151 related articles for article (PubMed ID: 32022543)
1. Transition State Analogues Enhanced by Fragment-Based Structural Analysis: Bacterial Methylthioadenosine Nucleosidases.
Zhang D; Burdette BE; Wang Z; Karn K; Li HY; Schramm VL; Tyler PC; Evans GB; Wang S
Biochemistry; 2020 Feb; 59(7):831-835. PubMed ID: 32022543
[TBL] [Abstract][Full Text] [Related]
2. Transition State Analogue Inhibitors of 5'-Deoxyadenosine/5'-Methylthioadenosine Nucleosidase from Mycobacterium tuberculosis.
Namanja-Magliano HA; Evans GB; Harijan RK; Tyler PC; Schramm VL
Biochemistry; 2017 Sep; 56(38):5090-5098. PubMed ID: 28836767
[TBL] [Abstract][Full Text] [Related]
3. Residence Times for Femtomolar and Picomolar Inhibitors of MTANs.
Brown M; Tyler PC; Schramm VL
Biochemistry; 2023 Jun; 62(11):1776-1785. PubMed ID: 37204861
[TBL] [Abstract][Full Text] [Related]
4. Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase.
Harijan RK; Hoff O; Ducati RG; Firestone RS; Hirsch BM; Evans GB; Schramm VL; Tyler PC
J Med Chem; 2019 Apr; 62(7):3286-3296. PubMed ID: 30860833
[TBL] [Abstract][Full Text] [Related]
5. Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.
Guan R; Ho MC; Brenowitz M; Tyler PC; Evans GB; Almo SC; Schramm VL
Biochemistry; 2011 Nov; 50(47):10408-17. PubMed ID: 21985704
[TBL] [Abstract][Full Text] [Related]
6. Conformational freedom in tight binding enzymatic transition-state analogues.
Motley MW; Schramm VL; Schwartz SD
J Phys Chem B; 2013 Aug; 117(33):9591-7. PubMed ID: 23895500
[TBL] [Abstract][Full Text] [Related]
7. Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Rinaldo-Matthis A; Wing C; Ghanem M; Deng H; Wu P; Gupta A; Tyler PC; Evans GB; Furneaux RH; Almo SC; Wang CC; Schramm VL
Biochemistry; 2007 Jan; 46(3):659-68. PubMed ID: 17223688
[TBL] [Abstract][Full Text] [Related]
8. Catalytic site cooperativity in dimeric methylthioadenosine nucleosidase.
Wang S; Thomas K; Schramm VL
Biochemistry; 2014 Mar; 53(9):1527-35. PubMed ID: 24502544
[TBL] [Abstract][Full Text] [Related]
9. Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases.
Gutierrez JA; Luo M; Singh V; Li L; Brown RL; Norris GE; Evans GB; Furneaux RH; Tyler PC; Painter GF; Lenz DH; Schramm VL
ACS Chem Biol; 2007 Nov; 2(11):725-34. PubMed ID: 18030989
[TBL] [Abstract][Full Text] [Related]
10. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
Singh V; Shi W; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
Biochemistry; 2004 Jan; 43(1):9-18. PubMed ID: 14705926
[TBL] [Abstract][Full Text] [Related]
11. The Immucillins: Design, Synthesis and Application of Transition- State Analogues.
Evans GB; Schramm VL; Tyler PC
Curr Med Chem; 2015; 22(34):3897-909. PubMed ID: 26295462
[TBL] [Abstract][Full Text] [Related]
12. Transition state analogue of MTAP extends lifespan of APC
Firestone RS; Feng M; Basu I; Peregrina K; Augenlicht LH; Schramm VL
Sci Rep; 2021 Apr; 11(1):8844. PubMed ID: 33893330
[TBL] [Abstract][Full Text] [Related]
13. Tight binding enantiomers of pre-clinical drug candidates.
Evans GB; Cameron SA; Luxenburger A; Guan R; Suarez J; Thomas K; Schramm VL; Tyler PC
Bioorg Med Chem; 2015 Sep; 23(17):5326-33. PubMed ID: 26260335
[TBL] [Abstract][Full Text] [Related]
14. Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.
Clinch K; Evans GB; Fröhlich RF; Gulab SA; Gutierrez JA; Mason JM; Schramm VL; Tyler PC; Woolhouse AD
Bioorg Med Chem; 2012 Sep; 20(17):5181-7. PubMed ID: 22854195
[TBL] [Abstract][Full Text] [Related]
15. Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
Basu I; Locker J; Cassera MB; Belbin TJ; Merino EF; Dong X; Hemeon I; Evans GB; Guha C; Schramm VL
J Biol Chem; 2011 Feb; 286(6):4902-11. PubMed ID: 21135097
[TBL] [Abstract][Full Text] [Related]
16. Transition state analogues in quorum sensing and SAM recycling.
Schramm VL; Gutierrez JA; Cordovano G; Basu I; Guha C; Belbin TJ; Evans GB; Tyler PC; Furneaux RH
Nucleic Acids Symp Ser (Oxf); 2008; (52):75-6. PubMed ID: 18776260
[TBL] [Abstract][Full Text] [Related]
17. Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli.
Singh V; Evans GB; Lenz DH; Mason JM; Clinch K; Mee S; Painter GF; Tyler PC; Furneaux RH; Lee JE; Howell PL; Schramm VL
J Biol Chem; 2005 May; 280(18):18265-73. PubMed ID: 15749708
[TBL] [Abstract][Full Text] [Related]
18. Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Banco MT; Mishra V; Ostermann A; Schrader TE; Evans GB; Kovalevsky A; Ronning DR
Proc Natl Acad Sci U S A; 2016 Nov; 113(48):13756-13761. PubMed ID: 27856757
[TBL] [Abstract][Full Text] [Related]
19. Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis.
Brown M; Schramm VL
Biochemistry; 2023 Oct; 62(20):2928-2933. PubMed ID: 37788145
[TBL] [Abstract][Full Text] [Related]
20. Inverse heavy enzyme isotope effects in methylthioadenosine nucleosidases.
Brown M; Zoi I; Antoniou D; Namanja-Magliano HA; Schwartz SD; Schramm VL
Proc Natl Acad Sci U S A; 2021 Oct; 118(40):. PubMed ID: 34580228
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
