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7. Disordered breathing in a Pitt-Hopkins syndrome model involves Phox2b-expressing parafacial neurons and aberrant Nav1.8 expression. Cleary CM; James S; Maher BJ; Mulkey DK Nat Commun; 2021 Oct; 12(1):5962. PubMed ID: 34645823 [TBL] [Abstract][Full Text] [Related]
8. Impairment of different protein domains causes variable clinical presentation within Pitt-Hopkins syndrome and suggests intragenic molecular syndromology of TCF4. Bedeschi MF; Marangi G; Calvello MR; Ricciardi S; Leone FPC; Baccarin M; Guerneri S; Orteschi D; Murdolo M; Lattante S; Frangella S; Keena B; Harr MH; Zackai E; Zollino M Eur J Med Genet; 2017 Nov; 60(11):565-571. PubMed ID: 28807867 [TBL] [Abstract][Full Text] [Related]
9. Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons. Jung M; Häberle BM; Tschaikowsky T; Wittmann MT; Balta EA; Stadler VC; Zweier C; Dörfler A; Gloeckner CJ; Lie DC Mol Autism; 2018; 9():20. PubMed ID: 29588831 [TBL] [Abstract][Full Text] [Related]
10. Various haploinsufficiency mechanisms in Pitt-Hopkins syndrome. Sparber P; Filatova A; Anisimova I; Markova T; Voinova V; Chuhrova A; Tabakov V; Skoblov M Eur J Med Genet; 2020 Dec; 63(12):104088. PubMed ID: 33069932 [TBL] [Abstract][Full Text] [Related]
11. DNA methylation episignature and comparative epigenomic profiling for Pitt-Hopkins syndrome caused by TCF4 variants. van der Laan L; Lauffer P; Rooney K; Silva A; Haghshenas S; Relator R; Levy MA; Trajkova S; Huisman SA; Bijlsma EK; Kleefstra T; van Bon BW; Baysal Ö; Zweier C; Palomares-Bralo M; Fischer J; Szakszon K; Faivre L; Piton A; Mesman S; Hochstenbach R; Elting MW; van Hagen JM; Plomp AS; Mannens MMAM; Alders M; van Haelst MM; Ferrero GB; Brusco A; Henneman P; Sweetser DA; Sadikovic B; Vitobello A; Menke LA HGG Adv; 2024 Jul; 5(3):100289. PubMed ID: 38571311 [TBL] [Abstract][Full Text] [Related]
12. A case of Pitt-hopkins Syndrome with de novo mutation in TCF4: Clinical features and treatment for epilepsy. Liu Y; Guo Y; Liu P; Li F; Yang C; Song J; Hu J; Xin D; Chen Z Int J Dev Neurosci; 2018 Jun; 67():51-54. PubMed ID: 29604340 [TBL] [Abstract][Full Text] [Related]
13. Tcf4 dysfunction alters dorsal and ventral cortical neurogenesis in Pitt-Hopkins syndrome mouse model showing sexual dimorphism. Espinoza F; Carrazana R; Retamal-Fredes E; Ávila D; Papes F; Muotri AR; Ávila A Biochim Biophys Acta Mol Basis Dis; 2024 Jun; 1870(5):167178. PubMed ID: 38636614 [TBL] [Abstract][Full Text] [Related]
14. TCF4 Mutations Disrupt Synaptic Function Through Dysregulation of RIMBP2 in Patient-Derived Cortical Neurons. Davis BA; Chen HY; Ye Z; Ostlund I; Tippani M; Das D; Sripathy SR; Wang Y; Martin JM; Shim G; Panchwagh NM; Moses RL; Farinelli F; Bohlen JF; Li M; Luikart BW; Jaffe AE; Maher BJ Biol Psychiatry; 2024 Apr; 95(7):662-675. PubMed ID: 37573005 [TBL] [Abstract][Full Text] [Related]
16. Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder. Lee H; Thacker S; Sarn N; Dutta R; Eng C Transl Psychiatry; 2019 Jan; 9(1):13. PubMed ID: 30664625 [TBL] [Abstract][Full Text] [Related]
17. A typical variant in TCF4 exon 18 is not associated with Pitt-Hopkins syndrome but with a familial case of mild and nonspecific neurodevelopmental disorder. Aldeeri AA; Abu-El-Haija A Am J Med Genet A; 2023 Apr; 191(4):1070-1076. PubMed ID: 36574749 [TBL] [Abstract][Full Text] [Related]
18. Functional consequences of TCF4 missense substitutions associated with Pitt-Hopkins syndrome, mild intellectual disability, and schizophrenia. Sirp A; Roots K; Nurm K; Tuvikene J; Sepp M; Timmusk T J Biol Chem; 2021 Dec; 297(6):101381. PubMed ID: 34748727 [TBL] [Abstract][Full Text] [Related]
19. Pitt-Hopkins Syndrome: Clinical and Molecular Findings of a 5-Year-Old Patient. Tripon F; Bogliș A; Micheu C; Streață I; Bănescu C Genes (Basel); 2020 May; 11(6):. PubMed ID: 32481733 [TBL] [Abstract][Full Text] [Related]