BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 31986051)

  • 1. All-Atom Simulations Disclose How Cytochrome Reductase Reshapes the Substrate Access/Egress Routes of Its Partner CYP450s.
    Ritacco I; Saltalamacchia A; Spinello A; Ippoliti E; Magistrato A
    J Phys Chem Lett; 2020 Feb; 11(4):1189-1193. PubMed ID: 31986051
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Post-Translational Regulation of CYP450s Metabolism As Revealed by All-Atoms Simulations of the Aromatase Enzyme.
    Ritacco I; Spinello A; Ippoliti E; Magistrato A
    J Chem Inf Model; 2019 Jun; 59(6):2930-2940. PubMed ID: 31033287
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effector role of cytochrome P450 reductase for androstenedione binding to human aromatase.
    Zhang C; Catucci G; Di Nardo G; Gilardi G
    Int J Biol Macromol; 2020 Dec; 164():510-517. PubMed ID: 32698066
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P450-The Wonderful Nanomachine Revealed through Dynamic Simulations of the Catalytic Cycle.
    Dubey KD; Shaik S
    Acc Chem Res; 2019 Feb; 52(2):389-399. PubMed ID: 30633519
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conformational changes of the NADPH-dependent cytochrome P450 reductase in the course of electron transfer to cytochromes P450.
    Laursen T; Jensen K; Møller BL
    Biochim Biophys Acta; 2011 Jan; 1814(1):132-8. PubMed ID: 20624491
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [NADPH-cytochrome P450 reductase, not only the partner of cytochrome P450].
    Wiśniewska A; Jagiełło K; Mazerska Z
    Postepy Biochem; 2009; 55(3):272-8. PubMed ID: 19928583
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of the complex formation, interaction and electron transfer pathway between the "open" conformation of NADPH-cytochrome P450 reductase and aromatase.
    Dai Y; Zhen J; Zhang X; Zhong Y; Liu S; Sun Z; Guo Y; Wu Q
    Steroids; 2015 Sep; 101():116-24. PubMed ID: 26087061
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure, dynamics, and function of the monooxygenase P450 BM-3: insights from computer simulations studies.
    Roccatano D
    J Phys Condens Matter; 2015 Jul; 27(27):273102. PubMed ID: 26061496
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational Landscape of Cytochrome P450 Reductase Interactions.
    Sellner M; Fischer A; Don CG; Smieško M
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33498551
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A large-scale comparative analysis of affinity, thermodynamics and functional characteristics of interactions of twelve cytochrome P450 isoforms and their redox partners.
    Yablokov EO; Sushko TA; Ershov PV; Florinskaya AV; Gnedenko OV; Shkel TV; Grabovec IP; Strushkevich NV; Kaluzhskiy LA; Usanov SA; Gilep AA; Ivanov AS
    Biochimie; 2019 Jul; 162():156-166. PubMed ID: 31034920
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Single or Multiple Access Channels to the CYP450s Active Site? An Answer from Free Energy Simulations of the Human Aromatase Enzyme.
    Magistrato A; Sgrignani J; Krause R; Cavalli A
    J Phys Chem Lett; 2017 May; 8(9):2036-2042. PubMed ID: 28423275
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequence-function correlation of aromatase and its interaction with reductase.
    Hong Y; Li H; Yuan YC; Chen S
    J Steroid Biochem Mol Biol; 2010 Feb; 118(4-5):203-6. PubMed ID: 19944754
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s.
    Krishnan S; Wasalathanthri D; Zhao L; Schenkman JB; Rusling JF
    J Am Chem Soc; 2011 Feb; 133(5):1459-65. PubMed ID: 21214177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probing membrane enhanced protein-protein interactions in a minimal redox complex of cytochrome-P450 and P450-reductase.
    Mahajan M; Ravula T; Prade E; Anantharamaiah GM; Ramamoorthy A
    Chem Commun (Camb); 2019 May; 55(41):5777-5780. PubMed ID: 31041432
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An enzymatically active chimeric protein containing the hydrophilic form of NADPH-cytochrome P450 reductase fused to the membrane-binding domain of cytochrome b5.
    Gilep AA; Guryev OL; Usanov SA; Estabrook RW
    Biochem Biophys Res Commun; 2001 Jun; 284(4):937-41. PubMed ID: 11409883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs.
    Prade E; Mahajan M; Im SC; Zhang M; Gentry KA; Anantharamaiah GM; Waskell L; Ramamoorthy A
    Angew Chem Int Ed Engl; 2018 Jul; 57(28):8458-8462. PubMed ID: 29722926
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes.
    Shimada T; Mernaugh RL; Guengerich FP
    Arch Biochem Biophys; 2005 Mar; 435(1):207-16. PubMed ID: 15680923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Homology modeling of the three membrane proteins of the dhurrin metabolon: catalytic sites, membrane surface association and protein-protein interactions.
    Jensen K; Osmani SA; Hamann T; Naur P; Møller BL
    Phytochemistry; 2011 Dec; 72(17):2113-23. PubMed ID: 21620426
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human placental estrogen synthetase (aromatase). Effect of environment on the kinetics of protein-protein and substrate-protein interactions and the production of 19-oxygenated androgen intermediates in the purified reconstituted cytochrome P450 enzyme system.
    Sethumadhavan K; Bellino FL
    J Steroid Biochem Mol Biol; 1991 Sep; 39(3):381-94. PubMed ID: 1911429
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding.
    Esteves F; Urban P; Rueff J; Truan G; Kranendonk M
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32933097
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.