133 related articles for article (PubMed ID: 31987694)
1. Optimisation of estrogen receptor subtype-selectivity of a 4-Aryl-4H-chromene scaffold previously identified by virtual screening.
Carr M; Knox AJS; Nevin DK; O'Boyle N; Wang S; Egan B; McCabe T; Twamley B; Zisterer DM; Lloyd DG; Meegan MJ
Bioorg Med Chem; 2020 Mar; 28(5):115261. PubMed ID: 31987694
[TBL] [Abstract][Full Text] [Related]
2. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group.
Kemnitzer W; Drewe J; Jiang S; Zhang H; Wang Y; Zhao J; Jia S; Herich J; Labreque D; Storer R; Meerovitch K; Bouffard D; Rej R; Denis R; Blais C; Lamothe S; Attardo G; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
J Med Chem; 2004 Dec; 47(25):6299-310. PubMed ID: 15566300
[TBL] [Abstract][Full Text] [Related]
3. Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells.
Carr M; Knox AJ; Lloyd DG; Zisterer DM; Meegan MJ
J Enzyme Inhib Med Chem; 2016; 31(sup3):117-130. PubMed ID: 27476825
[TBL] [Abstract][Full Text] [Related]
4. Development of potential anticancer agents and apoptotic inducers based on 4-aryl-4H chromene scaffold: Design, synthesis, biological evaluation and insight on their proliferation inhibition mechanism.
Elshemy HAH; Zaki MA; Mahmoud AM; Khan SI; Chittiboyina AG; Kamal AM
Bioorg Chem; 2022 Jan; 118():105475. PubMed ID: 34800886
[TBL] [Abstract][Full Text] [Related]
5. Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft.
Saxena R; Fatima I; Chandra V; Blesson CS; Kharkwal G; Hussain MK; Hajela K; Roy BG; Dwivedi A
Steroids; 2013 Nov; 78(11):1071-86. PubMed ID: 23891847
[TBL] [Abstract][Full Text] [Related]
6. 4-Aryl-4H-chromene-3-carbonitrile derivatives: evaluation of Src kinase inhibitory and anticancer activities.
Fallah-Tafti A; Tiwari R; Shirazi AN; Akbarzadeh T; Mandal D; Shafiee A; Parang K; Foroumadi A
Med Chem; 2011 Sep; 7(5):466-72. PubMed ID: 21801146
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of novel chromene derivatives of expected antitumor activity.
Kandeel MM; Kamal AM; Abdelall EK; Elshemy HA
Eur J Med Chem; 2013 Jan; 59():183-93. PubMed ID: 23220647
[TBL] [Abstract][Full Text] [Related]
8. Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against resistant cancer cells, dual β-tubulin/c-Src inhibition, cell cycle arrest and apoptosis induction.
Abdelall EKA; A H Elshemy H; Labib MB; E A Mohamed F
Bioorg Chem; 2022 Mar; 120():105591. PubMed ID: 34998122
[TBL] [Abstract][Full Text] [Related]
9. Antiestrogenically active 2-benzyl-1,1-diarylbut-2-enes: synthesis, structure-activity relationships and molecular modeling study for flexible estrogen receptor antagonists.
Lloyd DG; Smith HM; O'Sullivan T; Knox AS; Zisterer DM; Meegan MJ
Med Chem; 2006 Mar; 2(2):147-68. PubMed ID: 16787364
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, Biological Investigation and Docking Study of Novel Chromen Derivatives as Anti-Cancer Agents.
Dube PN; Sakle NS; Dhawale SA; More SA; Mokale SN
Anticancer Agents Med Chem; 2019; 19(9):1150-1160. PubMed ID: 30848213
[TBL] [Abstract][Full Text] [Related]
11. Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene.
Alblewi FF; Okasha RM; Hritani ZM; Mohamed HM; El-Nassag MAA; Halawa AH; Mora A; Fouda AM; Assiri MA; Al-Dies AM; Afifi TH; El-Agrody AM
Bioorg Chem; 2019 Jun; 87():560-571. PubMed ID: 30928878
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of novel 1,2,3-triazole/isoxazole functionalized 2H-Chromene derivatives and their cytotoxic activity.
Ratnakar Reddy K; Sambasiva Rao P; Jitender Dev G; Poornachandra Y; Ganesh Kumar C; Shanthan Rao P; Narsaiah B
Bioorg Med Chem Lett; 2014 Apr; 24(7):1661-3. PubMed ID: 24641975
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, estrogen receptor binding affinity and molecular docking of pyrimidine-piperazine-chromene and -quinoline conjugates.
Parveen I; Ahmed N; Idrees D; Khan P; Hassan MI
Bioorg Med Chem Lett; 2017 Sep; 27(18):4493-4499. PubMed ID: 28797797
[TBL] [Abstract][Full Text] [Related]
14. Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Qin J; Qu S; Zhu K; Cheng Y; Pan G; Jing W; Liu X; Sun X; Liu L
Bioorg Med Chem; 2021 Feb; 32():116003. PubMed ID: 33461148
[TBL] [Abstract][Full Text] [Related]
15. Anti-proliferative and apoptotic effects of the derivatives from 4-aryl-4H-chromene family on human leukemia K562 cells.
Aryapour H; Mahdavi M; Mohebbi SR; Zali MR; Foroumadi A
Arch Pharm Res; 2012 Sep; 35(9):1573-82. PubMed ID: 23054714
[TBL] [Abstract][Full Text] [Related]
16. Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring.
Norman BH; Richardson TI; Dodge JA; Pfeifer LA; Durst GL; Wang Y; Durbin JD; Krishnan V; Dinn SR; Liu S; Reilly JE; Ryter KT
Bioorg Med Chem Lett; 2007 Sep; 17(18):5082-5. PubMed ID: 17662603
[TBL] [Abstract][Full Text] [Related]
17. New 2-Imino-2H-Chromene-3(N-aryl)carboxamides as Potential Cytotoxic Agents.
Gill RK; Kumari J; Bariwal J
Anticancer Agents Med Chem; 2017; 17(1):85-92. PubMed ID: 26961315
[TBL] [Abstract][Full Text] [Related]
18. 4H-Chromene-based anticancer agents towards multi-drug resistant HL60/MX2 human leukemia: SAR at the 4th and 6th positions.
Puppala M; Zhao X; Casemore D; Zhou B; Aridoss G; Narayanapillai S; Xing C
Bioorg Med Chem; 2016 Mar; 24(6):1292-7. PubMed ID: 26867486
[TBL] [Abstract][Full Text] [Related]
19. Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha.
Zhang B; Kiefer JR; Blake RA; Chang JH; Hartman S; Ingalla ER; Kleinheinz T; Mody V; Nannini M; Ortwine DF; Ran Y; Sambrone A; Sampath D; Vinogradova M; Zhong Y; Nwachukwu JC; Nettles KW; Lai T; Liao J; Zheng X; Chen H; Wang X; Liang J
Bioorg Med Chem Lett; 2019 Apr; 29(7):905-911. PubMed ID: 30732944
[TBL] [Abstract][Full Text] [Related]
20. Syntheses of conformationally restricted benzopyran based triarylethylenes as growth inhibitors of carcinoma cells.
Ahmad MI; Dixit S; Konwar R; Vasdev PG; Yadav AK; Tripathi S; Gupta MM; Sharma A; Gupta A
Bioorg Med Chem Lett; 2017 Nov; 27(22):5040-5045. PubMed ID: 29054359
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
