BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

475 related articles for article (PubMed ID: 32007561)

  • 1. CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway.
    van Rooyen D; Yadav R; Scott EE; Swart AC
    J Steroid Biochem Mol Biol; 2020 May; 199():105614. PubMed ID: 32007561
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor pathway.
    van Rooyen D; Gent R; Barnard L; Swart AC
    J Steroid Biochem Mol Biol; 2018 Apr; 178():203-212. PubMed ID: 29277707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro.
    Gent R; du Toit T; Swart AC
    J Steroid Biochem Mol Biol; 2019 Jul; 191():105369. PubMed ID: 31039398
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adrenal C11-oxy C
    Barnard L; Gent R; van Rooyen D; Swart AC
    J Steroid Biochem Mol Biol; 2017 Nov; 174():86-95. PubMed ID: 28774496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The 11β-hydroxyandrostenedione pathway and C11-oxy C
    du Toit T; Swart AC
    J Steroid Biochem Mol Biol; 2020 Feb; 196():105497. PubMed ID: 31626910
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C11-hydroxy and C11-oxo C
    Gent R; Van Rooyen D; Atkin SL; Swart AC
    Int J Mol Sci; 2023 Dec; 25(1):. PubMed ID: 38203272
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C
    Gent R; du Toit T; Bloem LM; Swart AC
    J Steroid Biochem Mol Biol; 2019 May; 189():116-126. PubMed ID: 30825506
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17.
    Gupta MK; Guryev OL; Auchus RJ
    Arch Biochem Biophys; 2003 Oct; 418(2):151-60. PubMed ID: 14522586
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The metabolic fate and receptor interaction of 16α-hydroxyprogesterone and its 5α-reduced metabolite, 16α-hydroxy-dihydroprogesterone.
    van Rooyen D; du Toit T; Louw-du Toit R; Africander D; Swart P; Swart AC
    Mol Cell Endocrinol; 2017 Feb; 441():86-98. PubMed ID: 27664517
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 11β-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione.
    Swart AC; Schloms L; Storbeck KH; Bloem LM; Toit Td; Quanson JL; Rainey WE; Swart P
    J Steroid Biochem Mol Biol; 2013 Nov; 138():132-42. PubMed ID: 23685396
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inefficient UGT-conjugation of adrenal 11β-hydroxyandrostenedione metabolites highlights C11-oxy C
    du Toit T; Swart AC
    Mol Cell Endocrinol; 2018 Feb; 461():265-276. PubMed ID: 28939401
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The activities of 5α-reductase and 17,20-lyase determine the direction through androgen synthesis pathways in patients with 21-hydroxylase deficiency.
    Kamrath C; Hartmann MF; Remer T; Wudy SA
    Steroids; 2012 Nov; 77(13):1391-7. PubMed ID: 22951291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C11-oxy C
    du Toit T; Finken MJJ; Hamer HM; Heijboer AC; Swart AC
    Steroids; 2018 Oct; 138():1-5. PubMed ID: 29883615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of steroidogenesis and steroidogenic enzyme functions.
    Luu-The V
    J Steroid Biochem Mol Biol; 2013 Sep; 137():176-82. PubMed ID: 23770321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Formation of 5alpha-reduced C19-steroids from progesterone in vitro by a pathway through 5alpha-reduced C21-steroids in ovaries of late prepubertal rats.
    Karakawa T; Kurachi K; Aono T; Matsumoto K
    Endocrinology; 1976 Mar; 98(3):571-9. PubMed ID: 1261488
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Profiling adrenal 11β-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC
    du Toit T; Bloem LM; Quanson JL; Ehlers R; Serafin AM; Swart AC
    J Steroid Biochem Mol Biol; 2017 Feb; 166():54-67. PubMed ID: 27345701
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Back where it belongs: 11β-hydroxyandrostenedione compels the re-assessment of C11-oxy androgens in steroidogenesis.
    Barnard L; du Toit T; Swart AC
    Mol Cell Endocrinol; 2021 Apr; 525():111189. PubMed ID: 33539964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of 52 C
    du Toit T; van Rooyen D; Stander MA; Atkin SL; Swart AC
    J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Sep; 1152():122243. PubMed ID: 32593151
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pathways and genes involved in steroid hormone metabolism in male pigs: a review and update.
    Robic A; Faraut T; Prunier A
    J Steroid Biochem Mol Biol; 2014 Mar; 140():44-55. PubMed ID: 24239507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Turning the spotlight on the C11-oxy androgens in human fetal development.
    du Toit T; Swart AC
    J Steroid Biochem Mol Biol; 2021 Sep; 212():105946. PubMed ID: 34171490
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.