BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 32022556)

  • 1. The Soybean Lipoxygenase-Substrate Complex: Correlation between the Properties of Tunneling-Ready States and ENDOR-Detected Structures of Ground States.
    Offenbacher AR; Sharma A; Doan PE; Klinman JP; Hoffman BM
    Biochemistry; 2020 Feb; 59(7):901-910. PubMed ID: 32022556
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Horitani M; Offenbacher AR; Carr CA; Yu T; Hoeke V; Cutsail GE; Hammes-Schiffer S; Klinman JP; Hoffman BM
    J Am Chem Soc; 2017 Feb; 139(5):1984-1997. PubMed ID: 28121140
    [TBL] [Abstract][Full Text] [Related]  

  • 3.
    Sharma A; Whittington C; Jabed M; Hill SG; Kostenko A; Yu T; Li P; Doan PE; Hoffman BM; Offenbacher AR
    Biochemistry; 2023 May; 62(10):1531-1543. PubMed ID: 37115010
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Active Site Dynamical Effects in the Hydrogen Transfer Rate-limiting Step in the Catalysis of Linoleic Acid by Soybean Lipoxygenase-1 (SLO-1): Primary and Secondary Isotope Contributions.
    Phatak P; Venderley J; Debrota J; Li J; Iyengar SS
    J Phys Chem B; 2015 Jul; 119(30):9532-46. PubMed ID: 26079999
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Understanding Biological Hydrogen Transfer Through the Lens of Temperature Dependent Kinetic Isotope Effects.
    Klinman JP; Offenbacher AR
    Acc Chem Res; 2018 Sep; 51(9):1966-1974. PubMed ID: 30152685
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network.
    Hu S; Offenbacher AR; Thompson EM; Gee CL; Wilcoxen J; Carr CAM; Prigozhin DM; Yang V; Alber T; Britt RD; Fraser JS; Klinman JP
    J Am Chem Soc; 2019 Jan; 141(4):1555-1567. PubMed ID: 30645119
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.
    Knapp MJ; Rickert K; Klinman JP
    J Am Chem Soc; 2002 Apr; 124(15):3865-74. PubMed ID: 11942823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzyme dynamics and tunneling enhanced by compression in the hydrogen abstraction catalyzed by soybean lipoxygenase-1.
    Tejero I; Garcia-Viloca M; Gonzalez-Lafont A; Lluch JM; York DM
    J Phys Chem B; 2006 Dec; 110(48):24708-19. PubMed ID: 17134234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation.
    Hu S; Sharma SC; Scouras AD; Soudackov AV; Carr CA; Hammes-Schiffer S; Alber T; Klinman JP
    J Am Chem Soc; 2014 Jun; 136(23):8157-60. PubMed ID: 24884374
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impact of distal mutation on hydrogen transfer interface and substrate conformation in soybean lipoxygenase.
    Edwards SJ; Soudackov AV; Hammes-Schiffer S
    J Phys Chem B; 2010 May; 114(19):6653-60. PubMed ID: 20423074
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hydrogen-deuterium exchange reveals long-range dynamical allostery in soybean lipoxygenase.
    Offenbacher AR; Iavarone AT; Klinman JP
    J Biol Chem; 2018 Jan; 293(4):1138-1148. PubMed ID: 29191828
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigating inner-sphere reorganization via secondary kinetic isotope effects in the C-H cleavage reaction catalyzed by soybean lipoxygenase: tunneling in the substrate backbone as well as the transferred hydrogen.
    Meyer MP; Klinman JP
    J Am Chem Soc; 2011 Jan; 133(3):430-9. PubMed ID: 21192631
    [TBL] [Abstract][Full Text] [Related]  

  • 13. On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant.
    Coffa G; Imber AN; Maguire BC; Laxmikanthan G; Schneider C; Gaffney BJ; Brash AR
    J Biol Chem; 2005 Nov; 280(46):38756-66. PubMed ID: 16157595
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Density-functional investigation on the mechanism of H-atom abstraction by lipoxygenase.
    Lehnert N; Solomon EI
    J Biol Inorg Chem; 2003 Feb; 8(3):294-305. PubMed ID: 12589565
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Detecting and Characterizing the Kinetic Activation of Thermal Networks in Proteins: Thermal Transfer from a Distal, Solvent-Exposed Loop to the Active Site in Soybean Lipoxygenase.
    Zaragoza JPT; Nguy A; Minnetian N; Deng Z; Iavarone AT; Offenbacher AR; Klinman JP
    J Phys Chem B; 2019 Oct; 123(41):8662-8674. PubMed ID: 31580070
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinetic Detection of Orthogonal Protein and Chemical Coordinates in Enzyme Catalysis: Double Mutants of Soybean Lipoxygenase.
    Sharma SC; Klinman JP
    Biochemistry; 2015 Sep; 54(35):5447-56. PubMed ID: 26154975
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparative kinetic isotope effects on first- and second-order rate constants of soybean lipoxygenase variants uncover a substrate-binding network.
    Hu S; Offenbacher AR; Lu ED; Klinman JP
    J Biol Chem; 2019 Nov; 294(48):18069-18076. PubMed ID: 31624150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hydrogen tunneling and protein motion in enzyme reactions.
    Hammes-Schiffer S
    Acc Chem Res; 2006 Feb; 39(2):93-100. PubMed ID: 16489728
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nature of hydrogen transfer in soybean lipoxygenase 1: separation of primary and secondary isotope effects.
    Rickert KW; Klinman JP
    Biochemistry; 1999 Sep; 38(38):12218-28. PubMed ID: 10493789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetic Characterization of the C-H Activation Step for the Lipoxygenase from the Pathogenic Fungus
    Kostenko A; Ray K; Iavarone AT; Offenbacher AR
    Biochemistry; 2019 Jul; 58(29):3193-3203. PubMed ID: 31264852
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.