These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Proteophenes - Amino Acid Functionalized Thiophene-based Fluorescent Ligands for Visualization of Protein Deposits in Tissue Sections with Alzheimer's Disease Pathology. Björk L; Bäck M; Lantz L; Ghetti B; Vidal R; Klingstedt T; Nilsson KPR Chemistry; 2022 Nov; 28(62):e202201557. PubMed ID: 35950816 [TBL] [Abstract][Full Text] [Related]
6. Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates. Klingstedt T; Shirani H; Mahler J; Wegenast-Braun BM; Nyström S; Goedert M; Jucker M; Nilsson KP Chemistry; 2015 Jun; 21(25):9072-82. PubMed ID: 26013403 [TBL] [Abstract][Full Text] [Related]
7. Thiophene-Based Ligands: Design, Synthesis and Their Utilization for Optical Assignment of Polymorphic-Disease-Associated Protein Aggregates. Björk L; Klingstedt T; Nilsson KPR Chembiochem; 2023 Jun; 24(11):e202300044. PubMed ID: 36891883 [TBL] [Abstract][Full Text] [Related]
8. Thiophene-Based Ligands for Specific Assignment of Distinct Aβ Pathologies in Alzheimer's Disease. Klingstedt T; Lantz L; Shirani H; Ge J; Hanrieder J; Vidal R; Ghetti B; Nilsson KPR ACS Chem Neurosci; 2024 Apr; 15(7):1581-1595. PubMed ID: 38523263 [TBL] [Abstract][Full Text] [Related]
9. Anionic Oligothiophenes Compete for Binding of X-34 but not PIB to Recombinant Aβ Amyloid Fibrils and Alzheimer's Disease Brain-Derived Aβ. Bäck M; Appelqvist H; LeVine H; Nilsson KP Chemistry; 2016 Dec; 22(51):18335-18338. PubMed ID: 27767229 [TBL] [Abstract][Full Text] [Related]
10. Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts. Simon RA; Shirani H; Aslund KO; Bäck M; Haroutunian V; Gandy S; Nilsson KP Chemistry; 2014 Sep; 20(39):12537-43. PubMed ID: 25111601 [TBL] [Abstract][Full Text] [Related]
11. The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates. Klingstedt T; Shirani H; Åslund KO; Cairns NJ; Sigurdson CJ; Goedert M; Nilsson KP Chemistry; 2013 Jul; 19(31):10179-92. PubMed ID: 23780508 [TBL] [Abstract][Full Text] [Related]
12. Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease. Rasmussen J; Mahler J; Beschorner N; Kaeser SA; Häsler LM; Baumann F; Nyström S; Portelius E; Blennow K; Lashley T; Fox NC; Sepulveda-Falla D; Glatzel M; Oblak AL; Ghetti B; Nilsson KPR; Hammarström P; Staufenbiel M; Walker LC; Jucker M Proc Natl Acad Sci U S A; 2017 Dec; 114(49):13018-13023. PubMed ID: 29158413 [TBL] [Abstract][Full Text] [Related]
13. Enhanced fluorescent assignment of protein aggregates by an oligothiophene-porphyrin-based amyloid ligand. Arja K; Sjölander D; Åslund A; Prokop S; Heppner FL; Konradsson P; Lindgren M; Hammarström P; Åslund KO; Nilsson KP Macromol Rapid Commun; 2013 May; 34(9):723-30. PubMed ID: 23468206 [TBL] [Abstract][Full Text] [Related]
14. Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates. Klingstedt T; Aslund A; Simon RA; Johansson LB; Mason JJ; Nyström S; Hammarström P; Nilsson KP Org Biomol Chem; 2011 Dec; 9(24):8356-70. PubMed ID: 22051883 [TBL] [Abstract][Full Text] [Related]
15. Spectral discrimination of cerebral amyloid lesions after peripheral application of luminescent conjugated oligothiophenes. Wegenast-Braun BM; Skodras A; Bayraktar G; Mahler J; Fritschi SK; Klingstedt T; Mason JJ; Hammarström P; Nilsson KP; Liebig C; Jucker M Am J Pathol; 2012 Dec; 181(6):1953-60. PubMed ID: 23041059 [TBL] [Abstract][Full Text] [Related]
16. Luminescent conjugated poly- and oligo-thiophenes: optical ligands for spectral assignment of a plethora of protein aggregates. Klingstedt T; Nilsson KP Biochem Soc Trans; 2012 Aug; 40(4):704-10. PubMed ID: 22817720 [TBL] [Abstract][Full Text] [Related]
17. Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands. Magnusson K; Simon R; Sjölander D; Sigurdson CJ; Hammarström P; Nilsson KP Prion; 2014; 8(4):319-29. PubMed ID: 25495506 [TBL] [Abstract][Full Text] [Related]
18. Distinct Heterocyclic Moieties Govern the Selectivity of Thiophene-Vinylene-Based Ligands Towards Aβ or Tau Pathology in Alzheime's Disease. Björk L; Shirani H; Todarwal Y; Linares M; Vidal R; Ghetti B; Norman P; Klingstedt T; Nilsson KPR European J Org Chem; 2023 Nov; 26(41):. PubMed ID: 38585413 [TBL] [Abstract][Full Text] [Related]