350 related articles for article (PubMed ID: 31985402)
1. Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.
Domingues AF; Kulkarni R; Giotopoulos G; Gupta S; Vinnenberg L; Arede L; Foerner E; Khalili M; Adao RR; Johns A; Tan S; Zeka K; Huntly BJ; Prabakaran S; Pina C
Elife; 2020 Jan; 9():. PubMed ID: 31985402
[TBL] [Abstract][Full Text] [Related]
2. Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development.
Arede L; Pina C
Exp Hematol; 2021 Jan; 93():25-37. PubMed ID: 33223444
[TBL] [Abstract][Full Text] [Related]
3. Contributions of transcriptional noise to leukaemia evolution: KAT2A as a case-study.
Pina C
Philos Trans R Soc Lond B Biol Sci; 2024 Apr; 379(1900):20230052. PubMed ID: 38432321
[TBL] [Abstract][Full Text] [Related]
4. Convergent epigenetic evolution drives relapse in acute myeloid leukemia.
Nuno K; Azizi A; Koehnke T; Lareau C; Ediriwickrema A; Corces MR; Satpathy AT; Majeti R
Elife; 2024 Apr; 13():. PubMed ID: 38647535
[TBL] [Abstract][Full Text] [Related]
5. Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity.
Moris N; Edri S; Seyres D; Kulkarni R; Domingues AF; Balayo T; Frontini M; Pina C
Stem Cells; 2018 Dec; 36(12):1828-1838. PubMed ID: 30270482
[TBL] [Abstract][Full Text] [Related]
6. HBO1 is required for the maintenance of leukaemia stem cells.
MacPherson L; Anokye J; Yeung MM; Lam EYN; Chan YC; Weng CF; Yeh P; Knezevic K; Butler MS; Hoegl A; Chan KL; Burr ML; Gearing LJ; Willson T; Liu J; Choi J; Yang Y; Bilardi RA; Falk H; Nguyen N; Stupple PA; Peat TS; Zhang M; de Silva M; Carrasco-Pozo C; Avery VM; Khoo PS; Dolezal O; Dennis ML; Nuttall S; Surjadi R; Newman J; Ren B; Leaver DJ; Sun Y; Baell JB; Dovey O; Vassiliou GS; Grebien F; Dawson SJ; Street IP; Monahan BJ; Burns CJ; Choudhary C; Blewitt ME; Voss AK; Thomas T; Dawson MA
Nature; 2020 Jan; 577(7789):266-270. PubMed ID: 31827282
[TBL] [Abstract][Full Text] [Related]
7. Divergent functions of histone acetyltransferases KAT2A and KAT2B in keratinocyte self-renewal and differentiation.
Walters BW; Tan TJ; Tan CT; Dube CT; Lee KT; Koh J; Ong YHB; Tan VXH; Jahan FRS; Lim XN; Wan Y; Lim CY
J Cell Sci; 2023 Jun; 136(12):. PubMed ID: 37259855
[TBL] [Abstract][Full Text] [Related]
8. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Zuber J; Shi J; Wang E; Rappaport AR; Herrmann H; Sison EA; Magoon D; Qi J; Blatt K; Wunderlich M; Taylor MJ; Johns C; Chicas A; Mulloy JC; Kogan SC; Brown P; Valent P; Bradner JE; Lowe SW; Vakoc CR
Nature; 2011 Aug; 478(7370):524-8. PubMed ID: 21814200
[TBL] [Abstract][Full Text] [Related]
9. HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML.
Li Z; Wang F; Tian X; Long J; Ling B; Zhang W; Xu J; Liang A
J Exp Clin Cancer Res; 2021 Jun; 40(1):210. PubMed ID: 34167558
[TBL] [Abstract][Full Text] [Related]
10. Bortezomib suppresses self-renewal and leukemogenesis of leukemia stem cell by NF-ĸB-dependent inhibition of CDK6 in MLL-rearranged myeloid leukemia.
Zhou B; Qin Y; Zhou J; Ruan J; Xiong F; Dong J; Huang X; Yu Z; Gao S
J Cell Mol Med; 2021 Mar; 25(6):3124-3135. PubMed ID: 33599085
[TBL] [Abstract][Full Text] [Related]
11. Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia.
Sachs K; Sarver AL; Noble-Orcutt KE; LaRue RS; Antony ML; Chang D; Lee Y; Navis CM; Hillesheim AL; Nykaza IR; Ha NA; Hansen CJ; Karadag FK; Bergerson RJ; Verneris MR; Meredith MM; Schomaker ML; Linden MA; Myers CL; Largaespada DA; Sachs Z
Cancer Res; 2020 Feb; 80(3):458-470. PubMed ID: 31784425
[TBL] [Abstract][Full Text] [Related]
12. Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients.
