BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 32015438)

  • 1. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.
    Gan W; Dai X; Dai X; Xie J; Yin S; Zhu J; Wang C; Liu Y; Guo J; Wang M; Liu J; Hu J; Quinton RJ; Ganem NJ; Liu P; Asara JM; Pandolfi PP; Yang Y; He Z; Gao G; Wei W
    Nat Cell Biol; 2020 Feb; 22(2):246-256. PubMed ID: 32015438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LncRNA coordinates Hippo and mTORC1 pathway activation in cancer.
    Zhang S; Liang S; Wu D; Guo H; Ma K; Liu L
    Cell Death Dis; 2021 Aug; 12(9):822. PubMed ID: 34462427
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells.
    Ahmed AR; Owens RJ; Stubbs CD; Parker AW; Hitchman R; Yadav RB; Dumoux M; Hawes C; Botchway SW
    Sci Rep; 2019 Mar; 9(1):3408. PubMed ID: 30833605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Circadian Rheb oscillation alters the dynamics of hepatic mTORC1 activity and mitochondrial morphology.
    Yuan Q; Chen M; Yang W; Xiao B
    FEBS Lett; 2021 Feb; 595(3):360-369. PubMed ID: 33247956
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells.
    Peng H; Kasada A; Ueno M; Hoshii T; Tadokoro Y; Nomura N; Ito C; Takase Y; Vu HT; Kobayashi M; Xiao B; Worley PF; Hirao A
    Biochem Biophys Res Commun; 2018 Jan; 495(1):1129-1135. PubMed ID: 29175333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1.
    Nada S; Okada M
    J Biochem; 2020 Dec; 168(6):621-632. PubMed ID: 32653916
    [TBL] [Abstract][Full Text] [Related]  

  • 7. O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.
    Xu C; Pan X; Wang D; Guan Y; Yang W; Chen X; Liu Y
    Mol Cell; 2023 Aug; 83(16):3027-3040.e11. PubMed ID: 37541260
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rheb may complex with RASSF1A to coordinate Hippo and TOR signaling.
    Nelson N; Clark GJ
    Oncotarget; 2016 Jun; 7(23):33821-31. PubMed ID: 27034171
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis.
    Xiong Z; Wang C; Wang Z; Dai H; Song Q; Zou Z; Xiao B; Zhao AZ; Bai X; Chen Z
    Biol Reprod; 2018 Dec; 99(6):1289-1302. PubMed ID: 29961810
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.
    Foster KG; Acosta-Jaquez HA; Romeo Y; Ekim B; Soliman GA; Carriere A; Roux PP; Ballif BA; Fingar DC
    J Biol Chem; 2010 Jan; 285(1):80-94. PubMed ID: 19864431
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Eukaryotic initiation factor 4E is a novel effector of mTORC1 signaling pathway in cross talk with Mnk1.
    Batool A; Majeed ST; Aashaq S; Majeed R; Bhat NN; Andrabi KI
    Mol Cell Biochem; 2020 Feb; 465(1-2):13-26. PubMed ID: 31782083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
    Wang Y; Tang S; Wu Y; Wan X; Zhou M; Li H; Zha X
    IUBMB Life; 2020 May; 72(5):965-977. PubMed ID: 31958214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ubiquitination of Rheb governs growth factor-induced mTORC1 activation.
    Deng L; Chen L; Zhao L; Xu Y; Peng X; Wang X; Ding L; Jin J; Teng H; Wang Y; Pan W; Yu F; Liao L; Li L; Ge X; Wang P
    Cell Res; 2019 Feb; 29(2):136-150. PubMed ID: 30514904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
    Yang H; Jiang X; Li B; Yang HJ; Miller M; Yang A; Dhar A; Pavletich NP
    Nature; 2017 Dec; 552(7685):368-373. PubMed ID: 29236692
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling.
    Xie J; De Poi SP; Humphrey SJ; Hein LK; Bruning JB; Pan W; Selth LA; Sargeant TJ; Proud CG
    Cell Mol Life Sci; 2021 Apr; 78(8):4035-4052. PubMed ID: 33834258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.
    Blackwood EA; Hofmann C; Santo Domingo M; Bilal AS; Sarakki A; Stauffer W; Arrieta A; Thuerauf DJ; Kolkhorst FW; Müller OJ; Jakobi T; Dieterich C; Katus HA; Doroudgar S; Glembotski CC
    Circ Res; 2019 Jan; 124(1):79-93. PubMed ID: 30582446
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
    Liu Z; Chen X; Wang Y; Peng H; Wang Y; Jing Y; Zhang H
    J Biol Chem; 2014 Oct; 289(43):29739-49. PubMed ID: 25164809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction.
    Ito M; Yurube T; Kakutani K; Maeno K; Takada T; Terashima Y; Kakiuchi Y; Takeoka Y; Miyazaki S; Kuroda R; Nishida K
    Osteoarthritis Cartilage; 2017 Dec; 25(12):2134-2146. PubMed ID: 28888905
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways.
    Xie CM; Tan M; Lin XT; Wu D; Jiang Y; Tan Y; Li H; Ma Y; Xiong X; Sun Y
    Cell Rep; 2019 Mar; 26(11):3037-3050.e4. PubMed ID: 30865892
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.