203 related articles for article (PubMed ID: 31974475)
1. Phenome-wide functional dissection of pleiotropic effects highlights key molecular pathways for human complex traits.
Shikov AE; Skitchenko RK; Predeus AV; Barbitoff YA
Sci Rep; 2020 Jan; 10(1):1037. PubMed ID: 31974475
[TBL] [Abstract][Full Text] [Related]
2. A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics.
Zhang Z; Jung J; Kim A; Suboc N; Gazal S; Mancuso N
Am J Hum Genet; 2023 Nov; 110(11):1863-1874. PubMed ID: 37879338
[TBL] [Abstract][Full Text] [Related]
3. A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.
Shameer K; Denny JC; Ding K; Jouni H; Crosslin DR; de Andrade M; Chute CG; Peissig P; Pacheco JA; Li R; Bastarache L; Kho AN; Ritchie MD; Masys DR; Chisholm RL; Larson EB; McCarty CA; Roden DM; Jarvik GP; Kullo IJ
Hum Genet; 2014 Jan; 133(1):95-109. PubMed ID: 24026423
[TBL] [Abstract][Full Text] [Related]
4. Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits.
Zhao B; Shan Y; Yang Y; Yu Z; Li T; Wang X; Luo T; Zhu Z; Sullivan P; Zhao H; Li Y; Zhu H
Nat Commun; 2021 May; 12(1):2878. PubMed ID: 34001886
[TBL] [Abstract][Full Text] [Related]
5. PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics.
Lee CH; Shi H; Pasaniuc B; Eskin E; Han B
Am J Hum Genet; 2021 Jan; 108(1):36-48. PubMed ID: 33352115
[TBL] [Abstract][Full Text] [Related]
6. A global overview of pleiotropy and genetic architecture in complex traits.
Watanabe K; Stringer S; Frei O; Umićević Mirkov M; de Leeuw C; Polderman TJC; van der Sluis S; Andreassen OA; Neale BM; Posthuma D
Nat Genet; 2019 Sep; 51(9):1339-1348. PubMed ID: 31427789
[TBL] [Abstract][Full Text] [Related]
7. Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Li X; Meng X; He Y; Spiliopoulou A; Timofeeva M; Wei WQ; Gifford A; Yang T; Varley T; Tzoulaki I; Joshi P; Denny JC; Mckeigue P; Campbell H; Theodoratou E
PLoS Med; 2019 Oct; 16(10):e1002937. PubMed ID: 31626644
[TBL] [Abstract][Full Text] [Related]
8. Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR.
Hutchinson A; Reales G; Willis T; Wallace C
PLoS Genet; 2021 Oct; 17(10):e1009853. PubMed ID: 34669738
[TBL] [Abstract][Full Text] [Related]
9. Revealing polygenic pleiotropy using genetic risk scores for asthma.
Dapas M; Lee YL; Wentworth-Sheilds W; Im HK; Ober C; Schoettler N
HGG Adv; 2023 Oct; 4(4):100233. PubMed ID: 37663543
[TBL] [Abstract][Full Text] [Related]
10. Identification of novel SNPs associated with coronary artery disease and birth weight using a pleiotropic cFDR method.
Wu X; Lin X; Li Q; Wang Z; Zhang N; Tian M; Wang X; Deng H; Tan H
Aging (Albany NY); 2020 Dec; 13(3):3618-3644. PubMed ID: 33411684
[TBL] [Abstract][Full Text] [Related]
11. An integrative functional genomics framework for effective identification of novel regulatory variants in genome-phenome studies.
Zhao J; Cheng F; Jia P; Cox N; Denny JC; Zhao Z
Genome Med; 2018 Jan; 10(1):7. PubMed ID: 29378629
[TBL] [Abstract][Full Text] [Related]
12. Investigation of multi-trait associations using pathway-based analysis of GWAS summary statistics.
Pei G; Sun H; Dai Y; Liu X; Zhao Z; Jia P
BMC Genomics; 2019 Feb; 20(Suppl 1):79. PubMed ID: 30712509
[TBL] [Abstract][Full Text] [Related]
13. Knowledge-based analysis of genetic associations of rheumatoid arthritis to inform studies searching for pleiotropic genes: a literature review and network analysis.
Zheng W; Rao S
Arthritis Res Ther; 2015 Aug; 17(1):202. PubMed ID: 26253105
[TBL] [Abstract][Full Text] [Related]
14. Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes.
Andreassen OA; McEvoy LK; Thompson WK; Wang Y; Reppe S; Schork AJ; Zuber V; Barrett-Connor E; Gautvik K; Aukrust P; Karlsen TH; Djurovic S; Desikan RS; Dale AM;
Hypertension; 2014 Apr; 63(4):819-26. PubMed ID: 24396023
[TBL] [Abstract][Full Text] [Related]
15. COLOCdb: a comprehensive resource for multi-model colocalization of complex traits.
Pan S; Kang H; Liu X; Li S; Yang P; Wu M; Yuan N; Lin S; Zheng Q; Jia P
Nucleic Acids Res; 2024 Jan; 52(D1):D871-D881. PubMed ID: 37941154
[TBL] [Abstract][Full Text] [Related]
16. Leveraging Genome and Phenome-Wide Association Studies to Investigate Genetic Risk of Acute Lymphoblastic Leukemia.
Semmes EC; Vijayakrishnan J; Zhang C; Hurst JH; Houlston RS; Walsh KM
Cancer Epidemiol Biomarkers Prev; 2020 Aug; 29(8):1606-1614. PubMed ID: 32467347
[TBL] [Abstract][Full Text] [Related]
17. Pleiotropy informed adaptive association test of multiple traits using genome-wide association study summary data.
Masotti M; Guo B; Wu B
Biometrics; 2019 Dec; 75(4):1076-1085. PubMed ID: 31021400
[TBL] [Abstract][Full Text] [Related]
18. Detection and interpretation of shared genetic influences on 42 human traits.
Pickrell JK; Berisa T; Liu JZ; Ségurel L; Tung JY; Hinds DA
Nat Genet; 2016 Jul; 48(7):709-17. PubMed ID: 27182965
[TBL] [Abstract][Full Text] [Related]
19. Determining Which Phenotypes Underlie a Pleiotropic Signal.
Majumdar A; Haldar T; Witte JS
Genet Epidemiol; 2016 Jul; 40(5):366-81. PubMed ID: 27238845
[TBL] [Abstract][Full Text] [Related]
20. Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative.
Fritsche LG; Gruber SB; Wu Z; Schmidt EM; Zawistowski M; Moser SE; Blanc VM; Brummett CM; Kheterpal S; Abecasis GR; Mukherjee B
Am J Hum Genet; 2018 Jun; 102(6):1048-1061. PubMed ID: 29779563
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]