Ali MA; Naka K; Yoshida A; Fuse K; Kasada A; Hoshii T; Tadokoro Y; Ueno M; Ohta K; Kobayashi M; Takahashi C; Hirao A
Biochem Biophys Res Commun; 2014 Jul; 450(1):837-43. PubMed ID: 24960197
[TBL] [Abstract][Full Text] [Related]
13. Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.
Diffner E; Beck D; Gudgin E; Thoms JA; Knezevic K; Pridans C; Foster S; Goode D; Lim WK; Boelen L; Metzeler KH; Micklem G; Bohlander SK; Buske C; Burnett A; Ottersbach K; Vassiliou GS; Olivier J; Wong JW; Göttgens B; Huntly BJ; Pimanda JE
Blood; 2013 Mar; 121(12):2289-300. PubMed ID: 23327922
[TBL] [Abstract][Full Text] [Related]
14. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.
Almotiri A; Alzahrani H; Menendez-Gonzalez JB; Abdelfattah A; Alotaibi B; Saleh L; Greene A; Georgiou M; Gibbs A; Alsayari A; Taha S; Thomas LA; Shah D; Edkins S; Giles P; Stemmler MP; Brabletz S; Brabletz T; Boyd AS; Siebzehnrubl FA; Rodrigues NP
J Clin Invest; 2021 Jan; 131(1):. PubMed ID: 33108352
[TBL] [Abstract][Full Text] [Related]
15. KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia.
Arede L; Foerner E; Wind S; Kulkarni R; Domingues AF; Giotopoulos G; Kleinwaechter S; Mollenhauer-Starkl M; Davison H; Chandru A; Asby R; Samarista R; Gupta S; Forte D; Curti A; Scheer E; Huntly BJP; Tora L; Pina C
Blood Adv; 2022 Jan; 6(1):165-180. PubMed ID: 34654054
[TBL] [Abstract][Full Text] [Related]
16. Tracing the origins of relapse in acute myeloid leukaemia to stem cells.
Shlush LI; Mitchell A; Heisler L; Abelson S; Ng SWK; Trotman-Grant A; Medeiros JJF; Rao-Bhatia A; Jaciw-Zurakowsky I; Marke R; McLeod JL; Doedens M; Bader G; Voisin V; Xu C; McPherson JD; Hudson TJ; Wang JCY; Minden MD; Dick JE
Nature; 2017 Jul; 547(7661):104-108. PubMed ID: 28658204
[TBL] [Abstract][Full Text] [Related]
17. IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.
Park SM; Cho H; Thornton AM; Barlowe TS; Chou T; Chhangawala S; Fairchild L; Taggart J; Chow A; Schurer A; Gruet A; Witkin MD; Kim JH; Shevach EM; Krivtsov A; Armstrong SA; Leslie C; Kharas MG
Cell Stem Cell; 2019 Jan; 24(1):153-165.e7. PubMed ID: 30472158
[TBL] [Abstract][Full Text] [Related]
18. A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Tzelepis K; Koike-Yusa H; De Braekeleer E; Li Y; Metzakopian E; Dovey OM; Mupo A; Grinkevich V; Li M; Mazan M; Gozdecka M; Ohnishi S; Cooper J; Patel M; McKerrell T; Chen B; Domingues AF; Gallipoli P; Teichmann S; Ponstingl H; McDermott U; Saez-Rodriguez J; Huntly BJP; Iorio F; Pina C; Vassiliou GS; Yusa K
Cell Rep; 2016 Oct; 17(4):1193-1205. PubMed ID: 27760321
[TBL] [Abstract][Full Text] [Related]
19. LncRNA MAGI2-AS3 inhibits the self-renewal of leukaemic stem cells by promoting TET2-dependent DNA demethylation of the LRIG1 promoter in acute myeloid leukaemia.
Chen L; Fan X; Zhu J; Chen X; Liu Y; Zhou H
RNA Biol; 2020 Jun; 17(6):784-793. PubMed ID: 32174258
[TBL] [Abstract][Full Text] [Related]
20. Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia.
Menendez-Gonzalez JB; Vukovic M; Abdelfattah A; Saleh L; Almotiri A; Thomas LA; Agirre-Lizaso A; Azevedo A; Menezes AC; Tornillo G; Edkins S; Kong K; Giles P; Anjos-Afonso F; Tonks A; Boyd AS; Kranc KR; Rodrigues NP
Stem Cell Reports; 2019 Aug; 13(2):291-306. PubMed ID: 31378673
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]