349 related articles for article (PubMed ID: 31996678)
1. mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.
Martinez Calejman C; Trefely S; Entwisle SW; Luciano A; Jung SM; Hsiao W; Torres A; Hung CM; Li H; Snyder NW; Villén J; Wellen KE; Guertin DA
Nat Commun; 2020 Jan; 11(1):575. PubMed ID: 31996678
[TBL] [Abstract][Full Text] [Related]
2. mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer.
Chen Y; Qian J; He Q; Zhao H; Toral-Barza L; Shi C; Zhang X; Wu J; Yu K
Oncotarget; 2016 May; 7(18):25224-40. PubMed ID: 27015560
[TBL] [Abstract][Full Text] [Related]
3. ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.
Zhao S; Torres A; Henry RA; Trefely S; Wallace M; Lee JV; Carrer A; Sengupta A; Campbell SL; Kuo YM; Frey AJ; Meurs N; Viola JM; Blair IA; Weljie AM; Metallo CM; Snyder NW; Andrews AJ; Wellen KE
Cell Rep; 2016 Oct; 17(4):1037-1052. PubMed ID: 27760311
[TBL] [Abstract][Full Text] [Related]
4. ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection.
Vysochan A; Sengupta A; Weljie AM; Alwine JC; Yu Y
Proc Natl Acad Sci U S A; 2017 Feb; 114(8):E1528-E1535. PubMed ID: 28167750
[TBL] [Abstract][Full Text] [Related]
5. Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling.
Entwisle SW; Martinez Calejman C; Valente AS; Lawrence RT; Hung CM; Guertin DA; Villén J
Mol Cell Proteomics; 2020 Jul; 19(7):1104-1119. PubMed ID: 32234964
[TBL] [Abstract][Full Text] [Related]
6. Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells.
Xu H; Luo J; Ma G; Zhang X; Yao D; Li M; Loor JJ
J Cell Physiol; 2018 Feb; 233(2):1005-1016. PubMed ID: 28407230
[TBL] [Abstract][Full Text] [Related]
7. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.
Zhao S; Jang C; Liu J; Uehara K; Gilbert M; Izzo L; Zeng X; Trefely S; Fernandez S; Carrer A; Miller KD; Schug ZT; Snyder NW; Gade TP; Titchenell PM; Rabinowitz JD; Wellen KE
Nature; 2020 Mar; 579(7800):586-591. PubMed ID: 32214246
[TBL] [Abstract][Full Text] [Related]
8. Exploring the Role of ATP-Citrate Lyase in the Immune System.
Dominguez M; Brüne B; Namgaladze D
Front Immunol; 2021; 12():632526. PubMed ID: 33679780
[TBL] [Abstract][Full Text] [Related]
9. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Tang Y; Wallace M; Sanchez-Gurmaches J; Hsiao WY; Li H; Lee PL; Vernia S; Metallo CM; Guertin DA
Nat Commun; 2016 Apr; 7():11365. PubMed ID: 27098609
[TBL] [Abstract][Full Text] [Related]
10. Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells.
Dominguez M; Truemper V; Mota AC; Brüne B; Namgaladze D
Front Immunol; 2022; 13():906127. PubMed ID: 36439127
[TBL] [Abstract][Full Text] [Related]
11. Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation.
Zheng W; Tasselli L; Li TM; Chua KF
Genes (Basel); 2021 Sep; 12(9):. PubMed ID: 34573442
[TBL] [Abstract][Full Text] [Related]
12. Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Jung SM; Hung CM; Hildebrand SR; Sanchez-Gurmaches J; Martinez-Pastor B; Gengatharan JM; Wallace M; Mukhopadhyay D; Martinez Calejman C; Luciano AK; Hsiao WY; Tang Y; Li H; Daniels DL; Mostoslavsky R; Metallo CM; Guertin DA
Mol Cell; 2019 Aug; 75(4):807-822.e8. PubMed ID: 31442424
[TBL] [Abstract][Full Text] [Related]
13. ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms.
Zaidi N; Royaux I; Swinnen JV; Smans K
Mol Cancer Ther; 2012 Sep; 11(9):1925-35. PubMed ID: 22718913
[TBL] [Abstract][Full Text] [Related]
14. Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Hung CM; Calejman CM; Sanchez-Gurmaches J; Li H; Clish CB; Hettmer S; Wagers AJ; Guertin DA
Cell Rep; 2014 Jul; 8(1):256-71. PubMed ID: 25001283
[TBL] [Abstract][Full Text] [Related]
15. Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.
Yenilmez B; Kelly M; Zhang GF; Wetoska N; Ilkayeva OR; Min K; Rowland L; DiMarzio C; He W; Raymond N; Lifshitz L; Pan M; Han X; Xie J; Friedline RH; Kim JK; Gao G; Herman MA; Newgard CB; Czech MP
J Biol Chem; 2022 Oct; 298(10):102401. PubMed ID: 35988648
[TBL] [Abstract][Full Text] [Related]
16. mTORC2 Regulates Lipogenic Gene Expression through PPAR
Guo Z; Zhao K; Feng X; Yan D; Yao R; Chen Y; Bao L; Wang Z
Biomed Res Int; 2019; 2019():5196028. PubMed ID: 31223619
[TBL] [Abstract][Full Text] [Related]
17. Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis.
Izzo LT; Trefely S; Demetriadou C; Drummond JM; Mizukami T; Kuprasertkul N; Farria AT; Nguyen PTT; Murali N; Reich L; Kantner DS; Shaffer J; Affronti H; Carrer A; Andrews A; Capell BC; Snyder NW; Wellen KE
Sci Adv; 2023 May; 9(18):eadf0115. PubMed ID: 37134161
[TBL] [Abstract][Full Text] [Related]
18. Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells.
Hatipoglu A; Menon D; Levy T; Frias MA; Foster DA
PLoS One; 2022; 17(10):e0276579. PubMed ID: 36269753
[TBL] [Abstract][Full Text] [Related]
19. Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.
Sivanand S; Rhoades S; Jiang Q; Lee JV; Benci J; Zhang J; Yuan S; Viney I; Zhao S; Carrer A; Bennett MJ; Minn AJ; Weljie AM; Greenberg RA; Wellen KE
Mol Cell; 2017 Jul; 67(2):252-265.e6. PubMed ID: 28689661
[TBL] [Abstract][Full Text] [Related]
20. Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling.
Zhang D; Tong X; Arthurs B; Guha A; Rui L; Kamath A; Inoki K; Yin L
J Biol Chem; 2014 Sep; 289(37):25925-35. PubMed ID: 25063808
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
