BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 31988461)

  • 1. iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates.
    Laperle AH; Sances S; Yucer N; Dardov VJ; Garcia VJ; Ho R; Fulton AN; Jones MR; Roxas KM; Avalos P; West D; Banuelos MG; Shu Z; Murali R; Maidment NT; Van Eyk JE; Tagliati M; Svendsen CN
    Nat Med; 2020 Feb; 26(2):289-299. PubMed ID: 31988461
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus.
    Devine MJ; Ryten M; Vodicka P; Thomson AJ; Burdon T; Houlden H; Cavaleri F; Nagano M; Drummond NJ; Taanman JW; Schapira AH; Gwinn K; Hardy J; Lewis PA; Kunath T
    Nat Commun; 2011 Aug; 2():440. PubMed ID: 21863007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.
    Lang C; Campbell KR; Ryan BJ; Carling P; Attar M; Vowles J; Perestenko OV; Bowden R; Baig F; Kasten M; Hu MT; Cowley SA; Webber C; Wade-Martins R
    Cell Stem Cell; 2019 Jan; 24(1):93-106.e6. PubMed ID: 30503143
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Generation of three clones (JUCGRMi002-A, B, C) of induced pluripotent stem cells from a Parkinson's disease patient with SNCA duplication.
    Ishikawa KI; Shiga T; Yoshino H; Nishioka K; Hattori N; Akamatsu W
    Stem Cell Res; 2024 Feb; 74():103296. PubMed ID: 38154385
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Establishment of induced pluripotent stem cell lines derived from Parkinson's disease Mexican patients: A sporadic (UNAMi002-A) and a familial (UNAMi003-A) case carrying a mutation in PINK1.
    Flores-Ponce X; López-Ornelas A; Escobedo-Avila I; Rodríguez-Violante M; Dávila-Ortiz de Montellano D; Cervantes-Arriaga A; Monroy-Jaramillo N; Campos-Romo A; Velasco I
    Stem Cell Res; 2024 Apr; 76():103337. PubMed ID: 38359473
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein.
    Cuddy LK; Wani WY; Morella ML; Pitcairn C; Tsutsumi K; Fredriksen K; Justman CJ; Grammatopoulos TN; Belur NR; Zunke F; Subramanian A; Affaneh A; Lansbury PT; Mazzulli JR
    Neuron; 2019 Dec; 104(5):869-884.e11. PubMed ID: 31648898
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons.
    Chung CY; Khurana V; Auluck PK; Tardiff DF; Mazzulli JR; Soldner F; Baru V; Lou Y; Freyzon Y; Cho S; Mungenast AE; Muffat J; Mitalipova M; Pluth MD; Jui NT; Schüle B; Lippard SJ; Tsai LH; Krainc D; Buchwald SL; Jaenisch R; Lindquist S
    Science; 2013 Nov; 342(6161):983-7. PubMed ID: 24158904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human iPSC-based modeling of late-onset disease via progerin-induced aging.
    Miller JD; Ganat YM; Kishinevsky S; Bowman RL; Liu B; Tu EY; Mandal PK; Vera E; Shim JW; Kriks S; Taldone T; Fusaki N; Tomishima MJ; Krainc D; Milner TA; Rossi DJ; Studer L
    Cell Stem Cell; 2013 Dec; 13(6):691-705. PubMed ID: 24315443
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induced pluripotent stem cells for modeling and cell therapy of Parkinson's disease.
    Csöbönyeiová M; Danišovič Ľ; Polák Š
    Neural Regen Res; 2016 May; 11(5):727-8. PubMed ID: 27335549
    [No Abstract]   [Full Text] [Related]  

  • 10. Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease.
    Schweitzer JS; Song B; Herrington TM; Park TY; Lee N; Ko S; Jeon J; Cha Y; Kim K; Li Q; Henchcliffe C; Kaplitt M; Neff C; Rapalino O; Seo H; Lee IH; Kim J; Kim T; Petsko GA; Ritz J; Cohen BM; Kong SW; Leblanc P; Carter BS; Kim KS
    N Engl J Med; 2020 May; 382(20):1926-1932. PubMed ID: 32402162
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy.
    Shahnawaz M; Mukherjee A; Pritzkow S; Mendez N; Rabadia P; Liu X; Hu B; Schmeichel A; Singer W; Wu G; Tsai AL; Shirani H; Nilsson KPR; Low PA; Soto C
    Nature; 2020 Feb; 578(7794):273-277. PubMed ID: 32025029
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reversing a model of Parkinson's disease with in situ converted nigral neurons.
    Qian H; Kang X; Hu J; Zhang D; Liang Z; Meng F; Zhang X; Xue Y; Maimon R; Dowdy SF; Devaraj NK; Zhou Z; Mobley WC; Cleveland DW; Fu XD
    Nature; 2020 Jun; 582(7813):550-556. PubMed ID: 32581380
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Soluble TREM2 is elevated in Parkinson's disease subgroups with increased CSF tau.
    Wilson EN; Swarovski MS; Linortner P; Shahid M; Zuckerman AJ; Wang Q; Channappa D; Minhas PS; Mhatre SD; Plowey ED; Quinn JF; Zabetian CP; Tian L; Longo FM; Cholerton B; Montine TJ; Poston KL; Andreasson KI
    Brain; 2020 Mar; 143(3):932-943. PubMed ID: 32065223
    [TBL] [Abstract][Full Text] [Related]  

  • 14. α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease.
    Lindestam Arlehamn CS; Dhanwani R; Pham J; Kuan R; Frazier A; Rezende Dutra J; Phillips E; Mallal S; Roederer M; Marder KS; Amara AW; Standaert DG; Goldman JG; Litvan I; Peters B; Sulzer D; Sette A
    Nat Commun; 2020 Apr; 11(1):1875. PubMed ID: 32313102
    [TBL] [Abstract][Full Text] [Related]  

  • 15. β-adrenoreceptors and the risk of Parkinson's disease.
    Hopfner F; Höglinger GU; Kuhlenbäumer G; Pottegård A; Wod M; Christensen K; Tanner CM; Deuschl G
    Lancet Neurol; 2020 Mar; 19(3):247-254. PubMed ID: 31999942
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stem Cell Modeling: A Promising New Avenue for Young-Onset PD Research.
    Zhang W; Yang C
    Mov Disord; 2020 May; 35(5):759. PubMed ID: 32282958
    [No Abstract]   [Full Text] [Related]  

  • 17. Method to combat Parkinson's disease by astrocyte-to-neuron conversion.
    Arenas E
    Nature; 2020 Jun; 582(7813):489-490. PubMed ID: 32581373
    [No Abstract]   [Full Text] [Related]  

  • 18. Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
    Bryois J; Skene NG; Hansen TF; Kogelman LJA; Watson HJ; Liu Z; ; ; ; Brueggeman L; Breen G; Bulik CM; Arenas E; Hjerling-Leffler J; Sullivan PF
    Nat Genet; 2020 May; 52(5):482-493. PubMed ID: 32341526
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases.
    Bartels T; De Schepper S; Hong S
    Science; 2020 Oct; 370(6512):66-69. PubMed ID: 33004513
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy.
    Wang XJ; Ma MM; Zhou LB; Jiang XY; Hao MM; Teng RKF; Wu E; Tang BS; Li JY; Teng JF; Ding XB
    Nat Commun; 2020 Feb; 11(1):934. PubMed ID: 32071315
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.