Cambon K; Bizat N; Dufour N; Hantraye P; Déglon N; Brouillet E
    PLoS One; 2009; 4(2):e4637. PubMed ID: 19247483
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synaptic pathology in Huntington's disease: Beyond the corticostriatal pathway.
    Barry J; Bui MTN; Levine MS; Cepeda C
    Neurobiol Dis; 2022 Jan; 162():105574. PubMed ID: 34848336
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Wild-type huntingtin plays a role in brain development and neuronal survival.
    Reiner A; Dragatsis I; Zeitlin S; Goldowitz D
    Mol Neurobiol; 2003 Dec; 28(3):259-76. PubMed ID: 14709789
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms.
    Giralt A; Saavedra A; Alberch J; Pérez-Navarro E
    J Huntingtons Dis; 2012; 1(2):155-73. PubMed ID: 25063329
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
    Shirendeb UP; Calkins MJ; Manczak M; Anekonda V; Dufour B; McBride JL; Mao P; Reddy PH
    Hum Mol Genet; 2012 Jan; 21(2):406-20. PubMed ID: 21997870
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.